research centers


Search results: Found 8

Listing 1 - 8 of 8
Sort by

Article
Antibiotics Susceptibility pattern of Pseudomonas aeruginosa that isolated from ear, wound and urine samples

Authors: Adnan kreem Al-salamy --- Emad Sadiq Ali Al-Hilli
Journal: journal of the college of basic education مجلة كلية التربية الاساسية ISSN: 18157467(print) 27068536(online) Year: 2012 Volume: 18 Issue: 76 Pages: 101-112
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

A total of 181 isolates of Pseudomonas aeruginosa were obtained from 781 clinical samples from Al-Sader Medical city. The isolates were collected from ear swab(85 isolates), wound swab (70 isolates) and urine sample (26 isolates). P. aeruginosa was isolated from ear swab in high percentage 85 (46.96%) as compared with wound swab 70 (38.67%) and urine sample 26 (14.99%). The isolates of P. aeruginosa were subjected to antibiotic sensitivity test. Among various antibiotics tested, the strains showed highest resistance to ampicillin (100%), followed by Cephalothin (92.82%), Cefotaxem (84.53), Gentamycin( 69.61) and Trimethoprim (67.99), Carbencillin (67.95), Ceftriaxon (24.86), Ciprofloxacin (20.99), Cefamandol (19.33), Tobramycin(14.91), Amikacin( 14.3), and Piperacillin (12.7). Among most effective antibiotics against P.aerugionsa, with low resistant rate are Tobramycin (14.91), Amikacin (14.3), and Piperacillin (12.7) respectively. Out of 50 P.aerugionsa isolates ( retested for ESBL production)13 (26%) were found to be ESBL producers and non-ESBL were 37 (74% ). Extended spectrum beta-lactamases enzymes (ESBL) was performed by double disc diffusion method .

تم جمع 181عزله لبكتريا P.aeruginosa من مجموع العينات ألسريريه البالغ عددها 781 من مدينه الصدر الطبية، وقد جمعت هذه العينات مِن مسحات الإذن (85عزله)، مسحات الجروح (70عزله) ومن عينات الإدرار(26عزله ). لقد سجلت أعلى نسبه عزل لبكتريا P.aeruginosa في العينات التي تم أخذها من مسحات الاذن85(%46.96) مقارنه بنسبه عزلها من مسحات الجروح 70 (%38.67) و عينات الادرار26(%14.99) .كما تم اختبار حساسية بكتريا P.aeruginosa لأنواع مختلف من مضادات الحياة وقد سجل المضاد Ampicillin أعلى نسبه مقاومه(%100) يليه المضادات Cephalothin (92.82%)، Cefotaxem (84.53% )، Gentamycin ( 69.61% )، Trimethoprim ( 67.99%)، Carbencillin ( 67.95% )، Ceftriaxon ( 24.86% )، Ciprofloxacin (20.99 % )، Cefamandol ( 19.33% )، Tobramycin ( 14.91 % )، Amikacin (14.3% ) ، Piperacillin (12.7%) وعدت المضادات Tobramycin، Amikacin، Piperacillinمن بين أفضل المضادات المؤثرة ضد P.aeruginosa إذ سجلت اقل نسبه مقاومه (%14.91) ،(%14.3) ، (%12.7) على التوالي. تم أعاده فحص 50 عزله لبكتريا P.aeruginosa لتحري عن قابليتها لإنتاج إنزيمات Extended spectrum beta-lactamases enzymes(ESBL) إذ كانت 13(%26) من العزلات منتجه لإنزيم (ESBL) و37(%74) غير منتجه لإنزيم (ESBL) وقد اجري هذا الفحص بطريقه Double disk diffusion method.


Article
Molecular Detection of CTX-M Genes in Klebsiella pneumoniae Isolated from Different Clinical Samples in Baghdad City

Author: Ahmed Salim Mohammed
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2015 Volume: 12 Issue: 1 Pages: 152-160
Publisher: Babylon University جامعة بابل

