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Article
Modulation Male Fertility in Diabetic Rats by Allicin Administration

Authors: Dr. Hazar Shakir Saleh --- Dr. Enaas Saleh Al- Kayat
Journal: Journal of Education for Pure Science مجلة التربية للعلوم الصرفة ISSN: 20736592 Year: 2017 Volume: 7 Issue: 1 Pages: 96-110
Publisher: Thi-Qar University جامعة ذي قار

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Abstract

Diabetes has been known to cause fertility complications including male reproductive organs failure and infertility. However, many studies have examined the anti-diabetic effect of major component of garlic compounds, allicin, in both types of diabetes mellitus (DM), but to date, the role of allicin in male fertility protection throughout disease process of diabetes mellitus remains unclear. Objective: Hence this study has been undertaken to evaluate histological changes via allicin administration in the maintenance male reproductive system function in rats-exposed to diabetes mellitus. Methods: Thirty adult male rats have been divided into three groups (10 rats in each group). The two control groups, including diabetic rats (DM induced by intraperitoneal injection with a single dose of Streptozocin (STZ) 65mg/kg body weight) and normal rats, which were injected with normal saline, once daily for 21 days. The third group received allicin. Blood glucose levels were tested every day through 21 days of the experimental period. At the end of the experiment, testis tissues were taken from the rats for histological examination and they were fixed in 10% neutral formalin solution and hematoxylin and eosin (H&E) stained sections of testis were prepared for histopathological and Histomorphometric examination under light microscope. Results: The results were compared to the ones obtained from healthy and non-treated diabetic rats as well as allicin -treated diabetic rats. Histopathological examinations of stained testicular tissue sections showed necrosis and vacuolization of spermatocytes to be reasonably reduced in the diabetic treated rats as well as demonstrated abnormal spermatogenises but it was found to restore the testicular histology and components of spermatogenises to near normal in the allicin treated group. Subsequent histomorphometrical evaluation also showed a reduction in the diameter and height epithelia of seminiferous tubules in the diabetic control rats which were significantly improved in the allicin- treated diabetic rats (P < 0.05) which were comparable to normal rats. Conclusion these results indicate that the active compound of garlic plant may help in the prevention of the complications of diabetes and confer essential protection for male reproductive function as serious complication.


Article
AZFc deletion assignment in fertile male

Author: Faculty of Medicine, Thi-Qar University
Journal: Iraqi Journal of Biotechnology المجلة العراقية للتقانات الحياتية ISSN: 18154794 Year: 2017 Volume: 16 Issue: 3 Pages: 230-234
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Infertility due to male factor, is considered as a major contributor in the prevalence picture of the infertility in the world. Spermatogenic process & its products are considered the backbone of male fertility. This process is directly related to the genes expression which are located on the long arm of Y-chromosome (Yq). These genes are occupy the three AZF (Azoospermia factors;AZFa,AZFb and AZFc) regions which proved to be a hot spot for deletion mutations. AZFc intervals deletion is the most prominent deletion with less penetrance that ranging from mild oligospermia to moderate oligospermia. To assess AZFc deletion correlation with male fertility status and to evaluate the rate of AZFc deletion within primary fertile males population. Cross sectional study was adopted to select 110 child fathering fertile males who are subjected for conventional infertility investigations and molecular genetic analysis (AZFc deletion). Sixteenth cases (16/110 (14.5%)) shows poor semen parameters (oligospermia) but with normal genetic analysis (no AZFc deletion). one case out of which (1/16 (6.25%)) complaining of secondary infertility. 5 cases (5/110(4.5%)) shows AZFc deletion with variable range of oligospermia. 4(4/5(80%) out of which complaining secondary infertility but with primary fertile status (fathering a child). Conclusion: These results denoting that, AZFc delation mostly associated with spermatogenic failure (oligospermia) but not necessarily with absolute male infertility.


Article
Effect of Fertility Blend® Administration on the Oocytes Quality and Embryonic Development using assisted Reproductive Technology in Mice
تأثير اعطاء خليط الخصوبة على نوعية البويضات والتطور الجنيني باستخدام تقنية مساعدة على الانجاب في الفئران

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Abstract

Female Fertility Blend ® (FFB) is one of new nutritional supplement that used to enhance the fertility status in women. This supplement containing vitamins, minerals, enzymes, amino acids, all may improve the oocytes quality and ovarian function; at the same time protect oocytes from free radicals damage. The aim of the study is to examine the in vivo effect of FFB on oocyte quality, and in vitro fertilization rate (IVFR), and embryonic development (ED) at early cleavage stages using the mice as a model for human being. Therefore, two groups of mature female mice were involved (20 mouse each). The treated group is daily orally administrated by 3.4mg/kg /body weight from FFB for 10 days and the other groups (the control) were treated with FFB- free distilled water only for the same period. Oocytes were collected and an epididymal sperms from mature fertilized male mice are obtained and in vitro fertilization (IVF) is done. Following 24 and 48hrs from IVF, the FR and ED rate are recorded. This results showed a significant (P<0.05) differences in fertilization rate and embryonic development when treating the female mice with FFB compared to control group. It is concluded that the FFB treatment has a great improvement in oocytes maturation and in vitro fertilization and embryonic development status.

