research centers


Search results: Found 7

Listing 1 - 7 of 7
Sort by

Article
4.REPRODUCTIVE HORMONAL ASSAY OF A SAMPLE OF IRAQI OBESE MALES

Authors: Imad M. Abdul-Rahman عماد محمود عبد الرحمن --- Atheer J. Abdul-Ameer اثير جواد عبد الامير
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2019 Volume: 17 Issue: 2 Pages: 114-119
Publisher: Al-Nahrain University جامعة النهرين

Loading...
Loading...
Abstract

Background:The World Health Organization considered obesity as a medical condition that may lead to reduced life expectancy and/or increased health problems. While much of the focus on the impairments caused by obesity is on somatic health, recent data suggest that reproductive health may also be impacted.Objective:To quantify the relation between obesity and the reproductive hormones.Methods:This cross-sectional study was carried out at nutrition clinic in three teaching hospitals and one obesity clinic in a medical college in Baghdad. The body mass index (BMI) calculation, blood sugar, serum cholesterol, triglyceride, testosterone, prolactin, follicular stimulating hormone (FSH), and luteinizing hormone (LH) were measured.Results:Ninety-five adult obese males participated in this study. Serum testosterone had significant negative correlation with BMI, weight, serum cholesterol, and serum triglyceride while serum LH had significant positive correlation with BMI (p value was 0.013), weight (p value was 0.027), and serum triglyceride (p value was 0.049).Conclusion:Male obesity has significant effect on serum level of testosterone and LH.Keywords:Obesity, reproductive hormonesCitation:Abdul-Rahman IM., Abdul-Ameer AJ. Reproductive hormonal assay of a sample of Iraqi obese males. Iraqi JMS. 2019; 17(2): 114-119. doi: 10.22578/IJMS.17.2.4


Article
Study The Relationship Between Some Sex Hormones and Toxoplasmosis Among Infertile Men Patients in Thi-Qar Province

Authors: Jabbar H. Fezaa --- Mohannad Abd-Al Razzaq Gati --- Bassad A. Al-Aboody
Journal: Journal of Education for Pure Science مجلة التربية للعلوم الصرفة ISSN: 20736592 Year: 2019 Volume: 9 Issue: 2 Pages: 151-157
Publisher: Thi-Qar University جامعة ذي قار

Loading...
Loading...
Abstract

Abstract:Toxoplasma gondii is the causal agent of Toxoplasmosis which infects a large proportion of the world’spopulation, but clinically uncommonly causes significant disease. The present study was performed toestimate the relationship between toxoplasmosis and some sex hormones (testosterone hormone , folliclestimulating hormone (FSH) and luteinizing hormone ) and also to estimate the prevalence of toxoplasmosisin infertility men. 280 samples of both infertile patients(180) and controls(100) had been tested by ELISAtechnique to detect anti-Toxoplasma Abs (IgG and IgM).The levels of sex hormones were also tested inmen sera by ELISA test. The results of the present study in both infertile patients and healthy controlsshowed presence of anti-Toxoplasma IgG Abs in 40 out of 180 (22.23%) and 16 out of 100 (16%)respectively. While the result of ELISA- IgM test was (0 %) in both subjects .The results of sex hormonesappeared the level of testosterone hormone was lowest in infertile patients infected with toxoplasmosiscompared to higher level of hormone in non infected infertile patients and control groups.


Article
Studying the effect of Metformin and Enzyme inhibitor drags on the level of aromatase Enzyme in the women have hormone disorder the Kirkuk city
دراسة تأثير عقارMetformin و مثبط الإنزيم على مستويات إنزيم Aromatase Enzyme في النساء المصابات باضطرابات هرمونية في مدينة كركوك.

