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Article
Gastric Malignancies and the Trend of Gastric Carcinoma in Duhok City-Iraq

Authors: Alaa Hani Raziq --- Sefar Mohammed Haj --- Sardar Hassan Arif --- Odeesh Yuhanna Odeesh
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2017 Volume: 14 Issue: 1 Pages: 162 -168
Publisher: Babylon University جامعة بابل

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Abstract

Gastric cancer is one of the common human malignancies particularly gastric adenocarcinoma. The stomach also represents the commonest gastrointestinal site for extra-nodal non-Hodgkin’s lymphoma. This study aims to find out the major types of gastric malignancies in Duhok city, their age and gender distribution and the trend of the types of gastric adenocarcinoma over a six year period from January 2008 till December 2013. This study included nearly all cases of gastric malignancies diagnosed in Duhok City and enrolled 155 cases. The type of malignancy was diagnosed by histopathological examination and supported in some cases by immunohistochemical staining procedures and investigations. The trend of the two major types of gastric carcinoma was determined over this six year period. The results of this study showed that the carcinoma constitutes the largest proportion of gastric malignancies (87.7%), followed by lymphoma (6.5%), then Gastrointestinal stromal tumor (GIST) (4.5%) and lastly neuroendocrine tumors (1.3%). The mean age of the intestinal type (62.1 years) was higher than that of the diffuse type (50.15 years) and the difference was statistically significant (P: < 0.05). Similarly the diffuse type was more common in women than men and also the difference was statistically significant (P: < 0.05). The results of this study show that the trend of intestinal type over a six year period is on the rise side while the trend of the diffuse type is more or less the same. Gastric carcinoma is the most common gastric malignancy in Duhok City with a male predominance and most patients had some bad prognostic factors and there is no decline in the prevalence of the intestinal type.


Article
Experience Of Gastric Cancer In Al- Sadder City in Baghdad

Author: Maytham Hatam Shahid, Saad Ramadan Jawad, Asaad Abdullah Abbas
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2017 Volume: 16 Issue: 2 Pages: 129-137
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND: The aim of the study is to assess the following points among the patients with gastric cancer admitted to the surgical wards in Imam Ali Hospital- Al- Sadder City- Baghdad.•Sex and age distribution. •Mode of presentation.•Results of endoscopic findings and histopathology.•Risk factors and tumour staging.•Treatment options.PATIENTS AND METHODS:A prospective study was done in Imam Ali Hospital for a period of six years from (January 2009 to December 2014) where fifty cases with biopsy proved gastric cancer had been assessed. The age and sex distribution, mode of presentation, site of the tumour, macrosopical appearances histopathological findings, risk factors and treatment options were analysed.RESULTS: The male to Female ratio was 1.4:1, peak age incidence was 60-70 years, non-specific symptoms such as vague epigastric pain, dyspepsia, anorexia, weight loss were the most common symptoms; esophagogastric junction was the commonest site, polypoid type was the commonest endoscopic finding (44%); upper gastrointestinal endoscopy with biopsy was the most accurate method of diagnosing gastric cancer; Adencarcinoma was the most frequent histopathological type (96%); cigarette smoking is the predominant risk factor (64%) (32, 33, 34, 35); In the majority of those patients the disease was advanced and the curative measures were not possible.CONCLUSION: Gastric cancer remains a significant problem in Iraq, it's one of the most popular malignancies (ninth most common in Iraq) (37). No age group of both sexes can be excluded. Late presentation is a stigmata of the disease and the gloomy prognosis can only be improved by early detection based on a more vigorous diagnostic approach following a high risk index of suspicion in individuals at risk.


Article
COMPARATIVE STUDY BETWEEN STAPLER AND HAND SEWING IN GASTROINTESTINAL ANASTOMOSIS

Authors: Mustafa Adnan Maatooq --- ssam Merdan
Journal: Basrah Journal of Surgery مجلة البصرة الجراحية ISSN: 16833589 / ONLINE 2409501X Year: 2017 Volume: 23 Issue: 2 Pages: 21-25
Publisher: Basrah University جامعة البصرة

