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Assessment of Endometrial Thickness in Postmenopausal Women with and without Hypertension

Author: Nada Salih Amen
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2012 Volume: 11 Issue: 1 Pages: 39-44
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT :BACKGROUND:Hypertension in postmenopausal women is a risk factor for endometrial hyperplasia.OBJECTIVE:To examine whether the endometrium of hypertensive postmenopausal women is thicker than thatof non hypertensive postmenopausal women, to determine whether this thickening is directlyrelated to the antihypertensive drugs and whether is associated with abnormal pathology.METHODS:A Case control study of Forty five hypertensive asymptomatic postmenopausal women wasconducted in Al Yarmouk Teaching Hospital, (22) were treated with B- blockers combinationmedication and (23) were treated with other medications. They were compared with each and with(25) non hypertensive women. All women were interviewed; blood tests were performed andendometrial thickness in antero-posterior diameter was measured by vaginal ultrasonography.Endometrial sampling had been taken for those with increased endometrial thickness more than5mm.RESULTS:24.44% of hypertensive women and 4.00% of non hypertensive women had an endometrialthickness more than 5mm. There was no statistically significant difference between those whotreated with medication including B- blocker and those who were treated with other medication.The histological findings were mainly of endometrial hyperplasia for those with thickenedendometrium.CONCLUSION:Hypertension may have a role in endometrial thickness. We were unable to substantiate anassociation between the type of treatment administered and the increase in endometrial thickness.Those with increased endometrial thickness more than 5mm, the histological findings were mainlyof endometrial hyperplasia

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