research centers


Search results: Found 2

Listing 1 - 2 of 2
Sort by

Article
EFFECTS OF DEXAMETHASONE, ESTROGEN ADMINISTRATION ON LEPTIN, THYROID, REPRODUCTIVE HORMONE CONCENTRATION AND LIPID PROFILE OF FEMALE RABBITS SERUM.
تاثير اعطاء كل من الديكساميثازون وھرمون الاستروجين في تركيز كل من ھرمون اللبيتين وھرمونات الغدة الدرقية والتناسلية ومستوى دھون الدم في مصل دم اناث الارانب

Author: Rashad F.Ghadhban Ala AL-Deen H. Jawad رشاد فاضل غضبان علاء الدين حسن جواد
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2013 Volume: 12 Issue: 1 Pages: 41-53
Publisher: Basrah University جامعة البصرة

Loading...
Loading...
Abstract

The aim of this study investigate the effects of long term administration ofDexamethasone (DEX.) 17 β-estradiol (EST.) on body weight, concentration of somehormones ( Leptin, thyroid and reproductive hormone) in addition to determination oflipid profile of female rabbits blood serum.Thirty local rabbits were subdivided randomly and equally into three groups. Thefirst group was used as a control which injected with normal saline . The second groupwas injected daily (0.5mg /kg B.W) DEX . Intramuscularly. The third group was injectedsubcutaneously daily with 0.3 mg /kg B.W s/c 17 β-estradiol. All groups in this studywere treated for 60 days , and blood collected every 15 days. Serum was tested for leptin,LH, FSH, T3, T4 hormones total Cholesterol(TC), HDL(height density lipo-protein),LDL (low density lipo- protein),TG (triglycerides), Body weight was taken every 15 daysfrom the first day .The result showed significant (P≤0.05) decreased in body weight afteradministration of both dexamethasone (DEX.) and Estrogen (EST.), significant increasedin leptin concentration with dexamethasone (DEX.) Treatment while significantdecreased with Estrogen (EST.) treatment, in the other hand LH and FSH concentrationshowed significant decreased in both treatment dexamethasone (DEX.) and Estrogen(EST.) thyroid hormone show significant decreased with dexamethasone (DEX.)Treatment and significant increased T3 & T4 hormone with Estrogen (EST.) treatment ascompare with control while the increase in the T4 it was occurred only in the periods (45and 60)days within treatment groups , lipid profile (TC,TG,LDL, HDL,VLDL) showsignificant increased with DEX. treatment while Significant decreased with EST.treatment


Article
LEPTIN EFFECTS ON , THYROID HORMONES AND SOME BIOCHEMICAL PARAMETERS OF FEMALE RABBITS (LEPUS CUNICULUS) SERUM.
تاثير اعطاء هرمون اللبيتين على مستوى هرمونات الغدة الدرقية وبعض المعايير الكيميوحيوية لمصل دم اناث الارانب

Author: Rashad F.Ghadhban Ala AL-Deen H. Jawad رشاد فاضل غضبان علاء الدين حسن جواد
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2013 Volume: 12 Issue: 1 Pages: 178-189
Publisher: Basrah University جامعة البصرة

Loading...
Loading...
Abstract

Thirty local female rabbits were divided randomly and equally into three groups. The 1stgroup used as control which injected with phosphate buffer salin. The 2nd group was injecteddaily with leptin (5μg/animal) S/c. The 3rd group was injected subcutaneously daily with(10μg/animal) S/c. All groups were treated for 60 days, and blood samples were collected every15 days, serum was tested for T3, T4 hormones, total Cholesterol (TC), HDL (height densitylipo-protein) , LDL (low density lipo- protein), TG (triglycerides) and Body weight was takenevery 15 days during the experiment .The result show significant (P≤0.05) decreased in body weight after administration ofleptin in two doses. Significant increased in Thyroid hormone after leptin administration. Whilelipid profile (TC, TG, LDL, HDL,VLDL) show significant decreased with leptin treatment(5 and10μg/animal) S/c.

Keywords

rabbits --- T4 hormones --- Cholesterol

Listing 1 - 2 of 2
Sort by
Narrow your search

Resource type

article (2)


Language

English (1)


Year
From To Submit

2013 (2)