Loading...
Loading...
Abstract

CTX-M extended-spectrum β-lactamase (ESBL) producing Klebsiella pneumoniae have been reported to be an important nosocomial infections. A total of 50 K. pneumonia isolates were isolated from different clinical samples in some public hospitals in Baghdad city during the period from October to December 2013. Bacterial identification was done using conventional cultural & chemical methods &and VITEK 2 cards (GN) for identification, while the antimicrobial drug susceptibility of K. pneumoniae was performed by disk diffusion test and the minimum inhibitory concentration (MIC) testing was performed using VITEK 2 automated system (bioMérieux, France). ESBL production was phenotypically detected by double disk synergy test according to the Clinical and Laboratory Standards Institute(CLSI) guidelines. The presence of bla-gene encoded CTX-M was detected by conventional PCR technique.Out of 50 K. Pneumonia isolates,13 (26%) were ESBL producer by CDT, the minimum inhibatory concentration (MIC) of different antibiotics was performed on these 13(26%) isolates using VITEK2 AST-GN30 showed that 13 (100%) isolates were Ceftazidime,Ceftraiaxone and Cefepime resistant with MIC ≥16- ≥64 µg/ml,and 8(61.53%) of ESBL producing isolates were carbapenem sensitive 8 (61.53%) with MIC <=0.25 µg/ml. PCR assay revealed that 4 (30.76%) of the ESBL producing isolates harbored blaCTX-M gene.Extended spectrum beta lactamase mediated resistance in K. pneumonia is a cause for concern in the therapy of critically ill patients. The ESBL producing K. pneumoniae isolates were more resistant to various antimicrobial agents. This suggests that ESBL producing isolates in hospitals may cause serious infections that illustrated when these strains were responsible for a nosocomial outbreak.The findings strongly suggest that there is a need to track the detection of ESBL producers and that judicious use of carbapenems is necessary to prevent the further spread of these organisms. The prevalence of multi-drug resistant K. pneumoniae isolates especially ESBL producing bacteria was increased in Baghdad city .Phenotypic and molecular characterization of ESBL provide information about the prevalence of ESBL producing K. pneumoniae in Baghdad. The blaCTX-M was one of the predominant ESBL genes in K. pneumoniae in this study.


Article
Antimicrobial susceptibility patterns against Escherichia coli and prevalence of extended–spectrum β-lactamases

Author: Shrooq R. Kadhim
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2011 Volume: 10 Issue: 1 Pages: 47-50
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

Background There is rapid increase in bacterial resistance to antibiotics resulted in increased morbidity and mortality among patients in hospitals. Aims Monitoring of antibiotic resistance to provide data for antibiotic therapy and resistance control prescription programs. Materials and Methods Sixty seven clinical samples were collected from urine, stool, pus, wound of the patients and operating theater from some of Baghdad hospitals in 2010. Sixty two isolates of Escherichia coli were detected by bacteriological and biochemical tests, these isolates were submitted to hemolysis test and antibiotic susceptibility to 10 kinds of antibiotic disks on Mueller Hinton agar by disk diffusion method. The detection of β-lactamase production was also done and Extended-spectrum beta-lactamase (ESBL) for all the isolates. Results Hemolysis test was positive for two isolates. All the isolates of E. coli were resistant to ampicillin and cephalothin (100%) and high resistance was observed to cephalixin (95.1%), tobramycin (90.3%), doxycycline (82.2%) and nalidixic acid (70.9%). Both ciprofloxacin and nitrofurantoin was (67.7%). Low resistance was noticed to amikacin (11.2%) and trimethoprime (8.1%). β-lactamase test was positive for 57 isolates (91.9%), while three isolates (4.8%) showed positive result for extended-spectrum beta-lactamase. Conclusions Isolates of E.coli showed high resistance to ampicillin,cephalothin and cephalixin. Low resistance was revealed to amikacin and trimethoprime .Most of the isolates were positive for β-lactamase test (91.9%) and (4.8%) of the isolates were positive for extended-spectrum beta-lactamase.


Article
Molecular Detection of Some β-lactamases Genes in Uropathogenic Escherichia coli
التحري الجزيئي عن مورثات البيتالاكتاميز في الممرضة البولية ايشريكيا القولون

Authors: Ali H. Hammadi علي حسون حمادي --- Najlaa N. Yaseen نجلاء نبهان ياسين --- Harith J. F. Al-Mathkhury حارث جبار فهد المذخوري
Journal: Iraqi Journal of Science المجلة العراقية للعلوم ISSN: 00672904/23121637 Year: 2015 Volume: 56 Issue: 3A Pages: 1925-1931
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Around fifty Escherichia coli isolates were isolated from sixty midstream urine specimens collected from patients visiting hospitals in Baghdad city. Approximately, 52% of all isolates were identified as extended spectrum beta lactamases (ESBL) producer. Results demonstrated that 92% of these isolates were sensitive to carbapenems. Only four β-lactamase coding genes were detected; blaTEM, blaPER, blaVIM and blaCTX-M-2. As a conclusion, this work revealed that local E. coli isolates harboured ESBL coding genes which may contribute in its pathogenicity.

