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Article
Estimation of Aromatase Enzyme in Obese Infertile Men

Authors: Ula M. AL-Kawaz --- Nawal K. AL-Ani --- Hikmat F. Wassef
Journal: Iraqi Journal of Embryos and Infertility Researches المجلة العراقية لبحوث الأجنة والعقم ISSN: eISSN: 26166984 / pISSN: 22180265 Year: 2016 Volume: 6 Issue: 1 Pages: 22-31
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background: Male obesity is associated with physiological changes that can negatively affect male fertility. Obese men have demonstrated a 3-fold increase in the prevalence of oligozoospermia when compared with men with normal Body Mass Index (BMI). Objective: To estimate the role of aromatase enzyme in decreasing sperm parameters in obese infertile men. Subjects, Materials and Methods: Seventy obese infertile male (patients) and twenty obese fertile male (control) are enrolled in this study. Seminal fluid analysis done according to criteria of WHO (2010). Results: A significant negative correlation was found between human cytochrome enzyme and sperm concentration, progressively motile sperm, non-progressively motile sperm, immotile sperm and normal morphology.Conclusion:The present study showed clearly that male obesity negatively impacts fertilitythrough direct association between increased (BMI) and semen parameters. Theresults suggest that increased estrogen as a result of aromatization in the fattytissue, reflected through the increase in human cytochrome enzyme (aromatase),may be an important mechanism for the hypoandrogenemia and altered spermparameters


Article
Estimation of Aromatase Enzyme in Obese Infertile Men in Correlation with Sex Hormones and BMI

Authors: Hikmat F. Wassef --- Nawal K. AL-Ani --- Ula M. AL-Kawaz
Journal: Iraqi Journal of Embryos and Infertility Researches المجلة العراقية لبحوث الأجنة والعقم ISSN: eISSN: 26166984 / pISSN: 22180265 Year: 2017 Volume: 7 Issue: 1 Pages: 62-70
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Male obesity is associated with physiological changes that can negatively affect male fertility. Obese men have demonstrated a 3-fold increase in the prevalence of oligozoospermia when compared with men with normal Body Mass Index (BMI).

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