The influence of menopause on unstimulated salivary flow and subjective oral dryness inrelation to other oral symptoms and salivary gland hypofunction

Abstract

Background: The aim of the present study was to evaluate unstimulated salivary flow rate and oral symptoms inmenopausal women.Materials and Methods: A total of 200 individuals including 100 women in their menopause (case group) and 100men in the same age range (control group) participated in this analytic descriptive investigation. None of thepatients were being treated for any systemic disease or taking any medication. Unstimulated salivary flow rate wasmeasured using the spitting method and the prevalence of oral symptoms was evaluated by filling out aquestionnaire. The results were analyzed with ANOVA, chi-square and Student’s t-test (P<0.05).Results: The average of unstimulated salivary flow rate was 0.127 ml/min (SD=0.057) in women and 0.214 ml/min(SD=0.105) in men. The prevalence of dry mouth was 50% versus32%, difficulty in eating dry foods 31% versus 8%,burning sensation in oral mucosa 3% versus 0%, taste reduction, 4% versus 2% and bitter or metallic taste 16% versus8% in female and male subjects, respectively.Conclusion: A significant difference in salivary flow rate and prevalence of oral symptoms was found between thetwo groups (P<0.05). Reduced salivary flow rate and a high prevalence of oral symptoms in menopausal womenmay be related to the hormonal alterations that occur during this period