يعد خليط خصوبة الاناث Female Fertility Blend ® (FFB) من المجهزات الغذائية الجديدة التي تستخدم في دعم الحاله الاخصابية للنساء. اذ يحتوي على الفيتامينات والمعادن والانزيمات والاحماض الامينية بمجموعها ربما تحسن من نوع البويضات ووظيفة المبايض وفي نفس الوقت تحمي البويضات من التاثيرات الهدامه للجذور الحرة. لذا هدف البحث هو فحص تاثير FFB على نوعية البويضات والاخصاب الخارجي والتطور الجنيني في مرحلة الانقسام المبكر باستخدام الفئران كموديل للانسان. وعليه هيئت اناث الفئران الناضجه وقسمت الى مجموعتين (20 فأر في كل مجموعه). اجري التجريع اليومي لمجموعة المعالجة 3.4 ملغم/كغم/وزن الجسم من FFB ولمدة 10 ايام في حين تم تجريع مجموعة السيطرة ماء مقطر فقط. جمعت البويضات من الاناث المعاملة واناث السيطرة وحصل على النطف البربخة من ذكور ناضجة خصبة واجري الاخصاب في الزجاج. بعد 24 و48 ساعة سجل معدل الاخصاب ومعدل تطور الاجنة. بينت نتائج الدراسة وجود فروقات معنويه (P<0.05) في معدل الاخصاب والتطور الجنيني في المجموعه التي عولجت بـ FFB بالمقارنه مع مجموعة السيطرة. نستنتج من الدراسة الحالية بان المعالجة FFB قد حسنت بشكل كبير من معدل نضوج البويضات والاخصاب وحالة التطور الجنيني.


Article
EFFECTS OF LAND AND WELL WATER EXPLOITATION IN FERTILITY CHARACTERIZATION IN ABUGRIB SOILS
استخدام الارض ونوعية ميــاه الابـار في الصـفـات الخصوبية لتــربة أبــي غريــب

Author: Farhan Mohammed Jassim Al - Thiabi فرحان محمد جاسم الذيابي
Journal: IRAQI JOURNAL OF DESERT STUDIES المجلة العراقية لدراسات الصحراء ISSN: pISSN: 19947801 / eISSN: 26649454 Year: 2017 Volume: 7 Issue: 1 Pages: 92-103
Publisher: University of Anbar جامعة الانبار

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Abstract

This study included knowing effects of land and well water exploitation in fertility characterization. The region of the study is characterized with dry climate and Level to nearly level slope. After field investigation about the nature of agricultural exploitation in the region as well as management method, four agricultural systems were chosen where their age not less than 10 years in order to get to the homogeny status in management manner. Five pidons were digged in study area. Soil samples were taken from each characterized horizon in order to study physical, chemical and fertility characterization while water samples, they were taken from wells water. The results showed the following: 1-The results showed that the EC for surface horizons which were used agriculturally between( 0.82 – 2.3 dS. m-1) while the surface. 2- The results showed tangible increase in soluble ion concentration of anions and cations in soil solution. The values of Calcium were between( 14 – 19.5 centimole charge kg-1) while magnesium values were between ( 6.9 – 11.4 centimole charge kg-1 ) while sodium values were( 6.3 – 19.2 centimole charge kg-1), potassium values were between (0.24 – 0.35 mg kg sol-1). Bicarbonate values were between (3.5 – 5.6 centimole charge kg-1) sulphate values (4.5 – 12.2 centimole chage kg-1) while chlorides values were between (17.7 – 29.3 centimole charge kg-1). 3-Available nitrogen in the study soils values were between (16.4 – 36.2 mg Kg soil-1), available phosphorus (13.95 – 43 mg Kg soil-1), available potassium (190.7 – 225 mg Kg soil-1), available iron (5.3 – 7.5 mg Kg soil-1) and available zinc (0.58 – 6.6 mg kg soil-1) and for all soils. 4-The results of the study showed that EC values for used in irrigation (well water) were between (2.2 – 4.30 dS. m-1) and pH (7.3 – 7.5). The values of SAR were between (1.6 – 4) and the classification of study water according to (USDA ,1954) was within (C3- S1)

