تأثير مستخلص نبات الدفلة Nerium oleander في نمو وتطور الاكياس العدرية للمشوكة الحبيبية Echinococcus granulosus في الفئران البيض Balb/c

Abstract

The present study was conducted during the period from September 2010 till April 2011 to evaluate the effect of active materials (alkaloids and phenols) of Nerium oleander activity on viability of the protoscolices In vivo of Echinococcus granulosus in white mice (Mus musculus) type Balb /c . The protoscolices were collected from sheep livers in Al-Hilla abattoir in Babylon province . The percentage of the viability of protoscolices was measured by using the eosin aqueous stain (0.1) . The results of the study revealed that there are statistically significant for the alkaloides concentration 270 mg/ml/mice and phenols concentration 280 mg/ml/mice decreased the weight and diameters of cysts (4.1، 3.8) millimeter respectively in comparison with positive control group (6.0) milimeter . and the alkaloids and phenols concentrations (270 ، 280) mg/ml respectively gives relative drug efficiency equals (55.17 % , 48.27 % respectively) .