Studies of histopathological changes in lab animals Infected with Nocardia asteroids

Abstract

To study the ability of N.asteroids to cause pulmonary, cutaneas and dissemintal infection, mice were infected with bacterial suspension by inhalation and injection of the bacteria in the food pad and rabbits were injected intra-veneously. Histopathological investigation indicated the ability of N.asteroids to induce pulmonary infection by histopathological destruction which after (14,21,30,45,75) day of bacterial inhalation which showed the ability of this bacteria to cause lesions on lung tissue both macroscopically and microscopically , Histopathological study showed the ability of the bacteria to intrate cutaneous infection to colonize skin and causing histopathological of the right food pad injected with the bacterial suspension , as well as the study also showed its ability to cause systemic infection which was indicated from its ability to colonize and causing lesions and histopathological changes in the