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LEPTIN EFFECTS ON , THYROID HORMONES AND SOME BIOCHEMICAL PARAMETERS OF FEMALE RABBITS (LEPUS CUNICULUS) SERUM.
تاثير اعطاء هرمون اللبيتين على مستوى هرمونات الغدة الدرقية وبعض المعايير الكيميوحيوية لمصل دم اناث الارانب

Author: Rashad F.Ghadhban Ala AL-Deen H. Jawad رشاد فاضل غضبان علاء الدين حسن جواد
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2013 Volume: 12 Issue: 1 Pages: 178-189
Publisher: Basrah University جامعة البصرة

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Abstract

Thirty local female rabbits were divided randomly and equally into three groups. The 1stgroup used as control which injected with phosphate buffer salin. The 2nd group was injecteddaily with leptin (5μg/animal) S/c. The 3rd group was injected subcutaneously daily with(10μg/animal) S/c. All groups were treated for 60 days, and blood samples were collected every15 days, serum was tested for T3, T4 hormones, total Cholesterol (TC), HDL (height densitylipo-protein) , LDL (low density lipo- protein), TG (triglycerides) and Body weight was takenevery 15 days during the experiment .The result show significant (P≤0.05) decreased in body weight after administration ofleptin in two doses. Significant increased in Thyroid hormone after leptin administration. Whilelipid profile (TC, TG, LDL, HDL,VLDL) show significant decreased with leptin treatment(5 and10μg/animal) S/c.

Keywords

rabbits --- T4 hormones --- Cholesterol


Article
Clinical Study for Thyroid Status in Type 2 Diabetes Mellitus Patioents
دراسة سريرية عن حالة الغدة الدرقية في مرضى السكري من النوع 2 Patioents

Authors: Ali Abd AL-Rassol Hussein علي عبدالرسول حسين --- Fatin Fadhel AL-kazzaz فاتن فاضل الكزاز
Journal: Diyala Journal For Pure Science مجلة ديالى للعلوم الصرفة ISSN: 83732222 25189255 Year: 2012 Volume: 8 Issue: 1 Pages: 88-96
Publisher: Diyala University جامعة ديالى

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Abstract

The fact that insulin and thyroid hormones influenes each other actions assumes significance since diabetes mellitus and thyroid disease are two commen endocrine disorders in adult population in Iraq. Hyperglycems is considered amajor initor to other tissue damaje throughout diabetes mellitus development ,for all above the present study amied to investigate the glycemia affect type 2 on thyroid gland measuring T3,T4,TSH and F.B.glucose in sera of 26 patients with DM2who diagnosed by supervison in teaching AL-kiadhmia Hospital during the period February 2010 and Aprial 2010 .The invesitigation have been compared with 33 healthy individuals as control group This study revealed that DM2 is prevalent among female at age (40-49)years with non significant differences (p>0.05) Laboratory inuestigations showed that hormons leavels of T3&T4 had been increased significantly (p<0.05) among diabetic patiants type2 while pituitary hormone TSH had decreased non-significantiy in compared to control group(p>0.05). Finally the study revealed appositive correlation between F.B.glucoses and TSHand negative association for F.B.glucoses with T3&T4 In conclusion it can said patients with DM2would be with hyperthyroidism throught time

ان حقيقة تاثير عمل هورمونات الغدة الدرقيه والانسولين احدهم على الاخر يبدو معروفآ اذ ان داء السكري وامراض الدرقيه من الامراض الغديه الشائعة بين الناس البالغين في العراق . ويعتبر ارتفاع مستوى الكلوكوز في الدم البادىء الرئيسي للتلف لبقيه انسجة الجسم خلال تطور مرض السكري هدفت T3,T4, على الغدة الدرقيه من خلال قياس DM2 الدراسه الحاليه الى تقيم ثاثير داء السكري نوع الثاني الذين تم تشخيصهم من قبل اطباءDM2ومستوى الكلوكوز الصائمي في امصال 26من المرضى بTSH اخصائين في مستشفى الكاظميه التعليمي خلال فترة شباط 2010 الى نيسان 2010 . ثم مقارنة النتائج مع 32 من الاشخاص الاصحاء كمجموعة سيطرة . اكثر انتشارآ مابين النساء وباعمار 40-49 سنه بصورة غير ملحوظه DM2بينت نتائج الدراسه ان مابين المرضى 0.05>P بصورة ملحوظه T3,T4. واشارت النتائج المختبريه ارتفاع مستويات 0.05

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