Study the effect of Staphylococcus aureus bacteriocines at normal and Cancer cells in vitro

Abstract

The toxic effect of the bacteriocines which extracted from Staphylococcus aureus, isolated from medical samples, on the cancer cells line (Hela) of human cervix and on human embryo cells line (L20B) were estimation the ratio of living cells after treated for 24,48 and 72 hours. The results showed that there are toxic effect on (Hela) cells growth which treated for 72 hour with (B6) and (B11) bacteriocin. On other hand the results showed that there are atoxic effect on the growth of (L20B) cells which treated for 24 hour by using the low concentrations for the tow bacteriocin types when treated for 72 hour with low concentration of (B6) bacteriocin and with high concentration of (B11) bacteriocin. The study were be confirmed the ability of (B6 and B11) bacteriocin to reduce the living cells ratio for (Hela), these effects were confined on the (L20B) cells at the Low ratio for (Hela), these effects were confined on the (L20B) cells at the Low concentration concentrations from (B6) and high concentrations from (B11) bacteriocin at 72 treated hour.