Olive oil extract was studied for diabetes mellitus that induced by alloxan in mice to development herbal medicine against the non communicable disease. We have measured the fasting blood glucose level (serum). Hyperglycemia and hyperlipidemia are two important characters of diabetes mellitus. Hyperlipidemia developed in these experimental diabetic mice was assessed by quantification of total cholesterol (TC), high-density lipoprotein cholesterol (HDLc), and triglyceride (TG) in serum, so the extract of olive oil have some remedial effects against alloxan-induced diabetic mice. Forty five adult male mice used in this study, animals were divided into three equal groups :Control without any treatment (A), alloxan treated (B) and group(C) induced diabetic and treated with the extract of olive oil (0.5ml/100g B.W). All animals were sacrificed 2,4,6 weeks post treatment respectively. After treatment of extract of olive oil in alloxan-induced diabetic mice the result showed a significant remedial effect on blood glucose level, None of the extract has any metabolic toxicity induction in general (by measuring level of GPT, GOT and ALP).

دراسة تأثير مُستخلص زيت الزيتون على داء السكري المحدثة في الفئران المختبرية بفعل الألوكسان من أجل تطوير دواء عشبي ضد الأمراض غير المعدية، إذ تم قياس مستوى السكر في دم الفئران ويعد إرتفاع مستوى السكر في الدم و مستوى الدهون من أهم الأعراض لداء السكري و تم فحص مستوى الدهون في الفئران المختبرية المصابة بمرض السكري بوساطة تقدير الكولسترول الكلي TC وكذلك البروتينات الدهنية العالية الكثافة للكولسترول (HDLc) والكلسيريدات الثلاثية TG في مصل دم الفئران المختبرية. تمت دراسة هذا البحث على فئران ذكرية عددها (45) فأرا وتم تقسيم هذه الفئران على ثلاث مجاميع متساوية إذ أستعملت مجموعة (A) بوصفها مجموعة سيطرة بدون أي علاج ومجموعة (B) وتمت معاملتها بالألوكسان ومجموعة (C) المصابة بمرض السكري والمعالجة بوساطة مُستخلص زيت الزيتون( 0.5مليلتر/100غم) من وزن جسم الحيوان، وبعدها تم التضحية بها بعد 6,4,2 أسابيع من التجريع. وتمت ملاحظة تأثيرات علاجية مهمة لمُستخلص زيت الزيتون في مستوى الكلوكوز في مصل دم الفئران المختبرية المُصابة بمرض السكري بوساطة الألوكسان. وقد تضاءل مستوى الدهون في المصل بشكل ملحوظ بعد التجريعات المنتظمة لمُستخلص زيت الزيتون في الفئران المختبرية المُستحث فيها داء السكري بمركب الألوكسان، ولم يلاحظ أي تغييرات إنزيمية في مصل دم الفئران بفعل مُستخلص زيت الزيتون بشكل عام بوساطة قياس مستوى مصل(GPT و GOTوALP)، كذلك تم ملاحظة التأثيرات العلاجية لمُستخلص زيت الزيتون ضد مرض السكري المتسبب بفعل الالوكسان.

Olive oil --- alloxan --- hypolipidemic

In this study, the number of times of heating of olive oil was studied. For the different refineries, the study was conducted using a temperature of 300K and for several times to determine the validity of the olive oil which is used for frying purposes after it was used for more than once times. It was found that there were significant changes in the behavior of the photophysical behavior like absorption and emission; there are changes in the nature and composition of the olive oil molecule, which makes it not useful for human use. The number of heating times was ten. The heating times also showed significant changes in the nature of the oil, such as color, taste, density, and smell.

olive oil --- frying --- cooking --- spectroscopic

Background: During acrylic resin processing, the mold must be separated from the surface of the gypsum to preventliquid resin from penetrating into the gypsum, and water from the gypsum seeping into the acrylic resin. For manyyears, tin foil was the most acceptable separating medium, and because it's difficult to apply, a tin-foil substitute isused. In this study, olive oil is used as an alternative to tin foil separating medium for first time, and evaluating its effectas a separating medium on some mechanical properties such as (indentation hardness and transverse strength) ofacrylic resins denture base comparing it with those processed using tin-foil and tin foil substitute such as (cold moldseal) separating medium.Materials and Methods: One hundred Twenty four acrylic resins samples (124) were prepared falling in two maingroups: (heat and cold-cured acrylic denture base resins), for each group three types of separating medium wereused and five tests (10 samples) for each test were carried out, and (4) samples for the chemical composition.Results: Tin foil is one of the most satisfactory separating media in getting the best properties when using it as aseparating medium, while, a statistically no-significant difference have been noticed between olive oil and coldmoldseal samples concerning mechanical properties of tested groups. Infrared spectroscopy analysis showed that,no changes were found in the chemical composition of both heat and cold-cured acrylic resins denture base afterusing olive oil as a separating medium.Conclusion:The present study concluded that olive oil may be used as a substitute for tin foil and cold – mold sealseparating medium in processing both heat and cold – cure acrylic resin denture base.

