Determination of GLUT3 and GLUT8 Protein in the Testis of Diabetic Rats Treated with Aqueous Eextract of Cymbopogon* Citrates

Abstract

The present study was designed to obtain the localization of (glucose transporter 3) GLUT3 and GLUT8 protein in the testis of diabetic rats which were treated by aqueous extract of Cymbopogon citratus (100 mg/kg) once daily. Diabetes induced to the labratory animals (Sprague dawly rats) by alloxan injection (90 mg / kg .bw. by a single intraperitonial injection). The experiment lasted for five months during which the animals were divided into diabetic and non-diabetic normal groups. Significant increase was obtained in the localization of (glucose transporter 3) GLUT3 protein in diabetic testis in all age groups, with significant decrease in both (glucose transporter 8) GLUT8 protein localization in testes in all age groups in comparisons with normal groups. In brief the herb used in this study resulted in the increase in GLUT8 protein ( glucose transporter 8) with decrease in GLUT3 protein ( glucose transporter 3), therefore one can conclude that the herb might be used for the minimized the disorder of male reproductive during diabetes.