research centers


Search results: Found 27

Listing 1 - 10 of 27 << page
of 3
>>
Sort by

Article
Assessment of The Nurses’ Knowledge about Skin Care For Patients Undergo Radiotherapy of Breast Cancer at Al –Amal National Hospital for Cancer Management in Baghdad City
تقييم معارف الممرضين حول العناية الجلدية للمرضى الخاضعين للعلاج الاشعاعي لسرطان الثدي في مستشفى الأمل الوطني لعلاج السرطان في مدينة بغداد

Author: Wafaa M. Atoof Al-Attar
Journal: kufa Journal for Nursing sciences مجلة الكوفة لعلوم التمريض ISSN: 22234055 Year: 2015 Volume: 5 Issue: 1 Pages: 119-127
Publisher: University of Kufa جامعة الكوفة

Loading...
Loading...
Abstract

Objectives: The study aims to identify the nurse’s knowledge toward skin care for patients undergo radiotherapy breast cancerMethodology: Seventy nurses were selected to achieve the objectives of the study. The study was conducted during Feb./2014 at Al –Amal National Hospital for Cancer Management in Baghdad City. The questionnaire consists of two parts first part: included demographic characteristics of the nurses and the second part: included clauses relating to the knowledge of nurses about skin care to patients undergoing radiation therapy consisted of (20) items .Data were analyzed by using Frequency, percentage and chi-squared test. Results: The study results showed that most of nurse’s Knowledge was range between low(40%) and moderate(45.7%)and there were significant differences between nurse’s knowledge and nurse’s variables age, level of education, years of experience in radiotherapy unit and number of training sessions at (p<0.05).Conclusion: The researcher concluded that the nurse’s knowledge is insufficient about skin care for patients undergoing radiotherapy of breast cancer.Recommendation: It is recommended increase the researcher to focus on the nurses knowledge about skin care for patients undergoing radiotherapy of breast cancer and to identify the symptoms of the side effects of radiation therapy and prevention.

الهدف: تهدف الدراسة إلى التعرف على معارف الممرضين تجاه العناية الجلدية لمرضى سرطان الثدي الخاضعين للعلاج الإشعاعيالمنهجية : تم اختيار سبعون ممرض وممرضة للتحقيق اهداف الدراسة. واجريت الدراسة خلال شهر شباط/ في مستشفى الأمل الوطني لعلاج السرطان في مدينة بغداد. ويتألف الاستبيان من محورين المحور الاول تضمن الصفات الديموغرافية للممرضين والمحور الثاني تضمن فقرات تتعلق بمعارف الممرضين حول العناية بالجلد للمرضى الخاضعين للعلاج الاشعاعي وتكونت من (20) فقرة وقد تم تحليل البيانات باستخدام التكرارات، والنسبة المئوية والمتوسط الحسابى واختبار مربع كاىالنتائج: اظهرت نتائج الدراسة أن معظم معارف الممرضين تراوحت مابين منخفضة (40٪) ومتوسطة (45.7٪)،وتبين وجود فروق ذات دلالة إحصائية بين معارف الممرضين ومتغيرات العمر، ومستوى التعليم، وسنوات الخبرة في وحدة العلاج الإشعاعي وعدد الدورات التدريبية بمستوى معنوية (P<0.05).الاستنتاج: استنتج الباحث بان معارف الممرضين غير كافية حول العناية بالجلد لمرضى سرطان الثدي الخاضعين للعلاج الإشعاعيالتوصيات: يوصى الباحث بزيادة التركيز على معارف الممرضين من خلال دورات تتعلق بكيفية العناية بالجلد لمرضى سرطان الثدي الخاضعين للعلاج الإشعاعي وتحديد الاعراض من التاثيرات الجانبية للعلاج الاشعاعي والوقاية منه.


