Effect of Hydroxy urea on cancer cells

Abstract

This research aims to explore the in vitro antitumor activity of the compound hydroxy urea (synthesized in the laboratory).Two cell lines were used, the first from epidermal larynx and the second from mammary glands of mice.The cytotoxic effect of this compound started with Initial concentration (62.5 μg/ml) for the cell line of larynx but started at higher concentration (125 μg/ml) for the cell lines of mammary gland, and the activity Increases with concentration and time which means it is concentration and time dependant .It was cocluded from this study that the toxicity of hydroxy urea increased with increasing the concentration and time of exposure