Antimicrobial Activity for Crude Watery Extract of Seeds of Citrus aurantifolia (Lime fruit) against Gram Positive and Negative Bacteria In Vitro

Abstract

The effect of crude watery extract for seeds of Citrus aurantifolia (Lime fruit) was tested against different clinical isolates including Staphylococus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Klebsiella pneumoniae and Proteus vulgaris. The inhibitory effect for watery extract was carried out by agar well diffusion method and represented as inhibition zones around wells and measured with millimeter unite; the large zones are linked with concentration 10, 20, 40 % of seed extract, the antimicrobial activity of crude seeds extract may be attributed to bioactive compound present in it. The results obtained shown that the crude seeds watery extract of C. aurantifolia fruit can be considered as good source of antimicrobial compounds and can be used as alternative therapy for many infectious diseases and can be incorporated into different drug formulations.