Table of content

Iraqi Journal of Embryos and Infertility Researches

المجلة العراقية لبحوث الأجنة والعقم

ISSN: eISSN: 26166984 / pISSN: 22180265
Publisher: Al-Nahrain University
Faculty: Embryo research and treatment of infertility
Language: English

This journal is Open Access

About

Iraqi journal of embryos and infertility research is apeer-reviewed journal published annually by the High Institute of Infertility Diagnosis and Assisted Reproductive Technologies/Al-Nahrain University,
it publishes manuscripts in the fields of reproductive medicine.

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Contact info

E-mail: haydermossa@gmail.com

E-mail: ijeir.info@ierit.nahrainuniv.edu.iq

Website : http://www.ijeir.nahrainuniv.edu.iq

Table of content: 2011 volume:1 issue:1

Article
Ultrastructural and morphometric study of the glomerular filtration slit during neonatal period
دراسة التركيب المستدق وقياس الشكل لفلعة الترشيح الكبيبي خلال الدور الوليدي

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Abstract

Background The functional and morphological development of the glomerius is an essential part of nephrogenesis that takes place during Intra uterine life and early post-naiat days. Objectives To study the morphometric parameters of the maturation of the glomerular filtration slit of the kidney during neonatal period and its implication on the function of the kidney. Memod Rat litters are used as a mammalian model of the development during the first 8 days of post -natal life. Image analysis using Bell software system was used for morphmetric measurement of filtration silt as examined by electron microscope- Results The width of the filtration slit of new born kidney was 11.24±1.6 nm which increased by increment to be 14.83+1,6 nm on 4th .post- natai day. Eventually reached 25.34±4.3 nm on day 8 post natally. Conclusions In New Born litters, the glomerular filtration slit is narrower than that of mature kidney. Glomerular development continues to take place during first post natal week to reach the adult mature parameters at the end of neonatal period. This explains the low GFR found in new born mammals.

Keywords

Glomerulus --- Development --- GFR


Article
Correlation between intra uterine insemination outcome and Kruger strict criteria using two staining methods to detect the sperm morphology of infertile men
العلاقة بين نتائج التلقيح الاصطناعي والمعايير المحددة لطريقة كروكر باستخدام نوعين من الصبغات لتحديد شكلياء النطف في الرجال العقيمين

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Abstract

Background Since 1999 , the World Health Organization (WHO) recommended the assessment of sperm morphology by Kruger strict criteria(KSC), The manual of WHO contains the cut off values of sperm morphology measured by KSC for normal subject and patients treated by in vitro fertilization (IVF) and intra- I cytoplasmic sperm injection(ICSI) without any information regarding intrauterine insemination( IUI). Objectives The objective of this study is to achieve two major goals that are :1-Assessment of sperm morphology by applying KSC , using two different biological stains, named commercially Testsimplets {TS)pre-stained slides and Sperm-O-Scan (SOS)stain 2-To have a cut off value for morphologically normal sperm that resulting into a successful IUI outcome. Materials and Methods; Fifty five unselected couples attending the Institute of Embryo Researches and Infertility Treatment were included in this prospective study from December 2007 til) August 2008 ,The mean age of male partner was 31,7±1-87years with an average duration of 6<25±1.65years of infertility. The women were prepared for IUI. All the males were subjected to semen analysis with in vitro sperm I activation using layering swim-up technique. Assessments of the morphologically normal sperm(MNS) of the samples were performed by using both, High power field and KSC by using TS and SOS stains before and after the activation. Correlation of the positive IUI results and MNS by KSC waw recorded denoting the cut off value for successful results. Results The mean of morphologically normal sperm applying KSC with the use of SOS Stain before in vitro sperm activation was 16.10% and after activation was 37.85% and by using TS stain before in vitro sperm activation was 15.14% and after activation was 37.09% No significant (P>0.05) differences was detected between the results of MNS of the two stains. The result of IUI was 11 positive pregnancies out of the 55 cases. The mean of MNS using KSC for these positive cases was 11.58% and 12.84% for SOS and TS stains, respectively. Conclusions The cut off value of MNS by applying KSC and using two different I biological stains for a successful IUI program was 11.58% by SOS stain and 12.84% by TS pre-stained slides. Although the study found no statistical differences between the two stains, TS found to be easier, I simpler and less time consuming technically than SOS stain.


