دراسة التأثيرات المرضية والنسجية لديدان الصفر الخراطيمي Ascaris lumbericoides في اناث الجرذان البيض

Abstract

The current study was conducted in the period from September 2011 till September 2012 to study the histological and pathological effects of Ascaris lumbericoides in experimental infected rat. the laboratory animals divided to four groups ( three of them groups infected by the parasites of the study and one control) treated by different concentrations (500,1000,2000) eggs/1 ml , the experiment continuous for two months treated by once in one day and by different time, the result appear histological changes for some organs of infected animals by 2000 eggs /1 ml these were more effective compared with other groups ,the lung more effective organs was noticed destruction and increasing bronchi thickness and ulceration of lumen tracheal and destruction of B-Nemocytes (Type-2), and noticed histological changes in small intestines is showed hypertrophy and destruction microvillus and columnar cells that lined and obstruction mucosa and sub mucosa layer , while liver is show expanded in central vein of lobules congestion and bloody hemorrhage and polymorphic nucleus infiltration, furthermore heart organ was noticed absent of striation of myocardium and not appear nuclei ,finally pharynx is show not any changes it.