Article
Impact of tumor biomarkers and patient’s age on the “disease stage” in women with breast cancer in Erbil city
تأثير المؤشرات الحيوية للورم وعمر المريض على "مرحلة المرض" عند النساء المصابات بسرطان الثدي في مدينة أربيل

Authors: Jangi Sh. Muhialdin --- Showan Salam Marouf
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2015 Volume: 19 Issue: 2 Pages: 1019-1028
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

Loading...
Loading...
Abstract

Background and objective: Female breast cancer is the most commonly diagnosed cancer worldwide, affecting more than one million women annually. The objectives of this study were, firstly, to evaluate the effects of breast cancer biomarkers such as human epidermal growth factor receptor-2and hormone receptor status on the stage of breast cancer at the time of presentation, and secondly, to assess the role of “women’s age” on the level of biomarker expressions and on the advancement in breast cancer disease stage at the time of diagnosis in a sample of women diagnosed with breast cancer in Erbil City. Methods: A retrospective analysis of medical records of women affected with breast cancer was performed from January 2013 to April 2014. Cancer staging was done based on the histopathological reports according to the American Joint Committee on Cancer TNM staging system. Patients were classified to either hormone receptor/human epidermal growth factor receptor-2 positive or negative based on immunohistochemistry or FISH analysis. Results: The mean age (+SD) at diagnosis was 48.9 (+12.4) years. About a quarter of breast cancer cases were diagnosed in young women aged less than 40 years, who had a proportionally more hormone receptor negativity and human epidermal growth factor receptor-2 over-expression, and a significantly more advanced cancer stage at time of diagnosis compared to their older counterparts.Conclusion: Breast cancer biomarkers have huge impacts on disease stage, and are greatly affected by age of women at time of diagnosis of breast cancer.


Article
THE INCIDENCE OF BREAST CANCER IN EXAMINED BIOPSIES OF BREAST MASSES IN AL-HUSSAIN TEACHING HOSPITAL IN KERBALA

Authors: Akram F.M. Ali اكرام فؤاد محمد علي --- Anees K. Nile انيس خليل نايل --- Fatin H.A. Al-Wajidi فاتن جاسم علي
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2015 Volume: 13 Issue: 1 Pages: 97-102
Publisher: Al-Nahrain University جامعة النهرين

Loading...
Loading...
Abstract

Background:Breast cancer is the most common type of malignancy among females worldwide. Breast cancer is the second most commonly diagnosed cancer in women under 35 years with the most common hitological type being infiltrative ductal carcinoma.Objective:To determine the incidence of breast cancer in excised breast biopsy specimen in Al-Hussain Teaching Hospital in Kerbala governorate as well as determining the most prevalent histopathological type, pathological stage and grade at time of diagnosis.Methods:It was a statistical study in which a total of 200 excised biopsy and mastectomy specimens where enrolled in the study, biopsy processing and slide preparation from paraffin blocks was processed in the pathology laboratory in Al-Hussain teaching hospital in Kerbala from January 2011 – January 2012.Results:Out of 200 cases who were initially enrolled in the study, 140 (70%) were benign, and 60 (30%) were malignant. The highest incidence of breast cancer was found among 40-49 years age and ductal carcinoma is the most common histological type.Conclusions:Breast cancer accounts for about 30% from all excused biopsy materials in Al-Hussain Teaching Hospital in Kerbala. This study highlights some of the features of breast cancer seen in this region; younger age, intermediate stage at presentation, and higher incidence in housewives. In contrast to data from the West, where more than half of breast cancer patients are above 50 years of age and higher incidence among high socioeconomic group.Key words:Breast cancer, lesions, histopathology, incidence, percent.


