research centers


Search results: Found 110

Listing 1 - 10 of 110 << page
of 11
>>
Sort by

Article
Estimation of the hepcidin level and some Biochemical parameters in patients of polycystic ovary Syndrome in Kirkuk city
تقدير مستوى الهيبسيدين وعدد من المتغيرات الكيموحيوية في مصل دم المريضات المصابات بمتلازمة المبيض متعدد الاكياس في مدينة كركوك

Authors: Sherin Bahgat Ayed AL- Tikriti1 شيرين بهجت عايد التكريتي1 --- Nazar Ahmed Naji2 نزار احمد ناجي2
Journal: Tikrit Journal of Pure Science مجلة تكريت للعلوم الصرفة ISSN: 18131662 Year: 2019 Volume: 24 Issue: 4 Pages: 34-39
Publisher: Tikrit University جامعة تكريت

Loading...
Loading...
Abstract

Polycystic ovary Syndrome is a common disorder in the endocrine glands, which is characterized by the aggregation of small bags surrounded by theca internal layers bloated follicles .The level of hepcidin and some other biochemical parameters were examined in (60) patients In addition to (30) blood samples of healthy control .The results showed a significant decrease in hepcidin level as well as E2 and progesterone while there was a significant increase in prolactin and testosterone in polycystic ovarian syndrome patients Compared to healthy control. There was no correlation between hepcidin and all other parameters but there was some correlations among parameters used, there was positive correlations between FSH with LH and Testosterone as well as between E2 and Testosterone and between T4 and T3 .

متلازمة المبيض متعدد الاكياس تعد من الاضطرابات الشائعة في الغدد الصم ومن اهم نتائجه عدم الانجاب، اذ يتميز المبيض بتجمع أكياس صغيرة محاطة بطبقات الجريب الداخلي المتضخمة للجريبات المتكيسة.مستوى الهيبسيدين وعدد من المتغيرات الكيموحيوية تضمنت (60 ) مريضة بالإضافة الى (30) عينة الدم للسيطرة. واظهرت نتائج الدراسة الحالية انخفاض معنوي في مستوى هرمون الهيبسيدين وكذلك في المتغيرات (Progesterone ، E2 ( بينما أظهرت متغيرات أخرى ارتفاع في مستوياتها وهي (PRL ، (Testosterone في مرضى متلازمة المبيض متعدد الاكياس مقارنة مع مجموعة السيطرة ، كما لوحظ عدم وجود علاقة ارتباطية بين هرمون الهيبسيدين مع باقي المتغيرات لكن يوجود علاقة ارتباطية ايجابية بين هرمونات FSH مع LH و Testosterone وكذلك بين FSH ، E2 و Testosterone وبين T4 و T3 .


Article
Serum resistin levels, and other hormonal and biochemical parameters in patients with polycystic ovary syndrome (PCOS)

Authors: Haider Al – Shammaa** FIBCOG --- Hedef D. El – Yassin* PhD --- Kamila H. Shamam* MSc
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2009 Volume: 51 Issue: 2 Pages: 200-203
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Polycystic ovarian syndrome (PCOS) is one of the most common cause of anovulation during reproductive life.Resistin can increase ovarian androgen production by directly stimulating ovarian theca cell or indirectly by augmenting pancreatic – B cell production of insulin.Patients and Methods: Sixty patients with PCOS who were non diabetic and not taking any medicine for the last three months were involved in the study .Thirty normal fertile female serves as control group. Fasting blood samples were aspirated from all individuals from 3rd - 6th day of the menstrual cycle to measure resistin, insulin, glucose, LH, FSH, TT3, TT4, Prolactin , Total Testosterone and lipid profile, by ELISA and routine methods.Results: mean serum resistin concentration was increased in women with PCOS compared with the control group (Mean ±SD) (19.83 ± 6.101 vs 9.36 ± 2.17) ng/ml. Serum resistin concentration correlated positively with BMI, which is divided into two subgroups. The first with BMI < 25 kg/m2 and the second with BMI &#8805;25kg/m2 in both control and patient groups. In BMI < 25kg/m2 serum resistin concentration for the control group was (8.90 ± 1.76) and (14.66 ± 2.09 ) for patients group ,while BMI &#8805; 25 kg/m2 serum resistin concentration for the control group was (10.62 ± 1.76) and (21.55 ± 5.40) ng/ml for patients group. Resistin also correlated positively with Insulin, LH, LH/FSH ratio and total Testosteron in women with PCOS but not in control. Fasting insulin level was higher in PCOS group compared with the control group (Mean ±SD) (27.45 ± 4.47 vs 13.27 ± 3.80) mIU/ml.The Fasting serum glucose was also higher in PCOS group compared with the control group (Mean ±SD) (125.27 ± 28.63 vs 92.63 ± 13.99) mg/dl. Total Testosterone level was elevated in the PCOS group compared with the control group (1.04 ± 0.37 vs 0.52 ± 0.25) ng/ml.Total Testosterone correlated positively with BMI, Resistin, Insulin, LH, and LH/FSH ratio.Conclusion: PCOS women with BMI >25 kg/m² were found to have a marked increase level of Resistin ,Insulin , Glucose ,LH ,and Total Testosterone .and a decrease level in their insulin sensitivity i.e increased insulin resistance.These data indicate that abnormal resistin secretion in obese PCOS women may play a role in causing ovarian hyperandrogenism and hyperinsulinemia. Therefore fasting serum resistin level could be helpful in diagnosing PCOS patient


