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Epidemiological, Clinical, and immunological characteristics of Mycoplasma pneumonia infections among a group of hospitalized children in Suleimani city/Iraq .

Author: Ali H. bayati*, Pakhshan M. Faraj*, Khalid H. Salih**
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2014 Volume: 10 Issue: 2 Pages: 5-9
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Mycoplasma pneumoniae (M. pneumoniae) is an important respiratory bacterial pathogen, especially among children. It causes acute upper and lower respiratory infections.Objective: This study was aimed to measure anti- M. pneumoniae antibodies among hospitalized children who were admitted to hospital diagnosed with acute respiratory tract infections.Method: Automated ELISA technique was performed to detect anti- M. pneumoniae antibodies (IgM and IgG antibodies) in serum from 108 children less than 5 years old. The children were admitted to the Pediatric Teaching Hospital in Suleimani city/Kurdistan Region/Iraq because of acute respiratory tract infections. A questionnaire was designed to collect demographic and clinical data from those children.Results: IgM anti- M. pneumoniae antibodies were positive in 15 (13.9%) out of 108 children. The highest seroprevalence was found in the age group 25-36 months while the lowest is in the age group 1-12 months. M. pneumoniae infections were more common among males than females though results were statistically not significant, and attendance of kindergarten or nursery, residency, history of chronic diseases, history of contact with similar conditions, and family history of chronic diseases, they were all statistically not significant. The IgMseropositive children were suffering from bronchitis, croup, pneumonia, or other respiratory infections, in frequencies of 7 (46.6%), 4 (26.7%), 3 (20%), and 1 (6.7%) respectively. Increased erythrocyte sedimentation rate, diagnosis of croup, and diagnosis of bronchitis were more frequent in M. pneumoniae infected group and the results were statistically significant. The IgG anti- M. pneumoniae antibodies were positive in 31 (28.8%) out of the 108 children, and the greatest IgG seroprevalence was highest in age group 49-60 months.Conclusion: M. pneumoniae is an important respiratorypathogen among hospitalized children in Sulaimanigovernorate/Kurdistan/Iraq, and nearly one third of childrenhad experienced M. pneumoniae infection by the age of fiveyears


Article
Risk of birth defects and other childhood adverse outcome associated with in vitro fertilization

Authors: Adnan M. Hamawandi --- Khalid H. Salih --- Hind N. Ayoub --- Amanj R. Zangana
Journal: Iraqi Journal of Embryos and Infertility Researches المجلة العراقية لبحوث الأجنة والعقم ISSN: eISSN: 26166984 / pISSN: 22180265 Year: 2014 Volume: 4 Issue: 2 Pages: 40-46
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background:In vitro Fertilization (IVF) is an important alternative for infertile couples, there is anincrease in the number of children conceived by IVF worldwide.Objective:The aim of this study was to assess the risk of birth defects and adverse outcome amonginfants and children conceived by in vitro fertilization in Sulaimani-Iraq.Patients and Methods:This case-control study was carried out on 160 children, 75 were product ofIVF(using ICSI) and 85 were product of natural conception. Data collectedregarding mother age, father age, duration of infertility before pregnancy with theindex child, any complication during pregnancy, age of the child, gender, mode ofdelivery, gestational age, weight at delivery, history of neonatal admission andit’s cause, admission to hospital after neonatal period, and history of surgicaloperation. All children were examined for any gross anomaly, cardiovascular,respiratory, gastrointestinal, skeletal, urological and neurologic abnormality.Results: IVF was a risk factor for prematurity (OR, 7.844 95% CI 3.025 - 20.339) ,LBW (OR, 4.645 95% CI 2.038 -10.587), Congenital anomaly (OR, 1.362 95% CI 0.720 -2.576), predominance of male gender (OR, 1.340 95% CI 0.719-2.498), neurodevelopmentaldelay(OR,1.333 95% CI 0.672- 2.646), admission to NICU (OR,1.703 95%CI 1.052-2.758 ), C/S delivery (OR, 1.972 95% CI 1.507-2.581), and childhoodhospitalization (OR, 1.193 95% CI 0.838-1.696), also there was statistically significantassociation with multiple pregnancy.Conclusions:IVF carries increased risk of LBW, prematurity, congenital anomaly, neuro-developmentaldelay, admission to NICU, childhood hospitalization, C/S as a mode of delivery andpredominance of male gender.

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