عزلت خمسون عزلة من الايشريكية القولونية من ستين عينة ادرار وسط المجرى جمعت من مرضى يزورون مستشفيات مدينة بغداد. شخص ما نسبته 52% من العزلات على انها منتجة لانزيمات بيتا- لاكتاميز موسعة الطيف. كما اظهرت النتائج ان 92% من هذه العزلات كان حساسا لمضادات الكاربابينيمات. تم التعرف على اربعة مورثات من مورثات البيتالاكتاميز و هي blaTEM و blaPER و blaVIM و blaCTX-M-2. و يمكن ان نخلص الى ان عزلات الايشريكية القولونية المحلية تحمل جينات البيتالاكتاميز موسعة الطيف.


Article
Prevalence of Metallo-β-Lactamaseproducing Pseudomonas aeruginosaisolated from different clinical samples in Baghdad province

Authors: Alaa H. Al-Charrakh علاء الجراخ --- Salwa Jaber Al-Awadi سلوى جابر العوادي --- Ahmed Salim Mohammed احمد سالم محمد
Journal: Al-Qadisiyah Medical Journal مجلة القادسية الطبية ISSN: 18170153 Year: 2014 Volume: 10 Issue: 18 Pages: 13-19
Publisher: Al-Qadisiyah University جامعة القادسية

Loading...
Loading...
Abstract

Background: Metallo beta lactamase(MBL) producing Pseudomonas aeruginosahave been reported to be an important nosocomialinfections.Pseudomonas aeruginosa is a leading cause of nosocomial infections, giving risetoa wide range of life-threatening conditions. Its intrinsic & acquired resistance to many antimicrobial agents and its ability to developmultidrug resistance imposes a serious therapeutic problem.Materials and Methods: A total of 75 P.aeruginosaisolates were isolated from different clinical samples in some public & private hospitals in Baghdad city during the period from April to August 2011.Bacterial identification was done using conventional cultural & chemical methods &and VITEk 2 cards for identification (GN), while the minimum inhibitory concentration (MIC) testing was performed using disk diffusion,E-test for Imipenem& Meropenem(oxoid, UK) & (AST-GN30)cards in VITEK 2 automated system(bioMérieux, , France).Each P.aeruginosa isolates showed resistance to Carbapenems(Imipenem& Meropenem) were subjected to Imipenem-EDTA combined disc synergy test (CDST) to investigate the production of MBL(confirmative test)Results:Out of 75 P.aeruginosa isolates,16 (21.3%) were grow on MacConkey agar supplemented with Meropenem4mg/L (MMAC),this method used as screening test, The MIC of different antibiotics was performed on these isolates using different methods(VITEK2AST-GN30,Imipenem&Meropenem E-test) showed that 6 (37.5%) isolates were Carbapenem resistant MIC ≥16µg/ml,while 4(25%) pseudomonas isolates appear to be MBL producer usingImipenem-EDTA combined disc synergy test(CDST). Discussion: MBL mediated carbapenemresistance in P. aeruginosa is a cause for concern in thetherapy of critically ill patients. The MBL producing P. aeruginosa isolates were more resistant to various antimicrobial agents. This result suggests that MBL producing isolates in hospitals may cause serious infections that illustrated when these strains were responsible for a nosocomial outbreak.The findings strongly suggest that there is a need to track the detection of MBL producers and that judicious use of carbapenems is necessary to prevent the further spread of these organisms.Conclusion: The prevalence of multi-drug resistant P.aeruginosa isolates especially Carbapenem resistant bacteria was increased in Baghdad province.Phenotypic characterization of MBLs provide information about the prevalence of MBLs producing P. aeruginosa in Baghdad.