Article
Surgical –Audit on breast cancer risk factors in AL-Russafa district in Baghdad

Author: Rasim D. Ajoob*, Harith S. Hassani**, Jamal R. Abudlhameed *
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2015 Volume: 11 Issue: 1 Pages: 73-77
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Breast cancer remains a substantial cause of morbidity and mortality, there is a need for continued efforts to understand the etiology of the disease, maintain screening effort, implement prevention strategies, and develop better treatments.Objective: To analyze the risk factors, improve early detection and prevention of breast cancer in Al-Russafa district- Baghdad, aiming to increase survival rate and improve the quality of life.Methods: A cross sectional audit of 258 breast cancer cases seen at Al-Elwiya maternity teaching hospital from January2009 to December 2011,data collected from patients files were: age, gender , residency, marital status, parity, age at menarche and menopause age at first live birth, hormonal therapy, social habit, previous breast diseases, breast feeding and family history of breast cancer.Results: Two hundred fifty eight female diagnosed with breast cancer, age ranging from 20 to 79 years. Breast cancer was more prevalent in the fourth and fifth decade of life. The distribution was according to residency sectors, 10% were unmarried; fourteen percent nultiparous, the age at menarche was prevalent in 12 and 13 years old. Menopa-ausal age was at the fifth decade and age of patients at first live child at twenties. Forty two % received contraceptive hormonal therapy, 15% had previous breast diseases, 20% with family history of breast cancer, 24% non-breastfeeding and 6% smokers.Conclusion: Risk factors of breast cancer in Baghdad is a perplexing issue and needs a privy analysis as the disease has a para amount importance with increasing incidence in last decade. Knowing the risk factors for breast cancer may help us take preventive measures to reduce the likelihood of developing the disease and develop better treatment.Keywords: Breast cancer, Risk factors, surgical audit.Background: Breast cancer remains a substantial cause of morbidity and mortality, there is a need for continued efforts to understand the etiology of the disease, maintain screening effort, implement prevention strategies, and develop better treatments.Objective: To analyze the risk factors, improve early detection and prevention of breast cancer in Al-Russafa district- Baghdad, aiming to increase survival rate and improve the quality of life.Methods: A cross sectional audit of 258 breast cancer cases seen at Al-Elwiya maternity teaching hospital from January2009 to December 2011,data collected from patients files were: age, gender , residency, marital status, parity, age at menarche and menopause age at first live birth, hormonal therapy, social habit, previous breast diseases, breast feeding and family history of breast cancer.Results: Two hundred fifty eight female diagnosed with breast cancer, age ranging from 20 to 79 years. Breast cancer was more prevalent in the fourth and fifth decade of life. The distribution was according to residency sectors, 10% were unmarried; fourteen percent nultiparous, the age at menarche was prevalent in 12 and 13 years old. Menopa-ausal age was at the fifth decade and age of patients at first live child at twenties. Forty two % received contraceptive hormonal therapy, 15% had previous breast diseases, 20% with family history of breast cancer, 24% non-breastfeeding and 6% smokers.Conclusion: Risk factors of breast cancer in Baghdad is a perplexing issue and needs a privy analysis as the disease has a para amount importance with increasing incidence in last decade. Knowing the risk factors for breast cancer may help us take preventive measures to reduce the likelihood of developing the disease and develop better treatment.


Article
Relationship between estrogen hormone as risk factor and development of breast and endometrial cancer

Author: Liqaa Y.Abed.Alrahman لقاء عبدالرحمن
Journal: The Medical Journal of Tikrit مجلة تكريت الطبية ISSN: 16831813 Year: 2015 Volume: 20 Issue: 1 Pages: 40-47
Publisher: Tikrit University جامعة تكريت

Loading...
Loading...
Abstract


Article
Salivary tumor marker CA15-3 and selected elements in relation to oral health status among a group of breast cancer women

