Study of insulin and complete lipid profile in non insulin dependent diabetes mellitus

Abstract

The aim of this study was determinate of insulin and complete lipid profile in patients of type 2 diabetes and explain the effects of insulin on complete lipid profile. The investigation was carried out in a group of 45 patients, suffering from type 2 diabetes treated by oral hypoglycemising medicines. Blood serum was used to determine enzymatically the concentration of lipid: total cholesterol, High Density Lipoprotein (HDL), Low Density Lipoprotein (LDL), triglycerides, Very Low Density Lipoprotein (VLDL) and insulin. The results revealed significantly increased in cholesterol, LDL, Tg and VLDL (191.66, 112.35, 196.35, 39.89) mg/ dl when compared with control (141.76, 66.22, 121.31, 24.26 )mg/ dl. HDL concentration and insulin were significantly decreased (33.33 mg/ dl, 4.50 µl U/ ml) when compared with control (40.60 mg/ dl, 5.01 µl U/ ml). The results revealed correlation between concentration of insulin and complete lipid profile.