Predictive about the Genetic Effect of Salvia officinalis Extracts on the Fungus Aspergillus amstelodami

Abstract

The study aimed to detected of the ability extract hot water and alcohol extract of plant Salvia officinalis to cause genetic effects on Eukaryotic cells, by indicating the ability of these extract to induce genetic mutation in the conidia of fungus Aspergillus amstelodami using three mutation methods, pretreatment method, growth mediated method and plate incorporation method, the study didn’t record any mutagenic effect at four sub lethal concentration 15, 20, 25, 30 mg/ml of hot water extract and 0.3, 0.5, 0.7, 0.9 mg/ml of alcoholic extract and through the study of alcoholic extract at concentration of 0.9 mg/ml in calculating mitotic index of the division stages of onion root after 24-84 hours period of exposure, the study didn’t record any effect on the chromosomal group during division stages and the chromosomal shape and this assure the safety of using Salvia officinalis in the different life styles.