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Article
The value of fine needle aspiration cytology in the diagnosis of oral and jaw lesions in patients with plasma cell dyscrasias

Author: Bashar H. Abdullah بشار عبد الله
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2005 Volume: 17 Issue: 2 Pages: 41-44
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Fine needle aspiration cytology (FNAC) has been found to be very useful for the diagnosis of lesions as multiple myeloma (MM) and plasmacytomas in different parts of the body. The usefulness of such procedure has not yet been verified in the oral and maxillofacial region. This study was conducted to verify the value of FNAC in the diagnosis of oral and maxillofacial lesions in patients with plasma cell dyscrasias.Patients and methods: After clinical and radiological examination, FNAC was done by the use of 10 cc syringes with 22-23 gauge needles on 11 patients with lesions affecting the maxillofacial region. The smears stained with Leishman’s stain, to be examined microscopically.Results: Twenty eight patients were examined throughout 1.5 years period, 11 had soft tissue/or bone lesions affecting the maxillofacial region. 9 patients with MM and 2 had plasmacytoma. Of 9 patients with MM, the mandible was involved in 5 patients, 3 lesions affected the maxilla, and while in one patient the maxilla and mandible were both affected. Soft tissue lesions were seen in 6 patients. The results of FNAC showed that all lesions were due to involvement with myeloma cell infiltrates, with one exception of 2 osteolytic lesions which were due to odontogenic infection.Conclusion: FNAC is a very useful and safe procedure to diagnose different types of lesions affecting the oral cavity in patients with plasma cell dyscriasis


Article
The Predictive Value of Fine Needle Aspiration Cytology in the Assessment of Cervical Lymphadenopathy

Author: Hayder M. Abdulnabi
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2007 Volume: 6 Issue: 3 Pages: 190-193
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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ABSTRACT :BACKGROUND:Cervical lymphadenopathy is a common clinical problem that needs a prompt diagnosis to manage. FNAC plays an increasing role in the differentiation of its pathology. The aim of this study was to show the value of cytological examination in the assessment of cervical lymphadenopathy in relation to histopathological examination.METHODS :A prospective study where 50 randomly selected patients with cervical lymphadenopathy underwent fine needle aspiration cytology in the pathological department, college of medicine, Kufa university, for the period from Feb.2004 to Feb.2005.RESULTS :Non specific lymphadenitis was the common pathology in 20 patients (40%), followed by tuberculous lymphadenitis in 16 patients (32%), lymphoma in 22% and metastatic tumour in 12% of cases respectively.In 44 patients out of 50 the the pathology was confirmed histopathologically.CONCLUSION :It is proved by this study that FNAC play an important role in the diagnosis of cervical lymphadenopathy as accurate as histopathological examination.


Article
Cytological findings of testicular fine needle aspiration in a

Author: Basim Sh. Ahmed
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2012 Volume: 11 Issue: 2 Pages: 24-28
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Background: Azoospermia account for about 10–15% of male infertilitycases. It denotes the final result of different testicular alterations,ranging from non-obstructive to obstructive azoospermia which couldbe corrected surgically. The former is associated with impairment ofspermatogenic process, including hypospermatogenesis, maturationarrest and complete absence of germ cells-Sertoli cell-only syndrome(SCOS). To ascertain such azoospermia aetiology, Testicular biopsy isconsidered as the standard method. However, the popularity of Fineneedle aspiration (FNA) cytology has gained as simple and minimallyinvasive way that can help in assessing testicular function accurately.Aims: To determine causes of azoospermia, by assessing thecytological findings in testicular FNA.Patients and Methods: A prospective study for 95 azoospermicpatients was conducted from Jan 2010-Dec 2011 at private laboratoryusing FNA procedure. Here, detailed history and physical examinationwere done along with semen analysis to confirm true azoospermia.Both testes were aspirated to obviate sampling errors whenappropriate. Routine Haematoxylin and Eosin staining was alsoperformed on the smears.Results: Adequate samples were obtained from 84 (88.4%) cases,while 11 patients (11.6%) had scanty smears where cytological diagnosiscould not be obtained. These adequate smears were categorized asnormal spermatogenesis in 38 (45.2%) patients, maturation arrest atspermatocyte/spermatid level, and Sertoli cell only syndrome in 27(32.2%) and 19 (22.6%) patients, respectively.Conclusions: FNAC could permit characterization of specificcytological pictures related to testicular damage nature. It is able toidentify different azoospermic subjects and represents a reliable andprognostic parameter of seminiferous epithelium status.


