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Epidemiological Study of Toxoplasmosis And Cytomegalovirus in Pregnant Women in Kerbala
دراسة وبائيه لداء القطط والفيروس المضخم للخلايا في النساء الحوامل في محافظه كربلاء

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Abstract

Objectives: Identifying the seroprevalence of acute anti-Toxoplasma gondii and anti-CMV IgM and chronic IgG antibodies, the environmental and behavioral factors andsome socio demographic data and influencing CMV as co-factor to infected withToxoplasma gondii of the study sample.Methods: A descriptive cross sectional study done on 240 pregnant women(13-43years old). All the studied women were interviewed and blood samples were taken andused Minividas technique for detect ion ant ibodies ( IgM and IgG) .Results: The seroprevalence of anti-Toxoplasma gondii antibody was (28.3%) forchronic Toxoplasmosis (IgG),and (0.8%) for acute Toxoplasmosis (IgM).While resultsfor Cytomegalovirus (CMV)infection revealed that (92.08% ) positive for chronicCMV (IgG) and (0.8%) positive for acute CMV(IgM) ,The peak age for acquisition ofthe infection was (20-29 year old ) , There was a statistical significant associationbetween seroprevalence with cat exposure ,revealed this results significant associationbetween Toxoplasmosis and CMV infection and influencing CMV as co-factor toinfected with Toxoplasma gondii and proved this results significant associationbetween seroprevalence Toxoplasmosis and CMV infection with birth defect.

هدف البحث : تحدید انتشار الإصاة بداء المقوسات سهل الاصا عامل مساعد * ذلك علاقة الفیروس * طة بها و ة المرت * ة والسلو ة، البیئ الاجتماعحث . عینة ال / ة لد القند- عینة من ( 240 ) أم ا رءه حامل تت ا روح أعمارهن بین ( ١٦ / ة لد ة مقطع طريقة العمل :نوع الد ا رسة هو وصفحث. ة واخذ عینة من الدم من عینة ال المقابلة الشخص ان * ٤٣ سنة .)جمع المعلوماتالنتائج : أظهرت النتائج أن الانتشار المصلي للأجسام المضادة من النوع "ج"في مصول العينات المسحوبة من( 61 سيده من إجمالي 240 ) % النساء الحوامل ,والتي تدل على الاصابه المزمنة للمقوسات القندية كانت 28.


Article
Epidemiological Study of Toxoplasmosis And Cytomegalovirus in Pregnant Women in Kerbala
دراسة وبائيه لداء القطط والفيروس المضخم للخلايا في النساء الحوامل في محافظه كربلاء

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Abstract

Objectives: Identifying the seroprevalence of acute anti-Toxoplasma gondii and anti-CMV IgM and chronic IgG antibodies, the environmental and behavioral factors andsome socio demographic data and influencing CMV as co-factor to infected withToxoplasma gondii of the study sample.Methods: A descriptive cross sectional study done on 240 pregnant women(13-43years old). All the studied women were interviewed and blood samples were taken andused Minividas technique for detect ion ant ibodies ( IgM and IgG) .Results: The seroprevalence of anti-Toxoplasma gondii antibody was (28.3%) forchronic Toxoplasmosis (IgG),and (0.8%) for acute Toxoplasmosis (IgM).While resultsfor Cytomegalovirus (CMV)infection revealed that (92.08% ) positive for chronicCMV (IgG) and (0.8%) positive for acute CMV(IgM) ,The peak age for acquisition ofthe infection was (20-29 year old ) , There was a statistical significant associationbetween seroprevalence with cat exposure ,revealed this results significant associationbetween Toxoplasmosis and CMV infection and influencing CMV as co-factor toinfected with Toxoplasma gondii and proved this results significant associationbetween seroprevalence Toxoplasmosis and CMV infection with birth defect.

هدف البحث : تحدید انتشار الإصاة بداء المقوسات سهل الاصا عامل مساعد * ذلك علاقة الفیروس * طة بها و ة المرت * ة والسلو ة، البیئ الاجتماعحث . عینة ال / ة لد القند- عینة من ( 240 ) أم ا رءه حامل تت ا روح أعمارهن بین ( ١٦ / ة لد ة مقطع طريقة العمل :نوع الد ا رسة هو وصفحث. ة واخذ عینة من الدم من عینة ال المقابلة الشخص ان * ٤٣ سنة .)جمع المعلوماتالنتائج : أظهرت النتائج أن الانتشار المصلي للأجسام المضادة من النوع "ج"في مصول العينات المسحوبة من( 61 سيده من إجمالي 240 ) % النساء الحوامل ,والتي تدل على الاصابه المزمنة للمقوسات القندية كانت 28.3221 سيده من إجمالي 240 ) بينما الانتشار المصلي للأجسام المضادة ) % وللفيروس المضخم للخلايا هي 92.2


Article
Risk of birth defects and other childhood adverse outcome associated with in vitro fertilization

Authors: Adnan M. Hamawandi --- Khalid H. Salih --- Hind N. Ayoub --- Amanj R. Zangana
Journal: Iraqi Journal of Embryos and Infertility Researches المجلة العراقية لبحوث الأجنة والعقم ISSN: eISSN: 26166984 / pISSN: 22180265 Year: 2014 Volume: 4 Issue: 2 Pages: 40-46
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background:In vitro Fertilization (IVF) is an important alternative for infertile couples, there is anincrease in the number of children conceived by IVF worldwide.Objective:The aim of this study was to assess the risk of birth defects and adverse outcome amonginfants and children conceived by in vitro fertilization in Sulaimani-Iraq.Patients and Methods:This case-control study was carried out on 160 children, 75 were product ofIVF(using ICSI) and 85 were product of natural conception. Data collectedregarding mother age, father age, duration of infertility before pregnancy with theindex child, any complication during pregnancy, age of the child, gender, mode ofdelivery, gestational age, weight at delivery, history of neonatal admission andit’s cause, admission to hospital after neonatal period, and history of surgicaloperation. All children were examined for any gross anomaly, cardiovascular,respiratory, gastrointestinal, skeletal, urological and neurologic abnormality.Results: IVF was a risk factor for prematurity (OR, 7.844 95% CI 3.025 - 20.339) ,LBW (OR, 4.645 95% CI 2.038 -10.587), Congenital anomaly (OR, 1.362 95% CI 0.720 -2.576), predominance of male gender (OR, 1.340 95% CI 0.719-2.498), neurodevelopmentaldelay(OR,1.333 95% CI 0.672- 2.646), admission to NICU (OR,1.703 95%CI 1.052-2.758 ), C/S delivery (OR, 1.972 95% CI 1.507-2.581), and childhoodhospitalization (OR, 1.193 95% CI 0.838-1.696), also there was statistically significantassociation with multiple pregnancy.Conclusions:IVF carries increased risk of LBW, prematurity, congenital anomaly, neuro-developmentaldelay, admission to NICU, childhood hospitalization, C/S as a mode of delivery andpredominance of male gender.

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