Article
Primary Burkitt's lymphoma of the ovary (Case Report)

Authors: Nada Hamza Shareef --- Qasim Dawood Al-Tameemi --- Jawad Kadim Al-Dhahri
Journal: Al-Qadisiyah Medical Journal مجلة القادسية الطبية ISSN: 18170153 Year: 2011 Volume: 7 Issue: 12 Pages: 41-46
Publisher: Al-Qadisiyah University جامعة القادسية

Loading...
Loading...
Abstract

Ovarian neoplasms are rare in children . We had reported a case of primary Burkitt's lymphoma of the ovary in a 3-year-old girl presented with chronic abdominal pain with fever, pallor, and abdominal mass which was proved after laparatomy and histopathological study of the excised tumour to be a primary Burkitt's lymphoma of the ovary.

اورام المبيض نادرة في الاطفال . لقد وثقنا حالة لمرض (بيركت) اللمفاوي الابتدائي في مبيضي طفلة عمرها ثلاث سنوات كانت تشكو من الام مزمنة في البطن مع حمى وشحوب الوجه وورم في اسفل البطن . وبعد اجراء عملية فتح البطن الاستكشافي واستئصال الاورام وارسالها الى الفحص النسيجي تاكد بان المريضة مصابة ب ( ورم بيركت اللمفاوي الابتدائي في المبيضين ) .

Keywords

Burkitt --- ovary --- lymphoma


Article
HISTOLOGICAL STUDY 0F THE OVARY AND INFUNDIBULUM OF TURKEY HEN Meleagris Gallopavo
دراسة نسجية لمبيض وقمع الذيك الرومي

Author: Shakir Mahmood Mirhish Riyadh Hameed Nsaif شاكر محمود مرهش ,رياض حميد نصيف
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2013 Volume: 12 Issue: 2 Pages: 11-16
Publisher: Basrah University جامعة البصرة

Loading...
Loading...
Abstract

The present study showed that the ovary of adult turkey hens Meleagris Gallopavo is covered with simple cuboidal epithelium (germinal epithelium). Internally, two distinct regions can be distinguished. The cortex, a peripheral region contains a numerous follicles in different stages of development that are classified as primordial, primary, secondary and tertiary follicles. The primordial follicle appear distributed to the surface of sub capsular cortex surrounded by a single layer of follicular cells contains a small oocyte, showing a cytoplasm of filamentous aspect. The primary follicle appear distributed in the periphery and middle of the ovarian cortex contains and oocyte that shows an homogeneous cytoplasm with fine granules.

Keywords

Ovary --- follicles --- Hen


Article
RELATIONSHIP BETWEEN INSULIN RESISTANCE AND SERUM CONCENTRATIONS OF RESISTIN AND INSULIN-LIKE GROWTH FACTOR-I(IGF-I) ASSOCIATED WITH INDUCED POLYCYSTIC OVARY SYNDROME IN FEMALE RATS
العلا قه بين مقاومة الأنسولين وتركيز الرزستين وعامل الىمو الشبيه بالأنسولين المصاحب لمتلازمة تكيس المبايض المتعدد - المستحذث في إناث الجرذان

