ESTIMATION THE SERUM CONCENTRATION OF INTERLUKINE 2 RECEPTORS IN PATIENTS WITH RHEUMATOID ARTHRITIS

Abstract

Serum soluble interleukin 2 receptors (sIL-2R) concentration reflect lymphocyte activation in vivo. The present study was conducted to determine if sIL-2R concentration correlate to disease activity parameters in patients with rheumatoid arthritis (RA) compared with healthy populations. One hundred blood samples were collected, from RA patients and thirty from apparently healthy groups. The mean age of RA patients was 46.75±12.82 and, the majority of patients were females (84%). The level of sIL-2R was estimated serologically by using enzyme linked immunosorbant assay. The result indicated that the sIL-2R was elevated significantly (mean 2101.67± 1899.21) in RA compared with healthy control group (mean16.76±5.75).