Preparation of some Benzimidazole derivatives and study of their spectrometric properties and biological activity

Abstract

This research discussed the preparation of some derivatives of Benzimidazole which included Schiff base compounds (a-e). They were prepared by direct condensation between Benzimidazole and aliphatic or aromatic aldehydes. The prepared compounds were identified by Infrared spectra (I.R.), micro analysis of elements (C.H.N.), Nuclear magnetic resonance spectrum (N.M.R.) and (MS) spectrum.Antibacterial activity of the prepared compounds was measured on three genus of pathogenic bacteria. The comparative study of biological activity was done using diffusion , and antibacterial activity was noticed in some of these compounds.