Acrylic resin separatingmedium olive oil --- mechanical properties

Back ground: During acrylic resin processing, the mold must be separated from the surface of the gypsum to preventliquid resin from penetrating into the gypsum, and water from the gypsum seeping into the acrylic resin. For manyyears, tin foil was the most acceptable separating medium, and because it's difficult to apply, a tin-foil substitute isused. In this study, olive oil is used as an alternative to tin foil separating medium for first time, so the aim of the studywas to evaluate its effect as a separating medium on some physical properties such as (surface roughness, watersorption and solubility) of acrylic resins denture base comparing it with those processed using tin-foil and tin foilsubstitute such as (cold mold seal) separating medium.Materials and methods: One hundred forty two acrylic resins samples (124) were prepared falling in two main groups:[heat and cold-cured acrylic denture base resins ], for each group three types of separating medium were used andfive tests (10 samples) for each test were carried out , and (4) samples for the chemical composition.Result: From the result obtained, tin foil is one of the most satisfactory separating media in getting the best propertieswhen using it as a separating medium, while, a statistically no-significant difference have been noticed betweenolive oil and cold-mold seal samples concerning physical and mechanical properties of tested groups. Infraredspectroscopy analysis showed that, no changes were found in the chemical composition of both heat and coldcuredacrylic resins denture base after using olive oil as a separating medium.Conclusion: Lastly, from the results of this study it may be concluded, that olive oil may be used as a substitute for tinfoil and cold – mold seal separating medium in processing both heat and cold – cure acrylic resin denture base

Acrylic resin --- separating medium --- olive oil physical properties

This research was carried out in order to investigate whether the puri ed bitter orange (Citrus aurantium) volatile oil puri- ed from peels has a potentiality to induced DNA damage if administrated orally in vivo. White adult male rats (180- 250g) were divided into ve groups each group with ve individuals. The rst three groups administrated three different con- centration of the puri ed citrus essential oil 100, 200 and 300μl/ kg Body weight (Bwt). The fourth group administrated olive oil and served as positive control group. The fth was administrated water as negative control group. Dosing for all groups were two times weekly for one month period. To detected DNA damage, alkaline single cell gel electrophoresis (SCGE) for the blood samples was carried out for all groups. Parameters of nuclear olive moment, comet tail length, and DNA on comet tail were calculated. Results showed that there were no signi cant differences between treated and control untreated groups as well as olive oil administrated group. These results indicate that citrus volatile oil has no genotoxic effect and it was safe and tolerable in the highest dose used for the speci ed period of time conducted.

جرى في هذا البحث التحري فيما لو كان للزيت العطري المنقى النارنج )Citrus aurantium( قدرة على إحداث ضرر في المادة الوراثية DNA عند تجريعه من خ ل الفم داخل الجسم الحي . إستخدمت في التجارب الجرذان البيضاء بوزن تراوح بين 180 إلى 250 غرام والتي قسمت إلى خمس مجاميع كل مجموعة تحتوي على خمسة أفراد وجرى تجريع المجاميع الث ثة ا ولى تركيز مقدارها 100 و200 و300 مليغرام من الزيت العطري المنقى من قشور النارنج لكل كيلوغرام من وزن الجسم في حين جرعت المجموعة الرابعة زيت الزيتون التجاري المتوفر في ا سواق المحلية وأعتبرت مجموعة مقارنة موجبة وجرعت المجموعة الخامسة الماء النقي وعدت مجموعة مقارنة سالبة. جرعت كل المجاميع بجرعتين إسبوعا ولمدة أربعة أسابيع )شهر كامل( وبعد إنتهاء فترة التجريع جرى التحري عن مدى تضرر المادة الوراثية في الحيوانات المجرعة بإستخدم فحص هجرة الخ يا المنفردة في المجال الكهربائي القاعدي والمعروف بفحص المذنب أو الكومت comet assay لعينات دم الحيوانات تحت التجربة وقد أستخدم قياسات كل من مسافة حركة جسم النواة للخ يا و طول الذنب النووي في الخ يا وكمية المادة الوراثية DNA في الذنب الناتج لتحديد ذلك التضرر. أظهرت النتائج عدم وجود فروقات معنوية من حيث تضرر DNA بين الجاميع المجرعة بزيوت النارج العطرية ومجاميع المقارنة الموجبة والسالبة تحت الدراسة وبمختلف التراكيز مما يدل على عدم وجود سمية وراثية للزيوت العطرية المنقاة منالنارنج وهناك قدرة تحمل للجرعة ا على المستخدمة وخ ل الوقت المستخدم للتجريع .

citrus oil --- rat --- comet assay --- olive oil --- tail moment --- citrus oil --- rat --- comet assay --- olive oil --- tail moment