Authors: Basma Abdul Bari Azeez بسمة عبد الباري عزيز --- Ahlam T. Mohammed
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2015 Volume: 27 Issue: 3 Pages: 124-129
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Breast cancer is the commonest type of malignancy worldwide and in Iraq. It is a serious disease thataffects the general health and cause systemic changes that affect the physical and chemical properties of salivaleading to adverse effects on oral health. This study was conducted to assess the tumor marker CA15-3 and selectedelements in saliva and their relation to oral health status among breast cancer patients compared to control group.Materials and Methods: The total sample consisted of 60 women aged 35-45 years. 30 women were newly diagnosedwith breast cancer before taking any treatment and surgery (study group) and 30 women without clinical signs andsymptoms of breast cancer as a control group. Dental caries was recorded using DMFS index of WHO1987, andperiodontal parameters which include plaque index (PlI), calculus index (CalI), gingival index (GI), and Ramfjodindex for the loss of periodontal attachment (CAL) were recorded. Stimulated salivary samples were collected andsalivary flow rate, salivary CA15-3 and selected elements were determined.Results: Caries experience (DMFS) was higher among the study group compared with the control group but thedifference was statistically not significant. The mean values of plaque index, calculus index, gingival index and loss ofattachment were higher among the study group than the control group with a highly significant difference(P<0.01).The concentrations of the tumor marker CA15-3 in saliva of breast cancer patients were highly significantly higherthan that of the controls. The salivary flow rate was observed to be lower among study group compared to controlgroup with a highly significant difference (P<0.01). Higher concentrations of salivary phosphorus, copper and totalproteins were recorded among study group compared to control with statistically highly significant differencesconcerning phosphorus and copper. While salivary calcium and zinc were lower among study group compared tocontrol group with statistically highly significant difference concerning zincConclusions: This study showed that the breast cancer patients had poor oral hygiene and higher rates ofperiodontal diseases and dental caries. In addition, the results of this study could support the concept that salivaryconcentrations of CA15–3 might serve to be used in the detection of breast cancer and/or the post-operative followupof patients under treatment for carcinoma of the breast

Keywords

Breast cancer --- Oral health --- CA15-3.


Article
Breast Cancer: Knowledge ,Attitudes and Practices of Female Secondary Schoolteachers and Students in Samarra City
سرطان الثدي: المعارف والمواقف والممارسات لدى مدرسات وطالبات المدارس الثانوية في مدينة سامراء

Authors: Balqees Ramadan Abass بلقيس رمضان عباس --- Abid Ahmed Salman عبد أحمد سلمان
Journal: Iraqi Journal of Cancer and Medical Genetics المجلة العراقية للسرطان والوراثة الطبية ISSN: 20786123 Year: 2015 Volume: 8 Issue: 1 Pages: 52-59
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

This is a cross-sectional, questionnaire-based study evaluated the knowledge, attitude and practice towards breast cancer and breast self-examination (BSE) among 225females (125 schoolteachers &100 students) in female secondary schools in Samarra City, from November 2013 to March 2014.The result of the study indicated that majority of female had better knowledge level about breast cancer and (BSE) but with bad practice. Television was most reported source of information on breast cancer and (BSE) mentioned by the respondents. The knowledge of the respondents about breast cancer was assessed and scored. The most reported correct answer about breast cancer symptoms was painless lump for schoolteachers 84.8% and change in breast shape for students 88%.Radiation was the most known risk factor in all 100% of teachers ,while the most known one in students was smoking 99%.In spite of about 73.3% of participants had heard about BSE ,only 27.6% of them practiced it even at irregular intervals.67.7%of them are of high knowledge level and 32.3%are of moderate level. This study demonstrated that majority of respondents were aware of breast cancer as a disease entity, but their practice toward breast self examination was poor. Accordingly, relevant educational programs to improve the practices of females regarding (BSE) are needed and qualitative researches to recognize the factors effective in the improvement knowledge and practices of breast cancer screening methods among these females are necessary.