تتضمن هذه الدراسة معرفة تأثير تنوع استغلال الارض ومياه الآبار على الصفات الخصوبية في بعض ترب ابي غريب . تتصف المنطقة بمناخ جاف وطوبوغرافية ذات انحدار قليل وبعد التحري الحقلي عن طبيعة الاستغلال الزراعي في المنطقة وطريقة ادارة التربة تم اختيار اربعة انظمة زراعية حيث لايقل العمر الزمني عن عشر سنوات لغرض الحصول على حالة تجانس في اساليب الادارة, ثم حفر خمس بدونات في منطقة الدراسة ثم استحصلت عينات مواد التربة من كل افق من الافاق المشخصة وعينات من خلال الاوكر لدراسة الصفات الخصوبية واخذت نماذج من مياه الابار لدراسة الصفات الكيميائية واوضحت النتائج ما يلي أظهرت نتائج الدراسة بان قيم الايصالية الكهربائية ECللآفاق السطحية في مستخلص التربة للمواقع المستغلة زراعيا تراوحت مابين (2.3 – 0.82 dS.m-1) ويلاحظ عدم وجود انتظام في ارتفاع وانخفاض قيم هذا المؤشر في ترب الدراسة. بينت النتائج ارتفاع ملموس في تركيز الايونات الذائبة الموجبة والسالبة في محلول التربة حيث تراوحت قيم الكالسيوم ما بين ( 14.0- 35سنتي مول شحنة . كغم-1) اما قيم ايونات المغنيسيوم فتراوحت بين ( 17.4 – 6.9 ملي مول .كغم-1) في حين بلغت قيم الصوديوم ( 19.2 – 6,3 ملي مول شحنة . كغم-1) اما البوتاسيوم فتراوحت بين ( 0.35 – 0.24 ملغ . كغم تربة -1) وتراوحت قيم ايون البيكاربونات مابين (5.6- 3.5سنتي مول . كغم -1) فيما تراوحت قيم ايونات الكبريتات بمدى ( 12,2 – 4.5 ملي مول شحنة .كغم -1) اما الكلوريدات فتراوح مداها مابين(25.3 – 17.7 ملي مول شحنة . كغم تربة -1) . تراوحت كمية عنصر النتروجين الجاهز في ترب الدراسة ما بين 36.2 – 16.4) ملغم . كغم تربة -1) وسجل الفسفور الجاهز كمية تراوحت ما بين ( 43 – 13.95 ملغم . كغم تربة -1) والبوتاسيوم الجاهز تراوحت كميته (225 – 190.7 ملغم . كغم تربة -1) اما الحديد الجاهز فتراوحت كميته مابين (7.5 – 5.3 ملغم . كغم تربة -1)بينما تراوحت كمية الزنك الجاهز مابين ( - 0.58 6.6 ملغم . كغم تربة -1) ولجميع ترب الدراسة . أظهرت نتائج الدراسة قيم التوصيل الكهربائي للمياه المستغلة لري المحاصيل (مياه آبار) فقد تراوحت ما بين ( 4.30 – 2.2 dS.m-1) ودرجة التفاعل بلغت ما بين (7.5 – 7.3) وإن قيمة SAR تراوحت مابين ( 4 – 1.6) وان تصنيف ألمياه في موقع الدراسة وفق مختبر ملوحة التربة الامريكي USDA) ,1954) تقع ضمن صنف (S1-C3).


Article
Positional contrast for fertility levels in Iraqi governorates in 1997-2007
التباين المكاني لمستويات الخصوبة في محافظات العراق للمدة 1997-2007

Author: DhiaaJa’far Abdul Zahra Al-Najm ضياء جعفر عبد الزهرة النجم
Journal: Adab Al-Kufa مجلة اداب الكوفة ISSN: 19948999 Year: 2017 Volume: ج2 Issue: 33 Pages: 339-372
Publisher: University of Kufa جامعة الكوفة

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Abstract

This research shows the spatial distribution of population fertility in Iraq as well as the reasons and direction of population fertility for 1997-2007. Fertility direction had been recognized via the statistical analysis by using the criteria degree for all fertility levels in Iraq. It deals with birth general average, fertility general average, gender- average fertility average, total growth average, fertility total average and children to women rate. Of the most important results of the research are that birth average in the studied year had increased lightly, fertility general average directed towards decrease, (25-29) age group represents the highest one for female and total growth average, fertility total average and children to women rate had decreased remarkably. So it is necessary to organize family by diffusing the awareness of contraceptive devices, encouraging women to have the required scientific level, and working in all governorates to have the same direction of fertility via the family planning and organizing

This research shows the spatial distribution of population fertility in Iraq as well as the reasons and direction of population fertility for 1997-2007. Fertility direction had been recognized via the statistical analysis by using the criteria degree for all fertility levels in Iraq. It deals with birth general average, fertility general average, gender- average fertility average, total growth average, fertility total average and children to women rate. Of the most important results of the research are that birth average in the studied year had increased lightly, fertility general average directed towards decrease, (25-29) age group represents the highest one for female and total growth average, fertility total average and children to women rate had decreased remarkably. So it is necessary to organize family by diffusing the awareness of contraceptive devices, encouraging women to have the required scientific level, and working in all governorates to have the same direction of fertility via the family planning and organizing

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