بكتريا الزوائف الزنجارية المنتجة لانزيم Metallo-β-lactamase مثبته بانها من المسببات المهمة للاصابات والالتهابات المختلفة في المستشفيات. بكتريا الزوائف الزنجارية لها قابلية عالية على مقاومة العديد من المضادات الحياتية المستخدمة حاليا من خلال ميكانيات مختلفة منها داخلية او مكتسبة واهم الميكانيكيات هو انتاج انزيم β-lactamaseMetallo- تم جمع 75 عزلة من بكتريا الزوائف الزنجارية من مختلف العينات السريرية من بعض المستشفيات والمختبرات الحكومية والخاصة في محافظة بغداد للفترة من نيسان ولغاية اب لعام 2011. تم تشخيص البكتريا باستخدام مختلف الطرق سواء كانت فحوص كيميائية او عن طريق تشخيص البكتريا في اوساط زرعية مختلفة,كذلك تم تشخيص العزلات البكتيرية باستخدام جهاز VITEK2 وتم قياس الحساسية الدوائية للعزلات البكتيرية باستخدام disk diffusion وكذلك تم قياس اقل تركيز مثبط من العقار (MIC) باستخدام جهاز VITEK2 وكذلك طريقة E-Test لعقاريImipenem وMeropenem وتم اجراء فحص (CDST) كفحص تاكيدي للعزلات المقاومة لعقاري Imipenem ,Meropenem للتاكد من انتاج انزيم MBL .وتم التوصل للنتائج التالية:نسبة انتشار العزلات المقاومة لعقارات الكاربابينيم هي 8% وعدد العزلات البكتيرية المنتجة لانزيم MBL باستخدام الطرق المظهرية هو 4 وبنسبة 5.3%.


Article
Molecular detection of SHV-Type ESBL in E. coli and K.pneumoniae and their antimicrobial resistance profile
الاكتشاف الجزيئي لـ ESV-Type ESBL في E. coli و K.pneumoniae ومظهر مقاومتهما المضادة للميكروبات

Authors: Ahang Hasan Mawlood --- Sharmin Abdullah Omer --- Salah Tofik Jalal --- Sayran Hamad Haji
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2018 Volume: 22 Issue: 2 Pages: 262-272
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

Loading...
Loading...
Abstract

Background and objective: The increase in the incidence of Beta-lactam resistance in Gram-negative bacteria has become a main clinical problem worldwide that limits therapeutic options. The production of extended-spectrum blactamases is the major source of resistance to newer beta-lactam antibiotics in Enterobacteriaceae. This study aimed to check the presence of extended-spectrum β-lactamase producing K. pneumoniae and E. coli and the evaluation of ESBL among those isolates.Methods: A total of 120 E. coli and K. pneumoniae clinical isolates were obtained from Rizgary Teaching Hospital in Erbil City, Iraqi Kurdistan Region, during the first six months of 2016. All isolates were identified and checked for the production of ESBL using Vitek 2 automated system. The technique of PCR was performed for the detection of the presence of blaSHV gene from these isolates. The antibiotic resistant profiles for these isolates were also investigated.Results: The overall proportion of ESBL-producing E. coli and K. pneumoniae isolates, 77 (76.2%) and 15 (78.9%) isolates were ESBL producers, respectively. ESBL-producing isolates were significantly more resistant than Non-ESBL-producers (P < 0.05). PCR performed on 30 ESBL positive isolates, 21(70%) isolates were of E. coli, and 9 (30%) isolates were of K.pneumoniae. The ESBL B-lactamase related SHV gene was detected only in 11 (36.6%) isolates, 6 (28.5 %) of E. coli and 5(55.5%) of K. pneumoniae isolates respectively. All isolates were susceptible to carbapenems.Conclusion: The great diversity of ESBL and the prevalences of clinical isolates of E. coli and K. pneumoniae producing these enzymes indicate that this is an important problem in our region. The most active antimicrobial agent against isolates used in this study was carbapenem. It is, therefore strongly recommended to consider carbapenems as the drug of choice for such multi-drug resistant ESBL-producing microorganisms.