هذه الدراسة المقطعية ,أساسها استبياني قيمت المعارف والمواقف والممارسات تجاه سرطان الثدي والفحص الذاتي للثدي أجريت لدى 225 أنثى (125 معلمة و100 طالبة) في كل المدارس الثانوية للبنات في مدينة سامراء من تشرين الثاني 2013 لغاية آذار 2014 إن نتائج الدراسة أشارت إلى إن أغلبية الإناث لديهن مستوى معرفة أفضل حول سرطان الثدي والفحص الذاتي للثدي لكن مع ممارسة سيئة . التلفزيون كان المصدر الأكثر تسجيلا للمعلومات عن سرطان الثدي والفحص الذاتي للثدي ذَكرَ مِن قِبل المستجيبات. معرفة المستجيبات حول سرطان الثدي تم تقييمها و تصنيفها. الجواب الصحيح الأكثر ذكرا حول أعراض سرطان الثدي كان كتلة غير مؤلمة للمدرسات 84,8% وتغيير شكل الثدي للطالبات 88% .ألإشعاع كان عامل خطورة الأكثر معروفا في كل 100% المدرسات ,بينما الأكثر معروفا في الطالبات كان التدخين 99%. بالرغم من إن نحو 73,3% من المشاركات قد سمعن عن الفحص الذاتي للثدي ,فقط 27,6% منهن يمارسنه حتى في فترات غير منتظمة. نحو 67,7% منهن لديهن مستوى معرفة عالي و 32,3% من مستوى معرفة متوسط . هذه الدراسة أظهرت إن أغلبية المشاركات كن مدركات لسرطان الثدي كوحدة مرض ,لكن ممارساتهم تجاه الفحص الذاتي للثدي كانت ضعيفة. وفقاً لذلك، برامج تربوية ذات العلاقة لتطوير ممارسات الإناث حول الفحص الذاتي للثدي مطلوبة وبحوث نوعية لتمييز العوامل الفعالة في تطوير معرفة وممارسات طرق فحص سرطان الثدي لدى هذه الإناث يعتبر ضروري.


Article
Best Way to Detect Breast Cancer by UsingMachine Learning Algorithms
أفضل طريقة لأكتشاف سرطان الثدي بأستخدام خوارزميات تعليم الالة

Author: Nahla Arabi Hamdo نهلة عربي حمدو
Journal: Iraqi Journal of Science المجلة العراقية للعلوم ISSN: 00672904/23121637 Year: 2015 Volume: 56 Issue: 2C Pages: 1794-1799
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Breast cancer is the second deadliest disease infected women worldwide. For this reason the early detection is one of the most essential stop to overcomeit dependingon automatic devices like artificial intelligent. Medical applications of machine learning algorithmsare mostly based on their ability to handle classification problems, including classifications of illnesses or to estimate prognosis. Before machine learningis applied for diagnosis, it must be trained first. The research methodology which isdetermines differentofmachine learning algorithms,such as Random tree, ID3, CART, SMO, C4.5 and Naive Bayesto finds the best training algorithm result. The contribution of this research is test the data set with missing value and without missing value, where the missing value is one attribute is missing from one sample for data set. The test result is show SMO is the best algorithm, especiallywhen the research removes the samples that contained the missing value.

سرطان الثدي هو ثاني أخطر مرض يصيب النساء في جميع أنحاء العالم. لهذا السبب الكشف المبكر هو واحد من المحطات الأكثر أهمية للتغلب عليه اعتمادا على الأجهزة الآلية مثل الذكاء الصناعي. التطبيقات الطبية في خوارزميات تعليم الآلة تعتمد في الغالب على التعامل مع مشاكل التصنيف، بما في ذلك التصنيفات للأمراض أو لتقدير او التكهن. قبل تطبيق التشخيص، يجب تدريب الالة اولا. وفي هذا البحث يتم استخدام منهجية البحث لخوارزميات مختلفة مثلا Random tree و ID3و CARTو SMOو C4.5 و Naive Bayes لإظهار أفضل نتيجة لتدريب الخوارزمية. المساهمة العلمية في هذا البحث هو اجراء الاختبار على مجموعة بيانات يوجد ضمنها عينات احد عناصرها مفقود ثماجراء الاختبار بعد حذف تلك العينات. نتيجة التجربة تظهر ان SMOهو أفضل خوارزمية خاصة عند ازالة العينات التي تحتوي على القيم المفقودة.


