Low Concentrations of Maternal Thyroxin During Early Gestation :A Risk Factor of Breech Presentation

Abstract

ABSTRACT:BACKGROUND:Approximately 3-5% of all pregnancies at term are with the fetus in the breech presentation in whichwhatever thier mode of delivery, is a signal for potential fetal handicap Little is known about theetiology; However there are several etiological factors might be related to fetal movement duringpregnancy. Maternal hypothyroxinaema early in gestation may have effect on fetal movement duringpregnancy through its effect on fetal brain maturation.OBJECTIVE:To evaluate the relation between breech presentation at term and low maternal free thyroxin levelsduring early gestation in women not suffering from overt thyroid dysfunction.DesignA prospective observational study of pregnant women.METHODS:Analysis refers to 70 women who met the inclusion and exclusion criteria. Main outcome assessment,Fetal presentation (cephalic–breech) at term gestation in relation to maternal thyroid function at 12weeks of gestationRESULTS:Breech presentation at term delivery was independently related to maternal free thyroxin ( fT4 ) levels<10th cectile at 12 weeks of gestation (OR 4.63, 95% CI 0.8- 22)CONCLUSION:Women with hypothyroxinaemia ( FT level <10th centile) during their early gestation (without overtthyroid dysfunction) are at risk for persistent breech presentation