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Article
Renal Involvement in 25 Patients with Systemic Sclerosis

Authors: Nizar Abdulateef Jassim --- Ziad Shafeek Al-Rawi --- Ali Abdumajeed Diab --- Ali Nazar Mohammed
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2009 Volume: 8 Issue: 1 Pages: 1-6
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND:Renal involvement is considered a poor prognostic factor and not frequently a cause of death in patients with scleroderma. Renal involvement can be divided into scleroderma renal crisis and non-renal crisis abnormalities.OBJECTIVE:To evaluate the frequency of renal involvement in 25 Iraqi patients with systemic sclerosis (SSc).METHODS:Twenty five patients with SSc (21 female and 4 male) were included in a case-controlled study. All patients fulfilled the American College of Rheumatology criteria for SSc. All patients were of diffuse type. Other types of SSc were excluded. All patients underwent measurement of blood pressure and investigations had been done for them which included: hemoglobin (Hb), white blood cell (WBC) count, platelet count, erythrocyte sedimentation rate (ESR), blood urea (BU), serum creatinine (SCr), general urine examination (GUE), and rheumatoid factor (RF). Same investigations were done for 25 healthy person (considered as control group).RESULT:All patients (100%) had Raynaud’s phenomenon, 23 patients (29%) had dysphagia, 21 patients (84%) had arthralgia, 10 patients (40%) had telangiectasia and 2 patients (8%) had subcutaneous calcification. Three patients (12%) had moderate hypertension. Fourteen patients (56%) had anemia, 2 patients (8%) had leukocytosis, 6 patients (24%) had elevated ESR, 1 patient (4%) had elevated BU, 1 patient (4%) had albuminuria and 4 patients (16%) had positive RF. Platelet count and SCr were normal in all patients. Only 1 patient (4%) had renal involvement in form of combination of azotemia, albuminuria and hypertension.CONCLUSION:Renal involvement in systemic sclerosis among Iraqi patients is rare.

Keywords

renal --- iraqi --- systemic sclerosis.


Article
Pulmonary changes findings in patients with systemic sclerosis by high resolution computed tomography
رئوي التغييرات في نتائج مرضى التصلب الجهازي بواسطة التصوير المقطعي ارتفاع القرار

Author: Sameer K. Muhammad سمير خيرالله محمود
Journal: The Medical Journal of Tikrit مجلة تكريت الطبية ISSN: 16831813 Year: 2009 Volume: 1 Issue: 151 Pages: 117-123
Publisher: Tikrit University جامعة تكريت

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Abstract

This study was done to assess the ability of high resolution computed tomography (HRCT) in detecting the early signs of pulmonary involvement in patients with systemic sclerosis (SSc). The chest in ten patients with established diagnosis of SSc according to American College of Rheumatology criteria for classification of systemic sclerosis-1980 were examined by conventional chest x-ray (CXR) at Tikrit teaching hospital,(2007-2008) . After that, each patient was subjected to chest HRCT. The finding in HRCT imaging seen in nine patients (90%), while only five patients (50%) showed an abnormality on conventional CXR suggestive of an interstitial lung disease and/or chronic pulmonary fibrosis. The HCRT findings were distributed among the reticular and nodular structures (70%), decreased opacity (70%) and other accompanying lesions seen in (60%) of patients. No one of the examined group showed a sign of increased opacity which include the sign of ground glass appearance. HRCT scanner considered a worthfull imaging modality in all patients with SSc, especially at an early stage of the disease as the management of the pulmonary complication in such patients is more effective when applied early

This study was done to assess the ability of high resolution computed tomography (HRCT) in detecting the early signs of pulmonary involvement in patients with systemic sclerosis (SSc). The chest in ten patients with established diagnosis of SSc according to American College of Rheumatology criteria for classification of systemic sclerosis-1980 were examined by conventional chest x-ray (CXR) at Tikrit teaching hospital,(2007-2008) . After that, each patient was subjected to chest HRCT. The finding in HRCT imaging seen in nine patients (90%), while only five patients (50%) showed an abnormality on conventional CXR suggestive of an interstitial lung disease and/or chronic pulmonary fibrosis. The HCRT findings were distributed among the reticular and nodular structures (70%), decreased opacity (70%) and other accompanying lesions seen in (60%) of patients. No one of the examined group showed a sign of increased opacity which include the sign of ground glass appearance. HRCT scanner considered a worthfull imaging modality in all patients with SSc, especially at an early stage of the disease as the management of the pulmonary complication in such patients is more effective when applied early

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