Study of honey bee effect on melatonin concentration and many immunological and biochemical parameters in women suffering Chronic kidney disease in Kirkuk city

Abstract

The present study designed to demonstrate positive effect for honey bee on melatonin conc. and some immunological and biochemical parameters in women suffering Chronic kidney disease (CKD), the study include (55) blood samples get from women with CKD , (21) women from them volunteered to eat natural honey for thirty days, compared with (20) samples for normal women as control with age (20-49)year ,the samples were collected from Kirkuk hospital and clinicals from febreuary/2015 to june/2015.We reach to following conclusions: high significant increase in creatinin ,urea ,uric acid conc. And Melatonin ,MDA, Leptin ,IL-1α , IL-6 and TNF-α in women suffering from CKD compared with control group. whereas we found high significant decreasing in Albumin, GSH, Ceruloplasmin conc. In women with CKD compared with control . there were high significant decrease in biological ,immunological parameters with high significant increasing in Melatonin, Albumin, GSH, Ceruloplasmin in women with CKD and eat natural honey in compare with women with CKD without treatment with honey .