The Role of Omega-3 EPA/DHA Oral Soft gel in The Treatment of Stable Bronchiectasis

Abstract

The omega 3 has a known anti-inflammatory effect which can be beneficial in many human diseases in the respiratory & other systems. In respiratory system its role is not mature yet as in asthma, COPD & bronchiectasis & most are still under study.The safety issues also need to be addressed in the treatment with a relatively need medication.To evaluate the use of omega-3 EPA/DHA oral softgel in the treatment of stable (not in exacerbation) bronchiectasis regarding safety/efficacy effect.44 Patients with stable bronchiectasis are randomly assigned to the active group (participants receive omega-3 EPA/DHA oral softgel (EPA 180mg &DHA 120mg ) once daily for 6 months in addition to their usual treatment) or the control group (participants receive the usual treatment only for 4 months) from January 2013 to march 2016.Interventional randomized parallel assignment study concern in the safety /efficacy of a suggested treatment.Omega 3 can used in patients with stable bronchiectasis with the expected benefits:1- reduce exacerbation rate2- improve FEV13- may improve CAT score The treatment does not cause serious side effects regarding the safety aspect apart from the fishy odor sensed by the patients .