Author: Saria Naji Muhsin ساريا ناجي محسن
Journal: Univesity of Thi-Qar Journal مجلة جامعة ذي قار العلمية ISSN: 66291818 Year: 2019 Volume: 14 Issue: 1 Pages: 62-71
Publisher: Thi-Qar University جامعة ذي قار

Loading...
Loading...
Abstract

This study included ( 100 ) samples of women used drugs Metformin, enzyme inhibitor in (Azadi General Hospital) (20) blood samples aspirated from healthy women as control sample. The samples were divided into three groups; the first group (40) women used Metformin (have primary infertilits), the second group (40) women used Letrazole (have Secondary infertilits). The third group was the healthy women(control). The results of the study indicated a significant decrease (p<0.05) in the Activity of Aromatase level in Primary infertile women age groups (18-25), (26-35) and (36-45). the results of this study reveal that three is significant decrease in the Activity of Aromatase (p<0.05) in women who have Secondary infertility with age groups (18-25), (26-35) and (36-45). This Drugs causes decreasing the level of the Estrogen by inhibiting the Aromatase Enzyme . The Drugs also called as (Enzyme inhibitor) because they inhibit Aromatase enzyme, This proves that the Letrazole Drugs has an effective role in stimulating ovulation in women who have primary and secondary infertility

شملت هذه الدراسة (100) عينة من النساء يستخدمن عقاري Metformin ومثبط الإنزيم في (مستشفى أزادي العام) في مدينة كركوك.(20) عينة دم سحبت من نساء غير مصابات كعينة ضابطة.العينات قسمت إلى ثلاثة مجاميع’المجموعة الأولى(40)من نساء يستخدمن عقار Metformin (مصابات بالعقم الأولي),المجموعة الثانية:(40)من نساء يستخدمن عقار مثبط الإنزيم(مصابات بالعقم الثانوي), والمجموعة الثالثة (20) من نساء غير مصابات كعينة( ضابطة) .لقد بينت نتائج البحث بوجود انخفاض معنوي في مستوى فعالية إنزيم الارومتيزعند مستوى(p<0.05) في مجموعة النساء المصابات بالعقم الأولي للفئات العمرية (18-25), (36-45)’ (26-35). و أظهرت نتائج البحث أيضا انخفاضاً معنوياً p <0.05) ) في مستويات فعالية إنزيم الأرومتايز في مجموعة النساء المصابات بالعقم الثانوي للفئات العمرية (18-25), (36-45)’ (26-35). هذا العقار يسبب انخفاض عالي في معدلات الاستروجين بواسطة تثبيط فعالية إنزيم الأرومتايز,وكذالك يدعى هذا العقار (Enzyme inhibitor) لأنه يثبط إنزيم الأرومتايز .وهذا يبرهن إن عقار Letrazole له دور فعال في تحفيز الاباضة في النساء المصابات بالعقم الأولي والنساء المصابات بالعقم الثانوي .


Article
The Value of Free Thyroid Hormones and Aspartate Aminotransferase in Vaginal Washing Fluid for Detection of Preterm Pre-Labor Rupture of Membrane

Author: Maha Mohamed Jasim Al-Bayati*, Eaman Marouf Muhammad**, Athmar Maamon Salman**
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2019 Volume: 18 Issue: 1 Pages: 52-58
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND:Preterm pre-labor rupture of membrane occurs in about 2% of all pregnancies. The most frequentconsequences of preterm pre-labor rupture of membrane is preterm delivery, sepsis and pulmonaryhypoplasia. The correct diagnosis of preterm pre-labor rupture of membrane is crucial and successfulmanagement will be based upon it.OBJECTIVE:To determine whether measurement of vaginal washing fluid aspartate aminotransferase(AST) ,free triiodothyronine (free T3) and thyroxin(free T4) were useful tests for the diagnosis of pretermpre-labor rupture of membrane.STUDY DESIGN: A case - control study.SETTING: :This study was conducted at department of Obstetrics and Gynecology of AL-Yarmoukteaching Hospital and National center for DiabetesPATIENTS, MATERIALS AND METHODS:It included hundred pregnant women with a gestational age ranging between 24 - 36+6 weeks. Theywere divided into two groups, the study group which included fifty pregnant women presented withpreterm pre-labor rupture of membrane and the control group which includes fifty pregnant womenwithout any complaint, matched for gestational age. All women underwent sterile speculum vaginalexamination. Free triiodothyronine and free thyroxin levels were measured by using Enzyme immuneassay method, and aspartate aminotransferase level was measured by using colorimetric method, invaginal washing fluid.RESULTS:Vaginal washing fluid free T3, free T4 and AST levels were significantly higher in the study group(1.15), (0.071), (4.9) respectively compared with the control group (0.93), (0.048), (4.5) respectively.Vaginal washing fluid free T4 having the largest area under the curve on receiver operatingcharacteristic curve (ROC) analysis (P<0.001). ROC curve analysis showed that free T3 validityresults in predicting preterm pre labor rupture of membrane among pregnant women were (cut-off1.07pg/ml, sensitivity 88%, specificity 76% and accuracy 82%), free T4 validity results were (cutoff0.055pg/ml, sensitivity 84%, specificity 80% and accuracy 82%) and AST validity resultswere (cut-off 4.9IU/L, sensitivity 52%, specificity 80% and accuracy 66%).CONCLUSION:Measurement of aspartate aminotransferase free triiodothyronine , and thyroxin in vaginal washingfluid of suspected and diagnosed patient presented with preterm pre labor rupture of membranefound to be a useful markers for the diagnosis of preterm pre labor rupture of membrane..