Loading...
Loading...
Abstract

The present study was carried out to determine the relationship between resistin , Insulin-Like Growth- I (IGF-I) and insulin resistance (IR) in female rats with induced polycystic ovary syndrome( PCOS) model and assess their association. Twenty virgin rats were divided into two equal groups: Control group: included 10 rats were given only single intramuscular injection (i.m) of 0.2 ml pure corn oil for each rat. The second PCOS group: included 10 rats given single i.m of 4 mg estradiol valerate dissolved into 0.2 ml pure corn oil for each rat. After 63 days all rats were sacrificed and blood samples were collected from inferior vena cava to obtain the serum for resistin, insulin, IGF-I, SHBG, FSH, LH and FT concentrations. The results revealed a significant increase in serum resistin, IGF-I, insulin, LH and FT concentrations in PCOS group in comparison with control group (P≤0.05),also a significant(P≤0.05) decrease in sex hormone binding globulin (SHBG) concentration in PCOS group compared with control, while, no significant difference was found in FSH concentration. The presence of insulin resistance may play an important role in the pathogenesis of increase of resistin and IGF-I in rats with induce PCOS

Keywords

Ovary --- Insulin --- PCOS


Article
Histopathological Study of Teratoma Diagnosis in Ovaries of Cattle at South of Iraq
دراسة نسيجية مرضية لتشخيص الورم النسخي في الابقار في جنوب العراق

Authors: Khalid Al-Fartosi --- Hazar Sh. Salah --- Layla M. Mehdi
Journal: Univesity of Thi-Qar Journal مجلة جامعة ذي قار العلمية ISSN: 66291818 Year: 2017 Volume: 12 Issue: 2 Pages: 113-121
Publisher: Thi-Qar University جامعة ذي قار

Loading...
Loading...
Abstract

Three cases of ovarian teratoma in bovine were diagnosed at first time in southern of Iraq. Through investigation of ovaries in 120 cows. Showed macroscopical description of ovaries lesions which were bilateral malignant tumors on external surface for each ovary (left and right).The specific characteristics of this tumor was presence of hair embedded within texture of lesion which represented to embryo remnants, As well as, the study revealed a histological exploration of tumor that. Granulosa cells under go different stages of mitotic divisions were noted during the histological study. Also tumor tissues represented as keratinized squamous epithelial tissue, contained skin adenxal structures such as hair follicle. The closed similarity between teratoma and epidermoid cysts results in misdiagnosis between them. The present study revealed that teratoma is more frequently incidence to the cattle than other demotic animal in addition this tumor had similar features to the teratoma in women.

تم تشخيص ثلاث حالات لورم في المبيض للابقار في جنوب العراق . من خلال التحري والفحص النسيجي ل 120 مبيض العائدة لاناث الابقار من مجزرة الناصرية . اظهر الفحص العياني وجود كتل ورمية فوامها شبه سائل تشغل ثلث حجم المبيض . حيث سجلت الدراسة حدوث هذه االاصابة لاول مرة في العراق والتي اعتبرت من الاصابات النادرة في الحيوانات على شكل الأورام الخبيثة .كذلك بينت ظهور الورم بشكل بشكل ثنائي على السطح الخارجي لكل المبيض (اليسار واليمين) .الخصائص المحددة لهذا الورم كان وجود الشعر جزءا لا يتجزأ من نسيج من الآفة التي تمثل بقايا الجنين، فضلا عن الدراسة كشف من خلال الفحص النسيجي لهذا الورم عدة خصائص يتميزبها. حيث لوحظت مراحل مختلفة من الانقسامات الانقسامية خخلايا جرانولوسا تحت المجهر الضوئي التي كانت تمثل الأنسجة الورمية كذلك الأنسجة الظهارية الحرشفية الكيراتينية ضهرت بشكل متزايد وانويتها تعاني من انقسامات اختزالية.علاوة على ذلك تضمنت هياكل الجلد الاثرية مثل بصيلات الشعر. ويؤدي التشابه المغلق بين الورم المسخي والخراجات البشروية إلى تشخيص خاطئ بينهما. وكشفت الدراسة الحالية أن الورم المسخي فد يصيب كثير من الأحيان الإصابة للحيوانت المستانسة ومنها الماشية بالإضافة إلى هذا الورم كانت له ميزات مماثلة إلى الورم مسخي الشائع في النساء