Article
Breast lesion during lactation diagnosed by fine needle aspiration cytology

Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 / 24108057 Year: 2011 Volume: 53 Issue: 1 Pages: 49-53
Publisher: Baghdad University جامعة بغداد

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Abstract


Article
Cell blocks histopathology versus FNA cytology in diagnosis of primary malignant lung mass: A comparative study
الكتل الخلوية لعلم الامراض والخلايا مقابل الخلايا بواسطة شفط الإبرة الدقيقة في تشخيص كتلة الرئة الخبيثة الأولية: دراسة مقارنة

Authors: Salah A. Ali --- Jawhar T. Omer --- Tenya T. Abdulhameed
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2017 Volume: 21 Issue: 1 Pages: 1601-1607
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objective: Fine needle aspiration cytology with cell block preparation is widely used for preoperative confirmation of solitary lung mass and classification of the histologic types. This study aimed to highlight the importance of cell-block preparation in the diagnosis of primary malignant lung lesion by comparing cytomorphological preservation on paired cell block and conventional fine needle aspiration samples. Methods: During January 2012 to October 2015, a total of 100 cases with solitary lung mass were included, either visited Rizgary Teaching Hospital or Walfare private hospital. All the patients had undergone fine needle aspiration and cell block preparation under a CT-guide.Results: The samples were evaluated by the fine needle aspirations and cell blocks preparations from primary lung lesion under a CT-guide. 74% were male, and the majority of them were in the sixth and seventh decade. Squamous cell carcinoma was the most common histologic type consisting 42% of the studied cases, followed by adenocarconima (31%), small cell carcinoma (19%) and the remaining 8% were large cell carcinomas. In the assessment of agreement of cellularity between the two methods of sample preparation, cell block served better than fine needle aspiration (P = 0.715). However, this difference was statistically non-significant. A significant relation was found for morphology which was preserved in fine needle aspiration samples better than that in cell block samples (P <0.05). In contrast, all cell block samples displayed a statistically highly significant architectural preservation compared to fine needle aspiration samples (P <0.001). The sensitivity and specificity of the present study were 98.46%, 99.2% respectively. Conclusion: Direct fine needle aspiration smears and cell blocks complement each other, and our results indicate that both are needed in the diagnostic work-up of patients with a primary malignant lung mass.


Article
IS FINE NEEDEL ASPIRATION CYTOLOGY A VALID DIAGNOSTIC TOOL IN NODULAR GOITER?
هل الرشف الابري الدقيق اداة تشخيصية صحيحة لانسجة عقد الغدة الدرقية؟

Authors: MOWAFAQ M. BAHADIN موفق بهاء الدين النقشبندي --- HAYDER HUSSEIN IBRAHIM حيدر حسين ابراهيم
Journal: Duhok Medical Journal مجلة دهوك الطبية ISSN: ISSN: 20717334 (online)/ ISSN: 20717326 (Print) Year: 2016 Volume: 10 Issue: 1 Pages: 90-98
Publisher: University of Dohuk جامعة دهوك

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Abstract

Background: Fine needle aspiration cytology (FNAC) is commonly used tests for diagnosis of thyroid nodules. Is available procedure and provides specific diagnosis rapidly with minimal complications. Aim: To assess the validity of FNAC in the evaluation of thyroid nodules performed at our institution and to compare our results with other studies elsewhere.Patients and methods: This study was conducted on 51 consecutive patients who underwent FNAC for diagnosis during the period from Feb 2012 -- Feb 2015. The final histopathological diagnosis was considered the gold standard. Results: The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of FNAC for the diagnosis of neoplastic thyroid nodules were 84.6%, 97.3%, 94.1%, 91.6%, 94.8% respectively. Papillary carcinoma was the common type in neoplastic group (53.8%).Conclusion: Our study suggests that FNAC is a sensitive, specific and accurate initial diagnostic test for the preoperative evaluation of patients with thyroid nodules. Our results are comparable with current published articles and the clinician should be encouraged to use FNAC as the initial modality in assessment of thyroid nodules.

