research centers


Search results: Found 4

Listing 1 - 4 of 4
Sort by

Article
Epidemiological, Clinical Profiles and Outcome of Bronchiolitis in Iraqi Children

Author: Muhi K. Al-Janabi محي كاظم الجنابي
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2007 Volume: 49 Issue: 4 Pages: 407-413
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Bronchiolitis is the first episode of wheezing associated with low-grade fever, rhinitis, tachypnea, and increase respiratory effort in a previously healthy infant during the winter months. It is the most common disease of the lower respiratory tract. Methods: This is a case control study carried out on one hundred infants with a mean age of 3.9 months ± 2.2 months admitted to Children Welfare Teaching Hospital in Medical City – Baghdad with acute bronchiolitis during the period from 1st January 2006 to 1st April 2006. epidemiological risk factors, clinical presentations, chest X-ray findings, treatment, complications and outcome were analyzed. Another one hundred infants (age and sex matched) were seen in the outpatient clinical in the same period and for health problems other than bronchiolitis were taken as a control group. Chi square test was used and a P<0.05 was considered significant. Results: It was found that 64% of patients were males and 36% were females M/F: 1.9/1, 80% were <6 months and 20% were >6 months of age. Most cases (87%) were admitted on January and February. Bronchiolitis was uncommon and less severe in neonatal period. There was a significant association between urban residence and acute bronchiolitis. There was no significant association between each of family history of atopy, parental smoking, pets at home and crowding index > 30 with bronchiolitis. Fever >38.1C was significantly more common in infants with bronchiolitis > 6 months of age than those less than 6 months. Conclusions: The mean clinical scores of severity, the mean duration of hospitalization and Chest X-ray findings were higher in: male sex, age <6 months, infants who were on exclusive breast feeding. Corticosteroids did not reduce the duration of hospitalization in children with acute bronchiolitis.

Keywords


Article
Validation of Kala-azar diagnostic tests in a pediatric teaching hospital in Baghdad
صحة الاختبارات التشخيصية للحمى السوداء في مستشفى تعليمي للأطفال في بغداد

Authors: Muhi K. Al-Janabi محي كاظم --- Nadia A. Nasir نادية عزيز --- Ammar A. Hameed عمار عبد الحميد
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2014 Volume: 56 Issue: 3 Pages: 264-267
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Kala-azar is an important parasitic disease that affects children of all age groups with fatal outcome if left without treatment.Objectives: Children admitted with Kala-azar were studied for evaluation of Indirect Immunoflorescent Antibody Test and Bone Marrow examination validity.Patients and methods: A cross-sectional study was conducted on 60 children with Kala-azar admitted to Children Welfare Teaching Hospital - Medical City - Baghdad, for the period from the 1st of January 2011 to the 1st of February 2012. Information was obtained for each child including age, sex, residence, signs and symptoms, laboratory investigations and diagnosis was established by serology and/or bone marrow examination. Treatment and outcome were also noted.Results: The majority (94%) of studied children were less than 5 years age group. Males were more than females with a ratio of 1.63:1. Sixty percent of patients were from Diyala governorate and 23% from Baghdad. The main clinical features were prolonged fever and hepatosplenomegaly (100%). Bone marrow examination was positive in 45% of suspected Kala-azar cases. IFAT was positive in 47(78%). IFAT sensitivity was 70% and specificity 15%. All cases were treated with Pentostam (sodium stibogluconate). No resistance to Pentostam treatment was detected. The case mortality rate was 2%.Conclusion: The highest sensitivity in laboratory diagnosis among studied children was that obtained with a combination of bone marrow aspirate direct examination and IFAT. Conventional methods for diagnosis of visceralLeishmaniasis are still indispensable.Keywords: Validity, kala-azar, diagnosis, Baghdad