Article
Combination of atorvastatin and fenofibrate altered androgenic activities of male rats

Authors: Kawa F. Dizaye --- Sundus Rashad Ahmed
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2019 Volume: 23 Issue: 2 Pages: 273-282
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

Loading...
Loading...
Abstract

Background and objective: Many drugs and chemical substances may induce sexual dysfunction and have a negative impact on male fertility. Lipid-lowering agents like statins and fibrates are usually recommended for cardiovascular diseases prevention. However, the combination of atorvastatin and fenofibrate is the subject of questions concerning their effect on androgenic activities in this study. This study was designed to evaluate the efficacy and toxicity of atorvastatin, fenofibrate, and their combination on sperm parameters, sexual hormones, and histopathology of the testis. Methods: Twenty-four male rats were divided into four groups, each of six. The first group served as a control. The second, third, and fourth groups received atorvastatin, fenofibrate, and their combination, respectively. After 28 days, blood samples were collected for hormones and other parameters evaluations. Testis and epididymis were taken for histopathology studies and sperm parameters assessments.Results: Fenofibrate showed a significant reduction in sperm viability and serum levels of luteinizing and estradiol hormones. The combination of both drugs significantly reduced the sperm count and viability in normal male rats. Both atorvastatin and its combination mildly changed the histological structures of the testis, reduced number of spermatozoa, and arrested spermatogenesis.Conclusion: The findings from this prospective study suggested that there was no harmful effect of atorvastatin usage on conventional sperm parameters and sexual hormones. Fenofibrate usage was not adversely associated with sperm parameters other than sperm viability. The combination of atorvastatin and fenofibrate significantly reduced the sperm count and viability. No deleterious effects of the drugs were seen on the testosterone, which was the essential hormone for all stages of spermatogenesis, sperm production, maturation, and transport.


Article
Effect of Body Mass Index on Abnormal Ovarian Secretion Hormones among Iraqi Women with Polycystic Ovarian Syndrome (PCOS)

Authors: Alaa H. Badr --- Alaa H. Jawad --- Rania M. L. Faraj
Journal: Al-Nahrain Journal of Science مجلة النهرين للعلوم ISSN: (print)26635453,(online)26635461 Year: 2019 Volume: 22 Issue: 1 Pages: 40-45
Publisher: Al-Nahrain University جامعة النهرين

Loading...
Loading...
Abstract

Polycystic ovarian syndrome (PCOS) is the most common and complex endocrine disorder affecting women in the reproductive age. The etiology of this syndrome is not completely known, so there is a developing proof that supports genetic basis, PCOS has a strong familial preference. This study was carried out to investigate the effect of body mass index (BMI) on ovarian hormones in women with PCOS and healthy women. Eighty-three women aged (17-40) years were divided into two groups for testing (BMI less than 25 and more than 25). Hormonal study of Luteinizing hormone (LH), Androgen, Estradiol (E2) was done for each patient, the results of these hormones in patients compared with controls in both BMI groups with E2/T ratio showed a significant increase in patients women compared to controls in (p<0.05), While the results of Follicle stimulating hormone (FSH) and Total Testosterone (TT) showed an increase with not statistically significant. it has been concluded that the increase in BMI doesn’t show to have an opposite effect on FSH, Androgen, E2, and TT levels but the result of LH shows a highly significant increase in PCOS groups compared to controls when BMI˃25.