الهدف : تقييم ‌دورالتشخیص بواسطة‌ الرشف الابري الدقیق لأنسجه‌ عقد الغدة‌ الدرقية‌ ومقارنتها مع نتائج الفحص النسیجی للغده‌ بعد إجراء العملية‌ الجراحية.الطريقة‌ : هذه‌ الدراسة‌ شملت 51 حاله‌ مرضیه ( 44 من الاناث و 7 من الذكور) یعانون من عقد الغدة‌ الدرقية‌ خلال الفترة‌ من شباط 2012 لغاية‌ شباط 2015 . لكل مریض تم اخذ عینه‌ الرشف الابري علی شرائح زجاجیه‌ ومعالجتها بماده‌ الهیماتوكسلین والایوسین ودراسة‌ النتائج ومقارنتها بالزرع النسیجی لنفس المریض .النتائج : اظهرت الدراسة‌ ان الرشف الابري الدقیق ذو فاعلية كبيرة في تشخيص الاورام الخبيثة للغدة الدرقية وكانت نسبه‌ حساسية‌ الفحص 84.6% وخصوصية‌ فی التشخيص 97.3 % والدقة‌ التشخيصية‌ 94.1% الاستنتاج : اعتمادا علی نتائج هذه‌ الدراسة‌ تبین أن فحص الرشف الابري الدقیق لعقد‌ الغدة‌ الدرقية‌ هو حساس ومتخصص وذا دقه‌ تشخیصیه‌ عالیه‌ فی حالات أورام الغدة‌ الدرقية االسرطانية‌ ومقاربة لدراسات اخرى مماثلة ومن المفضل استخدامها لتقييم حالات عقد الغدة الدرقية .


Article
Per Cutaneous Ultrasonic Guided Fine NeedleAspiration in the Diagnosis and Managementof Intraabdominal Abscesses

Authors: Adel-Al-Qaysi --- Alaa G Hussein --- Yarub E Al-Khattab
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2006 Volume: 3 Issue: 1 Pages: 30-34
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Ultrasonic guided per-cutaneous
fine needle aspiration drainage technique of intraabdominal
fluid collection and/or abscess has
become the treatment of choice for the majority of
the cases, regardless of etiology.
Objective: To evaluate the role of fine needle
aspiration drainage technique with intra-cavitory
broad spectrum antibiotic instillation as a diagnostic
and therapeutic procedure for intra-abdominal
abscesses and/or fluid collection.
Methods: From September 1999 to April 2000
thirty two patients presented with intra-abdominal
abscesses and fluid collection was treated by
ultrasonic guided per-cutaneous fine needle
aspiration drainage.
Results: Complete recovery and resolution was
achieved in (93.7%) of the cases with two failure
cases which needed another surgical intervention.
Gram etiological microorganism, and (56.3%) of
cases gave a history of previous intra-abdominal
surgical intervention before symptoms started.
Conclusion: This technique was proved to be
negative bacilli were found to be the most common
cause of intra-abdominal abscesses cases as an a
desirable approach to diagnose and treat patients
with intra-abdominal abscesses and/or fluid
collection.
Key words: Fine needle aspiration, ultrasonography,
intra-abdominal abscess


Article
IMMUNOCYTOCHEMICAL STUDY OF SMOOTH MUSCLE ACTIN (SMA) IN FINE NEEDLE ASPIRATION CYTOLOGY (FNAC) OF BENIGN AND MALIGNANT BREAST TUMORS

Author: Methaq M Najem ميثاق معين نجم
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2012 Volume: 10 Issue: 1 Pages: 87-92
Publisher: Al-Nahrain University جامعة النهرين

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BackgroundMyoepithelial cells play an important role in the interpretation of breast fine needle aspiration cytology, since these cells are believed to be a component of the benign process in the breast lesion. Myoepithelial cells distinction may be difficult occasionally, so their demonstration by immunocytochemistry method through myoepithelial cell marker like smooth muscle actin is a useful diagnostic tool to differentiate between benign and invasive malignant lesions.ObjectiveTo study the role of smooth muscle actin as immunocytochemical marker in the demonstration of myoepithelial cell as an aid in the diagnosis of benign breast lesions in fine needle aspiration cytolog of breast.MethodsForty five cases of fine needle aspiration cytology of palpable female breast lesions were selected. 25 out of these 45 cases comprised 20 invasive breast carcinoma and 5 fibrocystic diseases with atypia stained with smooth muscle actin by immunocytochemistry method directly and 20 cases comprised of 10 fibroadenoma and 10 fibrocystic disease stained with smooth muscle actin after destaining from H&E stain. All of these cases had a confirmatory histological diagnosis. ResultsSmooth muscle actin staining consistently highlighted the myoepithelial cells in smears of all histologically proven benign lesions such as fibroadenomas and fibrocystic changes. In contrast, invasive breast cancers demonstrated absence of staining with smooth muscle actin that seen in benign breast lesions.ConclusionApplication of smooth muscle actin immunostaining in breast fine-needle aspirates is feasible and practical. The use of destained H&E smears provides an effective means to directly examine any atypical cluster of cells for the presence of MEC differentiation. The demonstration of presence or absence of MEC differentiation in atypical cases can provide sufficient evidence to decrease error in diagnosis (false positive) of breast fine-needle aspirates.KeywordsSmooth muscle actin, fine needle aspiration cytology, breast lesions


