Biochemical study for Alanine amino peptidase isoenzymes of abortion

Abstract

AbstractThe study was included (66) undiagnosed aborted women at different stage of pregnancy compared with (40)healthy subjects as control groups .A high significant increase (P:Q.05) in The activity of alanine aminopeptidase in urine of single &recurrentabortion first & secondtrimesters were shown (5.3+0.33) (10.E5*0.05)U/L qand (14.5+0.39) (22.71A.72)Ullrespectively compared to healthy subject (5i!A.24') (5.4+0.48) and (4.3+0.295)U/L for normal pregnant (1"trimesters) , (2 nd trimesters) and non pregnant women . AAP was purified from urine of aborted women bygel-filtration using sephadex (G-50) and two isoenzymes of AAP I,II were separated fiom urine samples byusing DEAE-cellulos .