Keywords

Polycystic ovarian syndrome --- LH --- E2 --- FSH --- TT --- BMI --- ovarian hormones --- Androgen.


Article
EVALUATION OF MEDICINAL PLANTS (ASTRAGALUS ERIOCEPHALUS AND QUERCUS INFECTORIA) AS FEED ADDITIVES IN AWASSI EWES’ RATION
تقيم النباتات الطبية (Quercus infectoria and Astragalus eriocephalus) كاضافة علفية في عليقة النعاج العواسية 2-بعض صفات الكيمياوية للدم ومستوى الهورمات وصحة الحليب

Author: M. S. Q. Barwary
Journal: Iraqi Journal of Agricultural Science مجلة العلوم الزراعية العراقية ISSN: 00750530/24100862 Year: 2019 Volume: 50 Issue: 2 Pages: 526-533
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

The aim of this study was to investigate the effect of addition two medical plants or their mixture on hematological, biochemical parameters, hormonal levels and milk microbiology of lactating Awassi ewes. Twenty-eight ewes at mid lactation were divided into four groups and fed rations containing 1% Gall oak, 2% Astragalus, 0.5 Gall oak + 1% Astragalus, and Control. At biweekly intervals, blood samples were withdrawn. A bulk milk samples was collected for microbiological test under sterilized conditions. Results revealed that medicinal plants significantly influenced Erythrocyte Sedimentation Rate being lowest in the Astragalus group. Ewes feed Mixture group had significantly higher blood glucose concentration. Cholesterol level was significantly lower in the blood of ewes fed Gall oak diet and was highest in ewes fed Astragalus diet. Animals fed diet supplemented with Gall oak had a significantly higher concentration of T3 hormone. Total viable bacterial and mold count was decreased in the milk of Astragalus and Gall oak group, respectively. It can be concluded that Astragalus eriocephalus and Quercus infectoria improved immunity, metabolism and milk hygiene of lactating Awassi ewes.

هدف الدراسة,استعمال النباتات (العفص والكثيراء) بشكل فردي اوخليط منهما كاضافة في عليقة نعاج العواسية الحلوبة للكشف عن تاثيرها في الصفات الدموية ومستوى الهورمونات (T3, T4, برولاكتين, كورتيزول) واحتواء الحليب على الاحياء المجهرية. تم استعمال ثمانية وعشرون نعجة حلوبة في منتصف مرحلة ادرار الحليب وقسمت الى اربع مجاميع حيث غذيت نعاج المجاميع الاربعة على علائق حاوية على 1% العفص, 2% الكثيراء, 0.5 العفص+1% الكثيراء ومجموعة المقارنة. تم سحب الدم كل اسبوعين مرة. وجمع عينات الحليب من كل مجموعة لدراسة الاحياء المجهرية في الحليب. كانت للنباتات المضافة تاثيراً معنيويا في معدل ترسيب كريات الدم الحمراء اذ كانت ادناها في المجموعة المغذاة على الكثيراء. كان مستوى الكلوكوز اعلى معنوياً في المجموعة المغذاة على خليط النباتين. كان مستوى الكوليسترول ادنى معنويا في دم النعاج المغذاة على عليقة العفص واعلاه في دم النعاج المغذاة على نبات الكثيراء. كما كان مستوى هورمون T3 اعلى معنوياً في مجموعة النعاج المغذاة على عليقة العفص. انخفض العدد الكلي للبكتيريا والفطريات في حليب النعاج المعاملة. يمكن الاستنتاج بان اضافة النبات العفص والكثيراء يعمل على تحسن المناعة و الايض وصحة الحليب في النعاج العواسية الحلوبة.

Listing 1 - 7 of 7
Sort by
Narrow your search

Resource type

article (7)


Language

English (7)


Year
From To Submit

2019 (7)