الخلفية: الحمى السوداء هو مرض طفيلي مهم يصيب الأطفال من جميع الفئات العمرية مع نتائج قاتلة إذا تركت دون علاج.الاهداف: IFAT تمت دراسة الأطفال الذين أدخلوا المستشفى مصابين بالحمى السوداء لتقييم صلاحية اختبار المرضى والطرق: أجريت دراسة مقطعية على 60 طفلا مصابين بالحمى السوداء الذين ادخلوا في مستشفى حماية الأطفال التعليمي في بغداد، للفترة من 1 يناير 2011 إلى 1 فبراير 2012. تم الحصول على معلومات عن كل طفل بما في ذلك السن والجنس والإقامة، والعلامات والأعراض، والفحوصات المختبرية وتأسس التشخيص عن طريق الأمصال و / أو الفحص نخاع العظام. وتم تثبيت العلاج والنتيجة النهائية. النتائج: كانت الغالبية (94٪) من الأطفال المشمولين بالدراسة أقل من 5 سنوات من العمر. ويصيب المرض الذكور أكثر من الإناث بنسبة 1.63:1. كان 60٪ من المرضى من محافظة ديالى وكان 23٪ من بغداد. كانت المظاهر السريرية الرئيسية حمى لفترة طويلة وتضخم الكبد و الطحال (100٪). وكانت النتائج إيجابية لنخاع العظام عند السوداء. 45٪ من الحالات المشتبه الحمى هي 70٪ وخصوصيته 15٪.IFAT كانت حساسية فحص تم علاج جميع الحالات بعقار البنتتوستام ، لم يتم الكشف عن أي مقاومة للبنتتوستام. كان معدل الوفيات 2٪.الاستنتاج: أعلى حساسية في التشخيص المختبري عند الأطفال المصابين بالحمى السوداء عن طريق فحص نخاع ومازالت طرق التشخيص التقليدية من الحمى السوداء ضرورية في مكان الدراسة مباشرة مع فحص. IFAT مفتاح الكلمات: صحة,الحمى السوداء,التشخيص, بغداد


Article
B- THALASSEMIA MAJOR IN RAMADI

Loading...
Loading...
Abstract

Summary:Background:The thalassemias are a heterogeneous group of genetic disorders in which the production of normal hemoglobin is partly or completely suppressed because of a defective synthesis of one or more globin chain Jn Iraq, B - thalassemia major is widely distributed all over the country.An active program for the hereditary blood diseases had been adopted in cooperation with WHO in 1989. This study is done to evaluate the burden of the disease and its treatment on thalassemic patients in Ramadi.Methods: Thirty-one children with B- thalassemia major (17 males and 14 females) aged 9 months- 21 years attending the thalassemic clinic in MCH in Ramadi during the period from Is' Dec. 2001 to 31s' May 2002 were studied prospectively. _History, clinical examination , investigations, treatment and its complications were noted and analysed. Statistical analysis was done by the use of SD, t-test and P value of <0.05was considered statistically significant.Results: 90% had pretransfusion Hb <9gm/ dl. Only 27%> received Desferal regularly subcutaneously by infusion pumps. Splenectomy was done in 19.3%, all of them received pneumococcal vaccine and half of them received Benzathine penicillin regularly monthly. Body weight and height below 3rd percentile were noticed in 22.5% and 32.2% respectively. About 32% had myocardial systolic or diastolic dysfunction detected by Doppler echocardiography. Non had hypocalcemia. HBs Ag positive in 6.4%. Anti HCV was positive in 12.5%.None was positive for HIV.Conclusions:_The majority of patients were undertreated and various complications were probably related to chronic anemia rather than iron overload. Keywords: thalassemic

Keywords

thalassemic


Article
H1N1 Influenza epidemic in children in Baghdad… a hospital based study
الكشف عن فايروس الأنفلونزا H1N1عند الأطفال في مستشفى تعليمي أثناء الوباء في بغداد

Loading...
Loading...
Abstract

Background: A confirmed case of influenza A (H1N1) virus infection is defined as a person with an influenza-like illness with laboratory confirmed influenza A (H1N1) virus infection by real-time RT-PCR or viral culture.Objectives: To identify demographic and clinical predictors, and outcome of proved cases of H1N1 influenza epidemic in children.Patients and methods: This study was conducted in Children Welfare Teaching Hospital/ Medical City/ Baghdad on 67 hospitalized patients aged 1 month to 18 years with signs and symptoms suggestive of influenza during the period of outbreak of pandemic influenza A (H1N1) from 1st of October 2009 to 1st of January 2010. Demographic aspect, clinical coarse, laboratory investigations, treatment and outcome were reported. For each patient 2 nasal, 2 throat swabs and single blood sample were collected, and sent to Central Health Laboratory. All suspected patients received Oseltamivir for 5 days. The data were analyzed statistically by Chi-square (χ2) test and Fisher's Exact Test.Results: The median age for the studied patients was 7.7 years with a range of 1 month -18 years. 39 patients out of 67 (58.2%) were PCR positive. 34 out of 39 (87.1%) were <6-18 year old while 5 out of 39 (12.9%) were >3-6 years old. No case was reported in age group 1 month-3 years. Twenty eight patients out of 67 (41.8%) were PCR negative. 17/28 (60.7%) were <6-18 years old. 5 out of 28 (17.9%) were >3-6 years old. 6 out of 28 (21.4%) were 1 month -3 years old. Female: male ratio in PCR positive patients was 1.05:1 while it was 1.54:1 in PCR negative patients. Most of the children came from urban area in both PCR positive and negative results. Cough and fever had a higher frequency in both PCR positive and negative patients while headache was more in epidemic influenza. All PCR positive and 26 out of 28 (92.8%) of PCR negative patients improved while 2 out of 28 (7.2%) of PCR negative patients died.Conclusions: Children at school age were more prone to acquire epidemic influenza. Both genders were equally affected. Frequency was more in urban area .Cough and fever was the most frequent presentation. Headache was a more common presentation in H1N1 influenza than in seasonal influenza.Key words: Influenza, Epidemic, Children, Baghdad

