research centers


Search results: Found 3

Listing 1 - 3 of 3
Sort by

Article
Serum Lipoprotein (A) in Patients with Fibromyalgia Syndrome

Loading...
Loading...
Abstract

Background: Fibromyalgia syndrome (FMS) is the most common rheumatic cause of diffuse pain and multiple regional musculoskeletal pain and disability. Objective: is to assess the contribution of serum lipoprotein (A) in the pathogenesis of FMS patients.Methods: One hundred twenty two FMS patients were compared with 60 healthy control individuals who were age and sex matched. All FMS features and criteria are applied for patients and controls; patients with secondary FMS were excluded. Serum Lipoprotein (A): [Lp(A)], body mass index (BMI), & s.lipid profile were determined for both groups.Results: There was a statistical significant difference between patients &controls in serum lipoprotein (A) (P=0.013). Also there was a statistical significant correlations between serum Lp(A) & FMS patients' age( r= 0.310, P=0.034 ); but not with: duration(r= -0.222, P=0.133) , BMI(r= 0.128,P=0.390) & s.lipid profile ( p> 0.05) of FMS patients.Conclusion: s.lipoprotein (A) may play an important role in pathogenesis of FMS patients.


Article
Levels of Magnesium, Zinc, Calcium and Copper in Serum of Patients with Fibromyalgia Syndrome

Authors: Abdulnasser M. Al-Gebori --- Tarik M, Ali Rajab --- **,Mohammad H. Al-Osami --- Kisma M. Turki
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2011 Volume: 10 Issue: 2 Pages: 180-183
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND:Fibromyalgia syndrome (FMS) is a chronic musculoskeletal syndrome; almost invariably, symptoms persist at 5- and 10-year follow-ups. Several studies reported the importance of trace elements on the immune system. It plays an important role in physiological processes that are crucial for normal functioning of the immune system. Fibromyalgia could be the result of an over-active immune system, the immune system works to protect the body by attacking bacteria, viruses, and other foreign cells. When over-active, the immune system can cause severe inflammation and pain.OBJECTIVE:The main objective of this study is the association between the levels of Magnesium, Zinc, Calcium and Copper in patients with FMS.PATIENTS AND METHODS:This study was performed during the period from April 2009 to February 2010, and included 60 patients with FMS according to the ACR 1990 criteria, these criteria, a history of widespread pain has been present for at least three months affecting all four quadrants of the body, i.e., both sides, and above and below the waist, and there are 18 designated possible tender or trigger points. During diagnosis, four kilograms-force (39 newtons) of force is exerted at each of the 18 points; the patient must feel pain at 11 or more of these points for fibromyalgia to be considered. Four kilograms of force is about the amount of pressure required to blanch the thumbnail when applying pressure. Their age range was from 20-60 with the mean age of 39.95 ± 1.10 years. These patients were matched by age and sex to 30 healthy control subjects with the mean age 42.81 ± 2.16 years. Blood samples were taken from each individual and separated for the estimation of Mg, Zn, Ca and Cu levels using atomic absorption technique. The laboratory tests were done in Teaching Laboratories of the Medical City and the Department of Physiological Chemistry / College of Medicine University of Baghdad.RESULTS:The level of Mg, Zn and Ca in serum of patients with FMS was significantly lower than in serum of healthy control while the level of Cu in serum of FMS patients was significantly higher than healthy control.CONCLUSION:Thelevels of Mg, Zn, Ca concentrations in serum of patients with FMS were significantly lower than healthy control subjects, while Cu concentration in patients with FMS was significantly higher than healthy control subjects and levels of Mg, Zn, Ca and Cu may be a good indicator to evaluate this disease.

Keywords

Mg --- Zn --- Ca --- Cu and fibromyalgia syndrome


Article
Fibromyalgia Syndrome in 104 Iraqi Patients with Inflammatory Bowel Disease

Authors: Nizar Abdul lateef Jassim --- *,Faiq Isho Gorial --- Bassim.A.Asker --- Akram Ajeel Najeeb --- et al.
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2011 Volume: 10 Issue: 3 Pages: 352-357
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT: BACKGROUND: Fibromyalgia syndrome (FMS) is a common rheumatologic syndrome with multiple systemic manifestations & associated with many diseases. OBJECTIVE: To assess fibromyalgia syndrome in inflammatory bowel disease. PATIENTS AND METHODS: One hundred four Iraqi patients with inflammatory bowel disease were studied and compared with another (112) healthy individuals matched for age and sex as a control group. Full history was taken and complete clinical examination was done for all individuals in both groups. Fibromyalgia syndrome was diagnosed in all patients on base of the American College of Rheumatology (ACR) 1990 Criteria for the classification of FMS. Inflammatory bowel disease was detected by colonoscopy & tissue biopsy. RESULTS: There was a significant increase in the frequency of FMS among individuals with IBD (24 %) compared to healthy control group (5.4%) ((P-value =0.0001, Odd ratio=0.18, 95% CI=0.07-0.46). CONCLUSION: FMS occurs with increased frequency in IBD.

Listing 1 - 3 of 3
Sort by
Narrow your search

Resource type

article (3)


Language

English (3)


Year
From To Submit

2011 (3)