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Abstract

COMPARATIVE STUDY BETWEEN STAPLER AND HAND SEWING IN GASTROINTESTINAL ANASTOMOSIS Mustafa Adnan Maatooq* & Issam Merdan@*MB,ChB, Board candidate, Al-Sadir Teaching Hospital, Basrah. @MB,ChB, FICMS, CABS, Professor of Surgery, Department of Surgery, College of Medicine, University of Basrah, IRAQ.AbstractGastrointestinal anastomosis is an important part of gastrointestinal operations and can be achieved by hand sewn anastomosis or by the newly developed staplers.The study aims to compare between the two surgical methods of anastomosis in a prospective , randomized design, regarding: operation time, post operative hospital stay and the incidence of post operative anastomotic leak in both groups. The study was carried out in Department of Surgery at Alsader Teaching Hospital in Basrah, Iraq from October 2015 to December 2016, it included 40 patients of both gender and with a different age, they divided into 2 groups (hand sewn and stapler groups), each group included 20 patients, comparing the following parameters: time of anastomosis, duration of surgery, post operative leak and hospital stay.There were no significant differences in the age, gender distribution, the indication for resection, post operative anastomotic leak (p=1) and hospital stay (P Value 0.15 ) in both group but there was significant differences in duration of anastomosis (P Value0 .00001) and operation time (P Value 0.00001). Our study concluded the superiority of stapler on hand sewing in gastrointestinal anastomosis in term of reducing operative time.


Article
Detection of, cagA and vacA Helicobacter pylori Virulence Genes in Gastric Biopsies of Patients with Gastroduodenal Disease using Polymerase Chain Reaction (PCR) Technique
التحري عن جينات ضراوة البكتريا الحلزونية ureA, cagA and vacA في خزعات نسيجة من معدة مصابين بأمراض المعدة والاثني عشر باستخدام تقنية تفاعل الكوثرة (PCR)

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Abstract

The objective of current study was to detect the prevalence of Helicobacter pylori by identifying 16SrDNA and to determine the virulence genes (ureA, cagA and vacA) in biopsy specimens from patients suffering gastroduodenal disease using polymerase chain reaction (PCR). Forty samples were obtained by gastroenterologists during endoscopy from gastric antral of suspected individual attending endoscopy unit at Baqubah Teaching Hospital, Diyala, Iraq, during the period from September 2015 to February 2016. According to the endoscopic finding the patients were allocated into four groups of gastroduodenal diseases and control, which include gastritis (GS), duodenal ulcer (DU), gastric ulcer (GU), gastric cancer (GC), their rates were 30% (12), 20% (8), 17.5% (7), 7.5% (3) and 25% (10), respectively. DNA was extracted from the biopsies and subsequently used for PCR detection of H. pylori and the virulence genes using specific primers. The results shows that 60% of samples were positive for H. pylori, of these positive samples, 91,66%, 66.66%, and 48.83%, were shown to have the virulence genes, ureA, cagA, and vacA, respectively. It is important to mention that cagA shown the highest prevalence rate in gastric cancer cases in comparison with vacA gene. further studies are required to study the link between cagA gene and gastroduodenal diseases. In conclusion the result of present study provide important information concerning the prevalence of virulence genes of H. pylori.

هدفت الدراسة الاستدلال على وجود البكتيريا الحلزونية Helicobacter pylori بالكشف عن المورث مشفر الرنا الرايبوسومي 16أس (16SrDNA) وتحديد امتلاك هذه البكتريا لمورثات الفوعة: المورث المشفر للوحدة A من انزيم اليوريز (ureA gene) و المورث المقترن بالسمية الخلوية cagA ومورث تشفير سم التحوصل الخلوي vacA ، في عينات خزعة النسيج من مصابين بأمراض المعدة والاثني عشر باستخدام تفاعل سلسلة أنزيم الكوثرة (PCR). جمعت أربعين خزعة نسيجية بأشراف طبيب الجهاز الهضمي خلال التنظير من غار المعدة من مرضى محالين لوحدة الناظور في مستشفى بعقوبة التعليمي/ ديالى-العراق، خلال الفترة من سبتمبر 2015 إلى فبراير 2016. وفقا لفحص المنظار توزع المرضى الى اربع مجاميع مرضية ومجموعة ضابطة، ضمت التهاب المعدة (GS) وقرحة الاثني عشر (DU)، وقرحة المعدة (GU)، وسرطان المعدة (GC) ، شكلت نسبها 30٪(12)، 20٪ (8) و 17.5٪(7)، 7.5٪(3) و 25٪ (10)على التوالي. استخلص الحمض النووي الريبوزي منقوص الاوكسجين من خزعات النسيج وكشف عن البكتيريا وعن مورثات الفوعة بتقنية تفاعل سلسلة أنزيم الكوثرة PCR باستخدام بادئات محددة. بين الكشف ان 60٪ من خزعات النسيج في الأمراض المذكورة أعلاه موجبة للبكتريا الحلزونية، وكانت معدلات تواجد مورثات الفوعة في العينات الموجبة 91.66٪ و 66.66٪ و 48.83٪ للمورثات ureA gene و cagA gene و vacA gene على التوالي. ومن الأهمية بمكان الإشارة الى ان المورث cagA gene أعطى أعلى نسبة في حالات سرطان المعدة مقارنة بالمورث vacA gene، وخلص إلى احتمال ارتباط المورث بالمرض. ان هذه الدراسة توفر معلومات هامة بشأن انتشار مورثات فوعة البكتريا الحلزونية.


