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The Antagonistic role of Cinnamon on a destructive effect 0f Alloxan on the rat testis . A Histological Study

Authors: Mahera N . Al - Shaikh --- Ma'an H . Al - Khalasi --- Nameer T . George
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2006 Volume: 5 Issue: 1 Pages: 110-115
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT: BACKGROUND: Diabetes mellitus is a chronic metabolic disorder characterized by a high blood glucose concentration (hyperglycemia ) which is due to insulin deficiency and / or insulin resistance . As a consequence of the metabolic derangements various complications develop , so the aim of this investigation is to study(histological ) the role of cinnamon – oil on the testis tissue of alloxan – induced diabetes rat . METHODS AND METHODS : Forty -six male rats were used and divided into 3 groups : group I , 6 = animal control . group II , 20 = treated with alloxan and the 3 rd group , 20 = treated with alloxan + cinnamon . RESULTS : Testis of group I revealed normal distribution of seminiferous tubules and spermatozoa filled the lumen of these tubules . Group II showed reduction in number of seminiferous tubules , and absence of spermatozoa in their lumen , besides the significant decrease in testis weight . Group III elicited retrained these changes to approximately its normal view . CONCLUSION : This herbs ( cinnamon ) decrease or protect the destructive effect of alloxan on testis tissue

Keywords

: Alloxan --- Cinnamon --- Diabetes --- Testis.


Article
BIOLOGICAL ACTIVITIES OF LONG TERM TREATMENTS WITH HALOXYLON SALICORNICUM AND GLIBENCLAMIDE IN NORMAL AND ALLOXAN HYPERGLYCEMIC DIABETIC RABBITS
دراسة الفعالية البايلوجية ذات المدى الطويل للارانب المعاملة مع نبات الشنان ودواء الطبيعية والمستحدث بها داء السكر بواسطة الالوكسان

Author: AL-Saeed,M.H. منى حميد محمود السعيد
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2006 Volume: 5 Issue: 1 Pages: 50-57
Publisher: Basrah University جامعة البصرة

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Abstract

Hypoglycemic activity of Haloxylon salicornicum and Glibenclamide were studied innormal and diabetic rabbits. The drugs were adminstered once daily at dose of lg / Kg atH.salicorm'cum and 10 mg / Kg at Glibenclamide by gavage for one month. Serum glucoselevel, creatinine level, total bilirubine and total protein were reduced significantly in 15-30days. The serum Transaminase (AST and ALT activities) had effect on the treated groups.

Keywords

Alloxan --- Rabbits --- Creatinine

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