Article
The Role of Endoscopic Ultrasound-Guided Fine-Needle Aspiration Cytology in Diagnosis of Pancreatic Masses: Review of 40 Cases in Iraq

Authors: Rayadh A. Zaydan --- *,Khitam R. Al-Khafaji --- Sazan A. Al-Atrooshi
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2009 Volume: 8 Issue: 3 Pages: 259-265
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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ABSTRACT:BACKGROUND:Pancreatic masses are often initially identified by magnetic resonance imaging or computed tomography, during evaluation of varied symptoms. Endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA) has been proved to be safe and useful method for tissue sampling including the pancrease.OBJECTIVE:In this study we aim to find out some of the factors which may influence successful EUS-FNA of pancreatic masses, like: location of the mass, size, consistency and other significant factors.PATIENTS AND METHODS:A retrospective study of 40 patients underwent EUS-FNA of pancreatic masses, referred to Gastroenterology and Hepatology Teaching Hospital in Baghdad, from March 2005 to December 2007 (this is the first study done in Iraq); all patients were clinically suspected to have pancreatic malignancy. Cytology samples were evaluated and many other clinical variables were examined for association with EUS-FNA diagnosis.RESULT:Twenty six (65%) patients were males, and 14(35%) patients were females. Age ranged between 13-65 years with a mean of 46.6 years, the size of pancreatic masses range between 1.7-13cm, the masses were divided into 3 groups according to their sizes: <5cm 26(65%) cases, between 5-10cm 13(32.5%) cases, and >10 cm 1(2.5%) case. Consistency wise the masses were characterized as solid 34(85%) cases, mixed solid and cystic 6(14%) cases. In 13(32.5%) cases the mass was located in the body of pancrease, 25(62.5%) cases in the head, and 2(5%) cases in the tail. Regarding the cytological diagnosis: 19(47.5%) cases were benign (inflammatory conditions), and 21(52.5%) cases were malignant; including 17(80.9%) cases adenocarcinoma, 2(9.5%) cases malignant mucinous tumor, and small cell carcinoma 1(4.8%)case, and papillary and solid epithelial neoplasm (solid pseudopapillary tumor SPPT) 1(4.8%)case. Lymph node enlargement was found in 10(25%) cases.CONCLUSION:EUS-FNA can be used to sample pancreatic tumors in most patients. Communication clinical background information and imaging findings to the cytopathologist can facilitate the interpretation of the FNA specimens.


Article
Use of Fine Needle Aspiration Biopsy in Diagnosis Oral and Maxillo-Facial Tumors

Author: Emad.H.Abdulla عماد حمودي عبد الله
Journal: Tikrit Journal for Dental Sciences مجلة تكريت لعلوم طب الاسنان ISSN: 20731213 Year: 2012 Volume: 1 Issue: 2 Pages: 70-75
Publisher: Tikrit University جامعة تكريت

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Abstract

The Technique of fine needle aspiration biopsy (F.N.A.B.) was evaluated in the field of maxillofacial surgery. For this purpose comparison of cytological results with the conventional histo pathological results were take place. Seventy-two specimens were obtained by F.N.A.B. from 60 patients with age range from 3-84 years of both sexes, 11.7% of the patients had previous history of diagnosed malignant tumors. Cytological results show 40 cases(55.5%) were benign tumor, 27 cases (37.5 %) were malignant, 3 cases (4.2 %) unsatisfactory for diagnosis and 2 cases (2.8 %) were suspicious to be malignant. The statistical analysis showed that F.N.A.B. had sensitivity (92.6%), specificity (100%), positive predictive value (92.3%), and accuracy rate (96%).

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