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Article
Antiviral Effect of Ethanolic Extract of Salvadora Persica (Siwak) on Herpes Simplex Virus Infection.

Author: Mahmoud YM Taha
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2008 Volume: 8 Issue: 1 Pages: 50-55
Publisher: Mosul University جامعة الموصل

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Abstract

Aims: To investigate the effect of ethanolic extract of Salvadora Persica extract on HSV–1 infection
both in vitro and in vivo in the mouse model system. Materials and methods: Ethanolic extract of
Salvadora Persica was used at different concentrations. BHK cells that grown in Eagles medium were
used for virus isolation and titration using PFU/ml. The effects of different concentrations of Salvadora
Persica on viral growth in BHK cells as well as cytolytic activity of HSV–1 were evaluated at different
time post infection. The therapeutic efficacy of Salvadora Persica in vivo was studied in mice. Lesions
were scored and viral isolation from infected skin and ganglia was titrated on BHK cells. Results:
Salvadora Persica inhibited the replication of HSV–1 in BHK cells as well as the cytolytic activity of
cell free virus. Topical application of Salvadora Persica on the skin of mice infected with HSV–1
reduced the development of cutaneous lesions and the viral titers in the skin and ganglia were also
reduced. Conclusion: The results of this work may be beneficial for the treatment of recurrent oral
herpes infections.

Keywords

Miswak --- Antiviral --- HSV–1


Article
A Clinical Association of Dry Socket and Postoperative Pain with Typhoid fever as Risk Factor

Authors: Mahmoud YM Taha --- Faraed D Salman
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2011 Volume: 11 Issue: 1 Pages: 71-77
Publisher: Mosul University جامعة الموصل

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Abstract

Aims: To identify the clinical picture and the association between dry socket and severe postoperative development with one of the systemic risk factors (typhoid fever). Materials and Methods: Twenty adult (both sexes) patients attended dental clinic searching for different dental treatments were studied. The clinical picture of 6 months period study was evaluated by completing two case sheet forms. They were diagnosed having dry sockets and severe postoperative pain. Blood samples were taken for bacte-riological, serological and hematological study to diagnose typhoid fever. These tests included WAT, WFT, WBCs and blood culture. Results: Significant correlation existed between postoperative pain and typhoid fever examined by BC and the highest percentage was with dry socket (61.5%) followed by WFT (57.1%(, WAT (44.4%) using two tests for diagnosis showed that WFT and BC gave 97.9% positive for dry socket and Kappa test was 88%, while WAT and WBCs or WFT and WAT gave the least non significant correlation. Conclusion: There was a strong correlation between dry socket and typhoid fever and the most sensitive tests for diagnosis was BC followed by WFT, WBCs and WAT.


Article
Assessment of transient bacteremia following various oral and dental interventions

Authors: Mohammad Kh Hasouni --- Wael T Al–Wattar --- Mahmoud YM Taha
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2003 Volume: 3 Issue: 1 Pages: 50-56
Publisher: Mosul University جامعة الموصل

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Abstract

The incidence of bacteremia following various dental interventions of 280 selected patients were studied using blood culture technique with aerobic and anaerobic cultivation. The incidence of bacteremia after multiple teeth extraction was higher (51.72%) than those single tooth extraction (44%). The incidence of bacteremia after local anaesthetic injection differs according to the type of injections significantly. In scaling and root planning the use of local prophylactic solution reduced the incidence of bacteremia from 37.7% to 13.9%. Poor oral hygiene had an effect on incidence of bacteremia at different dental interventions. The role of sex and age in bacteremia was variable. Aerobic bacteria were more than anaerobic and the most common bacteria isolated were Streptococcus viridans (30.5%) and Staphylococcus aureus (19.7%).

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