Immunological Study of infection with Toxoplasma gondii in Al-Diwanyia City

Abstract

This research aimed to determine some humeral immune aspects in infected people with toxoplasmosis. Total of 56 sample as 38 sample of infected women and 18 healthy controls their ages ranged between 20-39 years old. Results showed a significant elevation (P<0.05) in IgG levels in patients group 112.4 ± 91.87 mg/dl in comparison to control group 850.99 ± 75.78 mg/dl. Also results showed a significant reduction (P<0.05) in IgM levels in the patients group 103.9± 8.31 mg/dl comparison to control group 412.95±112.4 mg/dl. IgA levels were non significantly elevated 197.29 ±17.3 mg/dl comparison to control group 149.2 ±30.22 mg/dl . C3 levels were also non significantly elevated 135.38±11.29 mg/dl in comparison to control group 107.57±16.33mg/dl. Also C4 levels were also non significantly elevated 32.53 ±2.61mg/dl in comparison to control group which was 23. 29± 2.42 mg/dl. The infection with this parasite induce the antibody formation as an immune response which affect the parasite during the short period in which the parasite become out side the cells, then die by the specific antibodies when bide to the complement that archive the level of the immune response in patients determine the parasite pathogenesis.