Ethanol effect in induce histological lesions in Albino rat livers and using camel milk and olive oil to treat it

Abstract

This study was designed to identify the influence of alcohol in the creation of histological lesions in the liver of Albino rats type Rattus norvegicus and treating these effects using camel milk and olive oil, in this study, 15 rats were randomly distributed into five groups each group containing three animals, the first group control group It was fed on a routine diet and administrated with distilled water, either groups 2, 3, 4,5 administrated with alcohol for 3 months at a dose began 10% V / V / day and gradually increase to up to 15% v / v / day, and then the animals Group 3 treated by ad libitum camel milk open dose for one month, Group 4 animals administrated with olive oil rate of 0.2 ml / kg body weight, Group 5 animals administrated by camel milk and olive oil together, the results of the current study, the second group showed the occurrence of a number of the histopathological lesions in the liver tissue consisted infiltration of lymphocytes with the occurrence of fibrosis within the liver tissue and thickening walls of the blood vessels that have suffered from the expansion of abnormal diameters ,in the third group most liver tissues return to semi-natural state had been observed after treating via camel milk for a one month with the presence of some simple histological changes in the liver tissue. The fourth group was also back to normal case in most of liver tissues. The fifth group was noted that the tissue response to the dual treatment was the best compared to the third and fourth groups and the tissue had completely healed and appeared as normal.