Article
Comparative Physiological and Anatomical and Histological study of parts of Gastroitestinal Tract Between Chicken (Gallus gallus) , Geese (Anserini domestica) and Racing Pigeon (Columba livia domestica)
دراسة فسلجية تشريحية ونسجية مقارنة لأجزاء من القناة الهضمية بين الدجاج (Gallus gallus) والاوز المحلي (Anserini domestica) والحمام الزاجل (Columba livia domestica

Author: Ahmed J. Al-yasery, أحمد جواد الياسري
Journal: Jornal of Al-Muthanna for Agricultural Sciences مجلة المثنى للعلوم الزراعية ISSN: 40862226 Year: 2017 Volume: 5 Issue: 1 Pages: 91-101
Publisher: Al-Muthanna University جامعة المثنى

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Abstract

This study was carried out in the laboratories of Agriculture college, Al-Muthanna University to investigate the comparative anatomical and histological structures of gastrointestinal tract in three species of avian (local poultry, local Gees and Pigeon), A18 birds was used, in which they were divided into 6 birds for each group. The anatomical results in poultry, geese and pigeon revealed that they possesses swallowing crop numerous mucous glands. In pigeon, swallowed crop was connected with muscular part of esophagus (10-15cm) length to form crop and proventriculus, which is a thick swallowing wall of conical shape. The results showed that poultry revealed significant superiorities at (P≤0.05) over geese and pigeon in anatomical dimensions of crop and gizzard, while poultry and pigeon revealed significant superiorities at (P≤0.05) over geese in proventriculus weight, length and thickness, the poultry and geese revealed a significant superiority over pigeon, while in width, the poultry revealed significant superiority on geese and pigeon

أُجريت الدراسة الحالية في مختبرات كلية الزراعة / جامعة المثنى للتعرف على التركيب التشريحي والنسيجي لأجزاء من القناة الهضمية في الطيور المحلية حيث استخدم (18) طيراً من (الدواجن Local Poultry ، الأوز المحلي Local Geese والحمام الزاجل Racing pigeon). اظهرت النتائج التشريحية في الدواجن والاوز ان الحوصلة عبارة عن انتفاخ للقناة الهضمية تحتوي عدد كبير من الغدد المخاطية mucous glands ، والمعدة الغدية الحقيقية هي تركيب بيضاوى الشكل يصل الحوصلة بالقانصة تبطن بغشاء مخاطي ، والمعدة العضلية (القانصة) هي كتلة عضلية سميكة، بينما أظهرت النتائج التشريحية في الحمام أن الحوصلة تتصل مع الجزء العضلي للمرئ وطوله 10 - 15 سم الذي ينتفخ لتكوين الحوصلة، كما أظهرت النتائج ان الدجاج كان متفوقا معنويا (P ≤ 0.05 ) على الاوز والحمام في القياسات التشريحية للحوصلة والقانصة ، بينما يظهر الدجاج والحمام تفوقا معنويا (P ≤ 0.05 ) على الاوز بوزن المعدة الحقيقية ، وفي طول المعدة الحقيقية كان الدجاج والاوز متفوقان على الحمام ، وفي عرض المعدة الغدية كان الدجاج متفوقا على الاوز والحمام وفي السمك كان الدجاج والاوز متفوقان على الحمام .

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