الخلفية :تعتبر الحالة المؤكدة من عدوى فايروس ( H1N1 ) لشخص يعاني من أعراض تشبه الإنفلونزا ويؤكد الفحص المختبري وجود فايروس ( H1N1 ) عن طريق فحص تفاعل البلمرة المتسلسل - الوقت الحقيقي RT- PCR أو زرع الفيروس . أهداف الدراسة : لتحديد الخواص الديموغرافية والوبائية والسريرية لإنفلونزا H1N1 في الأطفال الذين أدخلوا المستشفى يعانون من اعراض الانفلونزااثناء فترة الوباء.المرضى و الطرق : أجريت هذه الدراسة في مستشفى حماية الاطفال التعليمي – مدينة الطب - بغداد على 67 مريضا تتراوح أعمارهم بين شهرواحد و 18 سنة مع وجود علامات وأعراض الأنفلونزا أثناء فترة انتشار أنفلونزا الجائحة ( H1N1 ) من 1 من أكتوبر 2009 إلى 1 يناير 2010 . سجل الجانب الديموغرافي ، والحالة السريرية، و الفحوص المختبرية والعلاج و النتيجة النهائية . تم اخذ مسحتان للحلق وعينة دم واحدة لكل مريض ، وأرسلت إلى مختبر الصحة المركزي . تلقى جميع المرضى المشتبه باصابتهم بالأنفلونزا الجائحة عقار أوسيلتاميفير لمدة 5 أيام . وقد تم تحليل البيانات إحصائيا بواسطة اختبار مربع كاي و اختبار فيشر.النتائج: كان متوسط العمر للمرضى 7.7 سنة ويتراوح بين1 شهر -18 سنة. 39 مريضا من أصل 67 (58.2٪) كانت نتيجة فحص PCR إيجابية. كانت اعمار 34 من 39 (87.1٪) 6- 18 سنة, بينما 5 من أصل 39 (12.9٪) كانت 3-6 سنوات من العمر. لم يبلغ عن أي حالة في الفئة العمرية 1 أشهر 3 سنوات. وكان لدى ثمانية وعشرون مريضا من أصل 67 (41.8٪) نتيجة فحص PCR سلبية. وكانت اعمار17/28 (60.7٪) من 6-18 سنة. 5 من أصل 28 (17.9٪) كانت اعمارهم 3-6 سنوات من العمر. وكانت 6 من أصل 28 (21.4٪) 1 أشهر -3 سنة. نسبة الإناث: الذكور كانت في المرضى PCR إيجابية 1.05: 1بينما كانت 1.54:1 في المرضى PCR سلبية. وجاءت معظم الحالات من منطقة حضرية في كل من نتائج PCR إيجابية وأخرى سلبية. كان للسعال والحمى تردد أعلى في كل من PCR المرضى الإيجابية والسلبية في حين كان الصداع أكثر في الأنفلونزا الوبائية. تحسنت جميع الحالات PCR إيجابية و26 من أصل 28 (92.8٪) من المرضى PCR سلبي بينما 2 من 28 (7.2٪) من المرضى PCR سلبي توفي.الاستنتاجات: تأثر كلا الجنسين على حد سواء. وكان تردد أكثر في المناطق الحضرية. كانت الاعراض الأكثر شيوعا هي السعال والحمى. كان الصداع عرضا شائعا في انفلونزا H1N1 مما كانت عليه في الأنفلونزا الموسمية . مفتاح الكلمات: الأنفلونزا, الوبائية, الأطفال , بغداد

Listing 1 - 4 of 4
Sort by
Narrow your search

Resource type

article (4)


Language

English (4)


Year
From To Submit

2014 (2)

2007 (1)

2005 (1)