Keywords

ESBL --- blaSHV gene --- E. coli --- K. pneumoniae


Article
Detection of CTX-M-type ESBLs from Escherichia coli Clinical Isolates from a Tertiary Hospital, Malaysia
لكشف عن ESBLs من النوع CTX-M من الإشريكية القولونية السريرية المعزولة من المستشفى الثالث، ماليزيا

Authors: Fazlul MKK فضل م.ك.ك --- Farzana Y فرزانة .ي --- Najnin A نجنين أ --- Rashid MA راشد م.ا --- et al.
Journal: Baghdad Science Journal مجلة بغداد للعلوم ISSN: 20788665 24117986 Year: 2019 Volume: 16 Issue: 3 Supplement Pages: 682-688
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

The present study aims to detect CTX-M-type ESBL from Escherichia coli clinical isolates and to analyze their antibotic susceptibility patterns. One hundred of E. coli isolates were collected from different clinical samples from a tertiary hospital. ESBL positivity was determined by the disk diffusion method. PCR used for amplification of CTX-M-type ESBL produced by E. coli. Out of 100 E. coli isolates, twenty-four isolates (24%) were ESBL-producers. E. coli isolated from pus was the most frequent clinical specimen that produced ESBL (41.66%) followed by urine (34.21%), respiratory (22.23%), and blood (19.05%). After PCR amplification of these 24 isolates, 10 (41.66%) isolates were found to possess CTX-M genes. The CTX-M type ESBL producing E. coli against antibiotics belonging to different families showed the highest resistance rates to Ampicillin (100%), Cefotaxime (97%), Cefuroxime (95%), and Ciprofoxacin (86%). Carbapenem groups of antibiotics, Meropenem (89%) and Imipenem (85%) have the highest susceptibility rate among all antibiotics used in this study. The outcome of the antimicrobial susceptibility testing of significant CTX-M- type ESBL producing E. coli could be useful to avoid failure or prolong treatments.

تهدف هذه الدراسة إلى الكشف عن نوع CTX-M ESBL من الإشريكية القولونية العزلات السريرية ولتحليل أنماط حساسيتها للمضادات الحيوية. تم جمع مئة من عزلات الإشريكية القولونية من عينات سريرية مختلفة من المستشفى الثالث. تم تحديد إيجابية ESBL بواسطة طريقة نشر القرص. PCR تستخدم لتضخيم ESBL CTX- نوع من إنتاج الإشريكية القولونية من بين 100 عزلة من الإشريكية القولونية ، كانت أربع وعشرون عزلة (24 ٪) من منتجي ESBL. كانت الإشريكية القولونية المعزولة من القيح أكثر العينات السريرية التي أنتجت ESBL (41.66٪) متبوعة بالادرار بنسبة (34.21٪)، والجهاز التنفسي (22.23٪)، والدم (19.05٪). بعد تضخيم PCR لهذه الاربع والعشرون عزلة، تم العثور على أن 10 (41.66 ٪) منها تمتلك جينات CTX-M. أظهرت CTX-M من نوع ESBL الذي ينتج الإشريكية القولونية مضادة للمضادات الحيوية التي تنتمي إلى عائلات مختلفة أعلى معدلات مقاومة للأمبيسيلين (100 ٪)، السيفوتاكسيم (97 ٪) ، السيفوروكسيم (95 ٪)، والسيبروفوكساسين (86 ٪). مجموعات الكاربابينيم من المضادات الحيوية، الميروبينيم (89 ٪) وإيميبينيم (85 ٪) لديها أعلى معدل حساسية بين جميع المضادات الحيوية المستخدمة في هذه الدراسة. يمكن أن تكون نتائج اختبار الحساسية المضادة للميكروبات لـ E. ESBL من نوع CTX-M- إنتاج الإشريكية القولونية مفيدة لتفادي الفشل أو إطالة مدة العلاج.


Article
Phenotypic and Genotypic Detection of Extended-Spectrum β-Lactamases (ESBL) among Escherichia coli Isolated from Symptomatic Female's Genital Tract Infection
التحري مظهريا وجينيا عن إنزيمات البيتالاكتم واسعة الطيف ضمن الاشرشية القولونية (Escherichia coli) المعزولة من اصابات المسلك التناسلي للنساء المصحوبة بالاعراض

Author: Ahmed D. Jabbar احمد درويش جبار
Journal: Journal Of Wassit For Science & Medicine مجلة واسط للعلوم والطب ISSN: 58161992 Year: 2013 Volume: 6 Issue: 1 Pages: 59-67
Publisher: Wassit University جامعة واسط