Article
Effect of lead exposure on the development of polycystic ovary syndrome
تاثير الرصاص في نشوء مرض تكيس المبايض

Authors: نوال خيري حسين
Pages: 23-30
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Abstract

Background The effects of Lead and other essential metal like zinc and copper on the reproductive system have been previously reviewed. Objective Our goal in this study was to estimate the levels of Lead, Zinc and Copper in patients with polycystic ovary syndrome and to confirm the effect of such metals on the female reproductive system at environmental exposure Materials and Method Fifty two women in their reproductive age (20-40) years old, which had been diagnosed as PCQS. Venous blood sample were taken from each patient and control, blood lead, zinc and copper were determined by atomic absorption spectrophotometer Hormone assay were determined by ELISA (Enzyme Linked Immune Sorbet Assay) technique. Results This study showed a significant increase of blood lead and serum zinc, copper (p<0.01),jn addition to testosterone, lutenizing hormone, LH/FSH ratio and body mass index (BMI) (p<0.05) in patients with polycystic ovary syndrome when compared with control. Conclusions On the basis of the observations of the present study, it can conclude that the increased levels of Lead as a result of the exposure to this metal may be a risk factor for the development of polycystic ovary syndrome in women and has adverse effects on female endocrine and reproductive function,

Keywords

Infertility --- PCOS --- Uad --- Zinc --- Copper


Article
Relevance of seminal plasma fructose concentrations to male infertility
استكشاف العلاقة بين سكر الفركتوز والكلوكوز في السائل المنوي ومرض عقم الرجال

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Abstract

Background Seminal fructose is derived from the seminal vesicle and is therefore a suitable marker for its function. Fructose is the energy source for sperm and may have an importance in pathological conditions of semen, e.g. in asthenozoosperrnia. Objective To find out if there is a correlation between seminal plasma fructose Level and sperm concentration and motility in infertile Iraqi men. In addition, the study assessed the reliability of using seminaI fructose concentr ation as indicator of seminal vesicles function. Parents and Methods Forty six infertile men, free from infectious disease or endocrine disorders, were selected for the study. Control group, selected from couples with proven male fertility, were 10 fertile men. Semen samples, collected from theses fertile and infertile men, were analyzed for general seminal fluid examination and fructose concentration determination. Results Seminal fructose has been noticed to have significant negative correlations with sperm count, with percentage of motile sperm and with absolute number of motile sperms. These negative correlations may be due to increased rate of fructolysis with higher sperm count and motility or due to an endocrine cause related to relatively high FSH in infertile men. To use seminal plasma fructose as a marker for seminal vesicles function, a correction for the opposing factors that affect fructose level such as sperm count and motility is carried out. Corrected seminal fructose is positively correlated with the total number of motiie sperm. Furthermore, a positive correlation between true corrected fructose and the percentage as well as the total number of motile sperm has been found. ** Conclusion Seminal fructose level has an inverse correlation with sperm count and percentage and number of motile sperm in the study group. Seminal fructose is a good marker of seminal vesicle function after using the correction formula


Article
Effect of aqueous and ethanolic extracts of Tribulus terrestris, Phoenix dactylifera and Nasturtium officinale on the reproductive organs in male mice
تاثيرالمستخلص المائي والكحولي لمزيج من نباتات الكطب وطلع النخيل والرشاد على الاعضاء التناسلية في ذكور الفئران

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Abstract

Background A mixture of three plants was used in this study: Tribulus terrestris (TT), Phoenix dactylifera (Pd) and Nasturtium officinale (No) which were believed to have fertility enhancing effects. Objectives To study the effects of the aqueous and ethanoholic extracts of the mixture of the three plants on body weight and some reproductive organs parameters in male mice Material and Methods Extracts of the mixture of the three plants were injected intraperitoneally at doses of 75,150 and 300mg/kg/day to male mice for a period of one and two weeks. Body weight and reproductive organs weight were recorded. The height and diameter of the epithelial lining cells of the epididymis and seminiferous tubules were evaluated by the end of the two periods through histological preparations. Result: Both extracts showed a significant increase in body weight and reproductive organs weight as well as the diameter and height of the epithelial lining cells of the seminiferous tubules and epididymis. Conclusion: A dose dependent pattern of effects was noticed in both extracts with more obvious effects resulted by the ethanoholic extract.

Table of content: volume:1 issue:1