Keywords

Cattle --- Ovary --- Follicle --- Teratoma


Article
HISTOMORPHOLOGICAL POSTNATAL DEVELOPMENTAL STUDY OF THE OVARIES OF THE LOCAL RABBITS (Oryctologus Cuniculus)
دراسھ شكلیة نسیجیھ لتطور المبایض بعد الولاده في الارانب المحلیھ

Author: F. J. Al-Saffar, Masarat S. Almayahi فایق الصفار ،مسرات المیاحي
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2018 Volume: 17 Issue: 2 Pages: 124-146
Publisher: Basrah University جامعة البصرة

Loading...
Loading...
Abstract

This investigation was carried out to point out structural histomorphological changesthat take place in the ovaries of female local rabbits at three different postnatal periodsof their life that were kitten, immature and mature does. To conduct such project, 24rabbits were collected (8 for each age) from the local breeders. Rabbits were euthanized,dissected and subsequently ovaries were collected and fixed with 10% neutral bufferedformalin then subjected to routine processing such as dehydration, clearing, embeddingand block preparation. Finally, sections of 6 µm were prepared and stained withhematoxylin-eosin and Masson’s trichrome stains. Gross findings showed twofunctional bilateral elongated triangular-shaped ovaries situated in the abdominal cavitysuspended by mesovarian ligament with absence of true ovarian bursa. Microscopicfindings revealed prominent structural changes in the ovaries of immature doescompared to those of kittens and mature does indicated that immature does after theperiod of weaning face great developmental growth and changes

أجریت ھذه الدراسة للاستدلال على التغیرات الشكلیائیھ-النسجیھ التي تحدث في مبایضاإناث الأرانب المحلیة فيثلاث فترات عمریھ محتلفھ ما بعد الولادة في حیاتھم والتي كانت الھریرة الصغیره والغیر ناضجة والناضجة.تم جمع ٢٤من الأرانب ) ٨لكل عمر( من المربین المحلیین لإجراء ھذه الدراسھ.تم قتل الأرانب بشكل رحیم ، ومن ثم تشریحھا ،بعدھا تم جمع المبایض وثبتت باستخدام ٪١٠من الفورمالینالمتعادل ، وثم اخضاع النماذج للتقنیات النسیجیھ الروتینیة مثل التجفیف ، الترویق ، التطمیر بالشمع وإعدادالبلوكات منھا. ً وأخیرا ، تم إعداد المقاطع المكونة من ٦میكرون واصطبغت بصبغات ھیماتوكسیلین-إیوسینوالماسون ثلاثة الكروم.أظھرت النتائج العیانیھ وجود مبیضین مثلثتي الشكل ومتواجدین في التجویف البطني یعلقھما الرباط المبیضيوبدون وجود الجراب المبیضي الحقیقي.بینت النتائج المجھریھ أن التغییرات التركیبیھ البارزة تكون في مبایض الغیر الناضجة بالمقارنة مع تلك التيفیالھریرات الصغیره والقطط الناضجة وتحدث النتائج البارزه في الغیر ناضجھ بعد فترة الفطام التي تواجھ تغیراتنمو كبیرة.وأظھرت البیانات وجود جریبات ما قبل التبویض وفي حالة النضج ولا توجد علامات على وجود الإباضة لأن ھذهالحیوانات التي خضعت للدراسة تبیض بحافز التزاوج وكانت كلھا عذراء ولم یسمح لھا للتزاوج مع الذكور


Article
The use of oral thiazoldinediones in correction of hormonalabnormalities among unmarried women with resistant PCO .

