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Article
The Impact of Obesity on Some Reproductive Hormones in Infertile Men

Authors: Mahdi Abdulwahed Mahdi --- Ruwaidah Fawziy Khaleel --- Mutaz Sabah Ahmeid
Journal: Iraqi Journal of Embryos and Infertility Researches المجلة العراقية لبحوث الأجنة والعقم ISSN: eISSN: 26166984 / pISSN: 22180265 Year: 2017 Volume: 7 Issue: 1 Pages: 44-51
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Obesity, defined by the World Health Organization (WHO) as “abnormal or excessive fat accumulation that may impair health .The effects of obesity on male reproduction have been less well studied than those on female reproduction, but there is a growing body of evidence suggesting that obesity has an adverse effect on male reproduction However, a little is known about the effect of obesity on male reproductive system and infertility. Infertility is defined as inability to achieve conception within one year. It has not yet been clearly established how excess adiposity relates to the biological changes that underlie male infertility, although there are several theories worth exploring. The endocrine abnormalities associated with obesity in women are well known with an increase in androgen metabolism and changing in reproductive hormones in over weight and obese men.


Article
Malondialdehyde Level in the Patients Subjected to Open Heart Surgery in Association with Lipid Profile

Authors: Muntaha Abdulmaged Arif --- Mutaz Sabah Ahmeid --- Salih A. Allaw
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2019 Volume: 18 Issue: 1 Pages: 30-35
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Background: Reactive oxygen species are usually produced by the living cell and have different functions in its normal activity and considered as one of the factors that involved in heart disease. Malondialdehyde (MDA) considered as one of the most indictors of oxidative stress and damage produced as a result of lipid peroxidation. Objectives: The main objective is to evaluate serum oxidative stress by measuring the changes in the level of MDA as a marker of oxidative stress and demonstrate the correlation of MDA with lipid profile in patients subjected to open‑heart surgery. Methods: A case–control study was carried out in the Department of Chemistry and Biochemistry, College of medicine,Tikrit University, Tikrit, Iraq. The study was carried out for 50 patients subjected to open‑heart surgery recruited from the Medical City/IraqiCenter for Heart Disease and Ibn Al‑Bitar Cardiac Surgery Center, Department of Cardiac Surgery, Baghdad, Iraq between October 1, 2017and March 1, 2018. The levels of MDA and lipid profile were measured in the serum of 50 patients, in three different interval preoperative, early postoperative, and late postoperative and compared with 30 age‑ and gender‑matched controls. Results: The results revealed a statistically significant difference in the serum MDA level between patient during preoperative, early postoperative, and late postoperative stage against control group and significant differences in their MDA levels among all patients’ stages. Furthermore, there was a significant positive correlation between serum MDA level and total cholesterol in the early postoperative stage. Conclusions: There was an increase in the level of MDA in the early postoperative stage as an indicator of reperfusion damage that occurs immediately after open‑heart surgery which then decreases dramatically with decrease in total cholesterol, triglyceride, low‑density lipoprotein‑cholesterol (LDL‑C), and very‑LDL‑C.

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