Article
Human Papilloma Virus 16 Survey in Breast Epithelium of Women Using In Situ Hybridization Technique

Authors: Mahmoud Mishaal Mohamed --- Huda Mahdi Al-Khateeb --- Khitam Razzak Kadhim Al-Khafaji***
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2015 Volume: 14 Issue: 3 Pages: 337-343
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND:There is increasing evidence that high-risk human papilloma virus (HPV) is involved in cancers other than cervical cancer. A number of reports have identified HPV DNA in breast tissue and breast cancer specimens, suggesting that the virus could play a role in the pathogenesis of this tumor. OBJECTIVE:The aim was directed towards the use of In situ molecular methods to localize the virus in breast tissue. In addition, this study investigated the prevalence of high-risk HPV infections in Iraqi women with and without ductal carcinoma (DC) of the breast. PATIENTS AND METHODS:29 cases of ductal carcinoma and 44 controls obtained from adjacent area to benign breast. Formalin fixed, paraffin embedded specimens were used by In situ hybridization technique for detection of HPV16 subtype. Data analysis was performed by SPSS 20 software using descriptive statistics and Chi-square tests.RESULTS:The HPV16 were identified in 69% and 27.3% of the ductal carcinoma and control breast tissue specimens respectively. Statistically, the difference between the normal and ductal carcinoma cases were highly significant (P=0.001). CONCLUSION:HPV16 In situ hybridization revealed statistically significant increase in DC (69%) as compared to controls (27.3%) and most of them were localized in the nuclei in integrative form. HPV16 were detected in skin and mammary tissue in both DC an control cases. This may indicates a role of HPV16 in the pathogenesis of DC.


Article
Immunohistochemical Expression of Hypoxia-Inducible Factor-1α in Triple Negative Breast Cancer

Authors: Mahdi Jassim Muhammad Ali --- Haider Abdul Ridha AL-Khafaji --- Abbas Fadhil Hassoon
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2015 Volume: 12 Issue: 4 Pages: 902 -915
Publisher: Babylon University جامعة بابل

Loading...
Loading...
Abstract

Triple-negative breast cancer is a malignant neoplasm characterized by absent expression of estrogen, progesterone and human epidermal growth factor-2 receptors. Hypoxia-inducible factor-1 alpha is up-regulated under hypoxia and associated with induction of angiogenesis resulting in proliferation, aggressive tumor phenotype and metastasis. Determination of the potential role of Hypoxia-inducible factor-1 alpha in the development and conventional clinicopathologic factors, and to demonstrate their prognostic relevance in Triple-negative breast cancer. A pro and retrospective study of 281 female patients with breast cancer. The fifty four triple-negative breast cancer formalin-fixed, paraffin-embedded Specimenspresented from all cases were immuno-stained by Hypoxia-inducible factor-1 alpha Immunohistochemical marker. The age groups distributed from 23-85 years old, mean age 51.23±11.26 years. Overall cases, triple negative breast cancer presented in 19.2%; most frequently younger,grade III, tumor size ≥ 2 cm, and positive lymph node metastasis or recurrent more than other subtypes. Hypoxia-inducible factor-1 alpha expression was strongly associated and significantly differentwith grade (p=0.001), lymph node metastasis (p<0.001) and Ki-67 expression (p=0.003). Detected Hypoxia-inducible factor-1 alpha expression has an important role in pathogenesis, drug resistance and in uncontrolled proliferation cells or as important conductor of the worst prognosis in triple negative-breast cancer.

Listing 1 - 10 of 27 << page
of 3
>>
Sort by
Narrow your search

Resource type

article (27)


Language

English (23)

Arabic (2)

Arabic and English (1)


Year
From To Submit

2015 (27)