Authors: Waffaa N Saieed --- Inas Taha --- Wisam Akram
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2006 Volume: 48 Issue: 4 Pages: 378-382
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background; Polycystic disease of the• ovary is complex of symptoms with virious clinical, hormonal and biochemical abnormalities.
Setting; AL-Elwyia Maternity Teaching Hospital
Aim; to test the ability of pioglitazone in correcting biochemical and hormonal changes among unmarried women with PCO.
Design; Prospective
Methods: 23 women with PCO in whom previous treatment with metformin has failed were recruited to participate in the study. All the women were single with chronic unovulation and menstrual abnormalities and hirsutism. They were put on pioglitazone 30 mg daily for 6 months. FSH, LH, LH/ FSH, fasting insulin level, free testosterone, estradiol, and serum sex binding globulin as well as mid luteal progesterone were assessed prior to treatment and six months later. Results; there was significant reduction in the mean serum fasting insulin level [53.08+12.75 vs. 22.43+4.29: P< 0.001]. In addition there was significant reduction in the mean serum free testosterone, LH and LH/ FSH ratio [3.21+0.36 vs. 1.68+0.43: P<0.001], [15.19+4.43 vs. 10.72+3.08: P<0.001], [2.41+0.23 vs. 1.71+0.12: P<0.001] respectively. In addition mean serum progesterone at mid luteal phase increased significantly [2.44+1.11 vs. 18.61+2.28: P<0.001]. No woman during the treatment course has shown any sign of liver impairment or toxicity.
Conclusion; Pioglitazone is an insulin sensitizing drug which may be useful among women with PCO in whom previous treatment with metformin has failed. Yet, caution should be practiced in prescribing the drug until further studies confirm its safety and efficacy.


Article
PATHOLOGICAL CHANGES IN GENITAL ORGANS OF FEMALE ALBINO MICE AFTER TREATMENT WITH PENTOXIFYLLINE

Loading...
Loading...
Abstract

BackgroundLittle to our knowledge has been attempting to show the effect of pentoxifylline (PTX) on ovulation or oogenesis. In a few studies of man with asthenospermia oral treatment with PTX produced significant increase in sperm concentration and motility.ObjectiveStudy the effect of PTX on ovulation and oogenesis in albino mice.MethodsSixty albino mice randomly divided into 6 equal groups: Group 1 received tap water and considered as a control group. Group 2 treated with 16 mg of PTX/Kg/BW/daily for 2 weeks. Group 3, 4, 5, and 6 treated with same dose for 4, 6, 8, 10 weeks respectively. Post-mortem examination done according to the time of treatment and the reproductive systems were excised and processed for light microscopic examination.ResultPTX administration causes an increase in the diameter of the ovary and in the total number of ovarian follicles and their diameters especially Graafian and secondary follicles. In addition, highly significant increase in the numbers of corpus lutea especially in those groups treated for longer time was noticed. Moreover, an increase in the thickness of uterine and oviduct epithelial lining due to hyperplasia and an increase in the diameter of endometrial glands and oviducts was demonstrated.ConclusionsWe concluded that administration of PTX has a significant effect on the female genital organs especially if given in small doses for 10 weeks. This will definitely influence reproduction and litter size manifested after mating with untreated males.Key wordsPentoxifylline, ovary, uterus, fallopian tube

Keywords

Pentoxifylline --- ovary --- uterus --- fallopian tube


Article
Role of Metformin on Recurrent Miscarriage and Other Pregnancy Complications in Women with Polycystic Ovarian Syndrome

Author: Inaam Faisal Mohammed
Journal: Iraqi Journal of Embryos and Infertility Researches المجلة العراقية لبحوث الأجنة والعقم ISSN: eISSN: 26166984 / pISSN: 22180265 Year: 2017 Volume: 7 Issue: 1 Pages: 1-6
Publisher: Al-Nahrain University جامعة النهرين

Loading...
Loading...
Abstract

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Polycystic ovary syndrome signs and symptoms often begin soon after menarche. In some cases, PCOS develops later during the reproductive years, for instance, in response to substantial weight gain. The PCOS produces symptoms in about 5-10% of women of reproductive age(12-45 years) and it is one of the leading causes of female subfertility.Women with PCOS suffer not only from subfertility, but also from a high rate of early pregnancy loss. About 30-50% of clinically confirmed early pregnancy loss are associated with PCOS.In addition to early pregnancy loss, women with PCOS have increased risk of recurrent miscarriage ,which defined as 3 or more consecutive pregnancy loss before 20 week. Metformin hydrochloride, an insulin sensitizing agent, has been shown to have encouraging effects on several aspect of PCOS like insulin sensitivity, plasma glucose concentration & lipid profile.It is found that using Metformin during pregnancy in women with PCOS may reduce the pregnancy loss and also reduce the risk of gestational diabetes,intrauterine growth retardation(IUGR) & preterm labor.

Listing 1 - 10 of 110 << page
of 11
>>
Sort by
Narrow your search

Resource type

article (110)


Language

English (95)

Arabic (7)

Arabic and English (7)


Year
From To Submit

2019 (9)

2018 (23)

2017 (14)

2016 (8)

2015 (13)

More...