Loading...
Loading...
Abstract

Clinical E. coli isolates (36) from women (aged 18-45 years) with symptomatic genital tract infection were detected phenotypically and genotypically for ESBL production. Phenotypically, most (30/36: 83.3%) isolates were resistant to cefotaxime (CTX) and more than half of them (26/36: 72.2%) were resistant to ceftazidime (CAZ). All (100%) and 25 (69.4%) of them were ESBLs producers by screening and confirmatory tests, respectively. Genotypically, ESBL genotypes were detected in 31/36 (86.1%) of isolates. All four ESBL genotypes were found among these isolates with predominance of CTX-M-type (26/36: 72.2%) followed by SHV-type (22/36: 61.1%), OXA-type (7/36: 19.4%), and TEM-type (1/36: 2.7%). Of These isolates, 25/36 (69.4%) had two types of ESBL genes. Seventeen (17/22: 77.2%) of SHV-type positive isolates were CTX-M positive. Six (6/7: 85.7%) of OXA-type and the TEM-type positives were also CTX-M- positive whereas the other OXA-type positive isolate was SHV-type positive. Most (22/25: 88%) isolates with two types of ESBLs were resistant to both CTX and CAZ. It can be concluded that, in female's genital tract infection, ESBL production, especially CTX-M-type, can be added as another factor, in addition to virulence factors, that select for certain strains to survive and cause disease and as vaginal E. coli is a reservoir along the fecal-vaginal-urinary/neonatal course of transmission in extraintestinal E. coli infections, our clinical microbiology labs and clinicians need to be aware of the presence of these ESBL-producing organisms and should conduct surveillance studies to ascertain this.

تضمنت هده الدراسة 36عزلة سريريه للاشريشية القولونية (Escherichia coli) جمعت من نساء (بعمر 18-45 سنة) مصابات بالتهاب المسلك التناسلي المصحوب بالأعراض. تم التحري في هذه العزلات عن إنتاج إنزيمات البيتالاكتم الواسعة الطيف (ESBL) مظهريا وجينيا. من الناحية المظهرية، اظهرت معظم العزلات (30/36: 83%) مقاومة للسيفوتاكسيم (CTX) واكثر من نصفها (26/36: 61.1%) كان مقاوما للسيفتازيديم (CAZ). اظهرت فحوصات الغربلة ان كل العزلات (100%) كانت منتجة لـ ESBL، في حين كانت النسبة (25: 69.4 %) مع الفحوص التأكيدية. تم التحري كذلك عن انزيمات البيتالاكتم واسعة الطيف جينيا، اذ كانت الانماط الجينية من الـ ESBL موجودة في 31/36 (86.1%) من العزلات قيد الدراسة. في هذه الدراسة، جميع الانماط الوراثية الاربعة من ESBL كانت موجوده، وأظهرت النتائج ان اكثرها سيادة كان CTX-M (26/36: 72.2%) يتبعها النمط SHV (22/36: 61.1%) ثم النمط OXA (7/36: 19.4%) والنمط TEM (1/36: 2.7%). من مجموع العزلات البالغة 36 هناك 25 منها (69.4%) تمتلك نمطين من جينات الـ ESBL. هنالك 17 عزلة ايجابية للنمط SHV من مجموع 22 (77.2%) تكون موجبة للـ CTX-M . وجد ايضا ان 6 عزلات (6/7: 85.7%) ايجابية للنمط الجيني OXA والنمط TEM هي ايضا موجبة للـ CTX-M في حين ان العزلات الموجبة للنمط الاخر من OXA كانت موجبة لـ SHV . معظم العزلات (22/25: 88%) التي لها نمطين من ESBL كانت مقاومة من CTX و CAZ . على ما تقدم يمكن الاستنتاج، بان انتاج ESBL في حالات التهابات المسلك التناسلي-سيما نوع CTX-M- يمكن ان يساهم (فضلا عن عوامل الضراوة الاخرى) في عملية اختيار بعض العتر للبقاء والتسبب بالامراض وبما ان بكتيريا الاشريشية القولونية موجودة في المسلك البولي التناسلي فانها تسهم في انتقال الاصابات بالبكتيريا لحديثي الولادة. مختبراتنا يجب ان تكون على دراية بوجود مثل هذه الكائنات المنتجة للانزيمات البيتالاكتم واسع الطيف واجراء دراسات لمراقبتها والتحقق منها.

Listing 1 - 8 of 8
Sort by
Narrow your search

Resource type

article (8)


Language

English (7)

Arabic (1)


Year
From To Submit

2019 (1)

2018 (1)

2015 (2)

2014 (1)

2013 (1)

More...