Clinical and Histopathological Features of Ovarian Cancer in Rizgary Hospital/Erbil City from 2014 to 2017

Abstract

Background: Ovarian cancer is a heterogeneous disease with variations in clinical behavior and outcome. It is a group of many subtypes withdistinct biological features that lead to differences in response to treatments, recurrence rates, and survival. Objective: The aim of the studyis to describe the epidemiology of the diagnosed cases of ovarian cancer from 2014 to 2017 in Erbil, Iraq. Materials and Methods: This is aretrospective study, 100 ovarian cancer cases were reviewed from Rizgary Oncology Center in Erbil. Then, we compared histological typeswith age groups of the study as premenopausal and postmenopausal, stage of the disease, grade, and with side of tumor. Furthermore, this studyincludes the most important risk factors that may affect the incidence of ovarian cancer which includes menarche age, age of menopause, andwith obesity. Results: The result showed that ovarian cancer occurs in old age groups with a percentage of 64%. The most common type isepithelial ovarian cancer with subtype papillary serous adenocarcinoma in 56%, with all types, the most affected site is the right one in a percentof 57%. Grade 3 is the dominant one at presentation in a percent of 49%. About staging at the time of diagnosis, Stage 4 presented in a percentof 58%, and 16% of patients were obese. Conclusion: Most common type of cancer is epithelial type of papillary serous cystadenocarcinomahistology that occur in old patients and presented in advanced stage at the time of diagnosis with poor differentiation, and the most effectivetreatment is total abdominal hysterectomy + bilateral salpingo‑oophorectomy followed by adjuvant platinum‑based chemotherapy.